Ignacio Ramirez Gallegos

Mr. Ignacio Ramirez Gallegos

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Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 March 2025 in Nutrients
Verified
Journal Article
Open access
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IGIgnacio Ramirez Gallegos
Ignacio Ramirez Gallegos
PTPedro Juan Tárraga-López
Pedro Juan Tárraga-López
HPHernan Paublini
Hernan Paublini
ÁGÁngel Arturo López González
Ángel Arturo López González
CSCristina Martorell Sanchez
Cristina Martorell Sanchez
JRJosé Ignacio Ramírez-Manent
José Ignacio Ramírez-Manent
Introduction: Metabolic age (MA) is the difference between an individual’s actual age and the age of their body based on physiological and biological factors. It is an indicator that reflects a person’s physical and biological state, regardless of chronological age. Insulin resistance (IR) is a health disorder in which tissues exhibit a reduced response to the circulating glucose uptake stimulated by insulin. Objective: The aim of this study is to evaluate the association between MA, determined through bioelectrical impedance analysis, and the risk of IR, assessed using validated scales, in a cohort of Spanish workers. Methodology: A descriptive cross-sectional study was conducted on 8590 Spanish workers to assess the association between MA and a set of sociodemographic variables, health habits, and IR risk scales such as the Triglyceride–Glucose Index (TyG Index), Metabolic Score for Insulin Resistance (METS-IR), and Single Point Insulin Sensitivity Estimator (SPISE). Results: All analyzed variables were associated with MA values, with the strongest associations observed for IR risk scale values (OR 4.88 [95% CI 4.12–5.65] for METS-IR, 4.42 [95% CI 3.70–5.15] for SPISE, and 3.42 [95% CI 2.97–3.87] for the TyG Index) and physical activity. Conclusions: Metabolic age is influenced by sociodemographic variables such as age, sex, and social class; health habits such as smoking, physical activity, and adherence to the Mediterranean diet; and by IR risk scale values.

7 April 2024 in Nutrients
Verified
Journal Article
Open access
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IGIgnacio Ramirez Gallegos
Ignacio Ramirez Gallegos
MAMarta Marina Arroyo
Marta Marina Arroyo
ÁGÁngel Arturo López González
Ángel Arturo López González
MHmaria teofila vicente herrero
maria teofila vicente herrero
DVDaniela Vallejos
Daniela Vallejos
JRJosé Ignacio Ramírez-Manent
José Ignacio Ramírez-Manent
Background: Cardiovascular and metabolic diseases include a large group of pathologies and constitute one of the most serious chronic health problems facing the 21st century, with high rates of morbidity and mortality worldwide. Unhealthy diets influence the development of these pathologies. The Mediterranean diet can be an important part in the treatment of these diseases. The objective of this study was to assess the effect of a program that aims to increase adherence to the Mediterranean diet on the improvement of different cardiometabolic risk parameters. Methods: A prospective intervention study was carried out on 7034 Spanish workers. Prior to the intervention, 22 cardiometabolic risk scales were evaluated. Participants in this study were informed both orally and in writing of the characteristics and benefits of the Mediterranean diet and were given the website of the Ministry of Health, Consumption and Social Welfare of Spain, which provides advice on nutrition. Adherence to the Mediterranean diet was reinforced by sending a monthly SMS to their mobile phones. After six months of follow-up, the 22 risk scales were re-evaluated to assess changes. Means and standard deviations were calculated using Student’s t test to analyse quantitative variables. Prevalence was calculated using the Chi-square test when the variables were qualitative. Results: All the cardiometabolic risk scales studied decreased after implementing a program to improve and enhance adherence to the Mediterranean diet. The number of losses in the sample was very low, standing at 4.31%. Conclusions: The Mediterranean diet is effective in reducing all cardiovascular risk scales evaluated. The mean values and prevalence of high values of the different cardiometabolic risk scales analysed led to lower values after the implementation of the program to increase adherence to the Mediterranean diet. We observed a significant positive difference in metabolic age in both sexes. We have obtained a significant improvement in the insulin resistance index, especially in the SPISE-IR index, data that we have not found in previous publications. Easy access to the Internet and new information and communication technologies facilitate adherence to a diet and can reduce the number of losses.

5 December 2024 in Nutrients
Verified
Journal Article
Open access
PDF file
IGIgnacio Ramirez Gallegos
Ignacio Ramirez Gallegos
MAMarta Marina Arroyo
Marta Marina Arroyo
ÁGÁngel Arturo López González
Ángel Arturo López González
DVDaniela Vallejos
Daniela Vallejos
EREmilio Martinez-Almoyna Rifa
Emilio Martinez-Almoyna Rifa
JRJosé Ignacio Ramírez-Manent
José Ignacio Ramírez-Manent
Background: Metabolic age is defined as an estimation of a person’s age based on their basal metabolic rate (BMR) and other physiological health indicators. Unlike chronological age, which simply measures the number of years lived since birth, metabolic age is based on various health and fitness markers that estimate the body’s “true” biological age and can be assessed using various methodologies, including bioimpedance. The aim of this study was to evaluate how age, sex, social class, smoking habits, physical activity, and adherence to the Mediterranean diet influence metabolic age. Methods: A cross-sectional, descriptive study was conducted on 8590 Spanish workers in the Balearic Islands. A series of sociodemographic variables and health-related habits were assessed, while metabolic age was measured using bioimpedance. A metabolic age exceeding chronological age by 12 years or more was considered high. A descriptive analysis of categorical variables was performed by calculating their frequency and distribution. By applying multivariate models, specifically multinomial logistic regression, we observe that all independent variables (sex, age, social class, physical activity, mediterranean diet, and smoking) show varying levels of association with the occurrence of high metabolic age values. Among these independent variables, those showing the highest degree of association, represented by odds ratios, are physical activity, adherence to the Mediterranean diet, and social class. In all cases, the observed differences demonstrate a high level of statistical significance (p < 0.001). Results: The factors with the greatest influence were physical inactivity, with an OR of 5.07; and low adherence to the Mediterranean diet, with an OR of 2.8; followed by social class, with an OR of 2.51. Metabolic age increased with chronological age and was higher in males, with an OR of 1.38. Smoking also had a negative impact on metabolic age, with an OR of 1.19. Conclusions: Mediterranean diet is associated with a higher metabolic age. The most influential factors on metabolic age are physical activity and adherence to the Mediterranean diet, followed by the individual’s socioeconomic class. Smoking also contributes to increased metabolic age, albeit to a lesser extent.

