Purpose: To evaluate the efficacy of the dexamethasone implant on the electrophysiological profile of Diabetic Macular Oedema (DMO) patients over six months. Methods: In this prospective, single-center study 30 eyes of 22 patients were examined using comprehensive baseline assessments including best-corrected visual acuity (BCVA), central retinal thickness (CRT), contrast sensitivity (CS) and multifocal electroretinogram (mfERG), before and after 0.7mg dexamethasone implant injection, with follow-ups at months 1, 2, 4, and 6. The study employed mixed models to analyse within-subject and between-subject correlations, considering the complexities of multiple measurements per subject. Results: At baseline, BCVA was 0.66 ± 0.104 logMAR, improving to 0.568 ± 0.104 logMAR by month 6 (P > 0.05). CRT significantly reduced from 521 ± 28.7 μm to 336 ± 28.7 μm (P < 0.05). CS slightly increased from 26.8 ± 1.23 letters to 28.5 ± 1.05 letters (P > 0.05). P wave amplitude saw a notable rise from 33.4 ± 5.66 μV to 47.9 ± 5.43 μV (P < 0.05). P wave implicit time changed minimally from 47.4 ± 0.503 seconds to 48.0 ± 0.503 seconds (P > 0.05). No severe adverse events were recorded. Conclusion: These results underscore the 0.7mg dexamethasone implant’s potential in improving certain electrophysiological markers in DMO, while also highlighting the need for further investigation into its comprehensive impact on retinal function.

Purpose: To examine the seasonality of retinal detachment (RD) and explore global patterns and contributing factors through a narrative review. Methods: Studies investigating seasonal trends in RD incidence across diverse regions were analysed for peak seasons, meteorological influences, and behavioural factors. Results: RD seasonality varies by region. Northern climates (e.g., Finland) report summer peaks linked to prolonged daylight, while warmer climates (e.g., Kuwait) show winter peaks associated with outdoor activity. Some studies found correlations with temperature, light, and atmospheric pressure, while others reported no seasonal variation. Conclusions: RD seasonality reflects a complex interplay of environmental and behavioural factors. Future research should focus on standardised methodologies to clarify these relationships and inform preventative strategies.