26 July 2024 in Nutrients
Verified
Journal Article
Open access
PDF file
MAMarta Marina Arroyo
Marta Marina Arroyo
IGIgnacio Ramirez Gallegos
Ignacio Ramirez Gallegos
ÁGÁngel Arturo López González
Ángel Arturo López González
MHmaria teofila vicente herrero
maria teofila vicente herrero
DVDaniela Vallejos
Daniela Vallejos
JRJosé Ignacio Ramírez-Manent
José Ignacio Ramírez-Manent
Background: Cardiovascular diseases are the leading cause of death worldwide. Obesity and atherosclerosis are considered risk factors for this pathology. There are multiple methods to evaluate obesity, in the same way as there are different formulas to determine atherogenic risk. Since both pathologies are closely related, the objective of our work was to evaluate whether the ECORE-BF scale is capable of predicting atherogenic risk. Methods: Observational, descriptive, and cross-sectional study in which 386,924 workers from several autonomous communities in Spain participated. The association between the ECORE-BF scale and five atherogenic risk indices was evaluated. The relationship between variables was assessed using the chi-square test and Student’s t test in independent samples. Multivariate analysis was performed with the multinomial logistic regression test, calculating the odds ratio and 95% confidence intervals, with the Hosmer–Lemeshow goodness-of-fit test. ROC curves established the cut-off points for moderate and high vascular age and determined the Youden index. Results: The mean values of the ECORE-BF scale were higher in individuals with atherogenic dyslipidemia and the lipid triad, as well as in those with elevated values of the three atherogenic indices studied, with p <0.001 in all cases. As atherogenic risk increased across the five evaluated scales, the prevalence of obesity also significantly increased, with p <0.001 in all cases. In the ROC curve analysis, the AUCs for atherogenic dyslipidemia and the lipid triad were above 0.75, indicating a good association between these scales and the ECORE-BF. Although the Youden indices were not exceedingly high, they were around 0.5. Conclusions: There is a good association between atherogenic risk scales, atherogenic dyslipidemia, and lipid triad, and the ECORE-BF scale. The ECORE-BF scale can be a useful and quick tool to evaluate atherogenic risk in primary care and occupational medicine consultations without the need for blood tests.

27 March 2025 in Medicina
Verified
Journal Article
Open access
PDF file
MAMarta Marina Arroyo
Marta Marina Arroyo
IGIgnacio Ramirez Gallegos
Ignacio Ramirez Gallegos
HPHernan Paublini
Hernan Paublini
ÁGÁngel Arturo López González
Ángel Arturo López González
PTPedro Juan Tárraga-López
Pedro Juan Tárraga-López
JRJosé Ignacio Ramírez-Manent
José Ignacio Ramírez-Manent
Background and Objectives: Type 2 diabetes (T2D) and prediabetes represent major global health concerns, with obesity being a key risk factor. However, recent evidence suggests that the adipose tissue composition and distribution play a more critical role in metabolic dysfunction than the total body weight or body mass index (BMI). This study evaluates the predictive capacity of the Córdoba Equation for Estimating Body Fat (ECORE-BF) for identifying individuals at high risk of developing T2D and prediabetes. Materials and Methods: A cross-sectional study was carried out involving 418,343 Spanish workers. Body fat percentage was estimated using the ECORE-BF equation, and diabetes risk was assessed using validated predictive models, including the Finnish Diabetes Risk Score (FINDRISC), QDiabetes score (QD-score), and others. The discriminatory power of ECORE-BF in predicting T2D and prediabetes was assessed using receiver operating characteristic (ROC) curve analysis. Results: ECORE-BF showed a strong correlation with high-risk classifications across all diabetes risk scales. The area under the ROC curve (AUC) exceeded 0.95 for both men and women, demonstrating high predictive accuracy. Conclusions: Adipose tissue distribution, particularly visceral adiposity, is a central factor in metabolic dysfunction. ECORE-BF provides a cost-effective alternative for large-scale T2D and prediabetes risk assessment. Future research should explore the impact of visceral adipose tissue reduction on diabetes prevention and the integration of estimation scales into clinical and public health strategies.

27 March 2026 in Academic Journal of Health Sciences
Verified
Journal Article
Closed access
MAMari Carmen Gallegos Alvarez
Mari Carmen Gallegos Alvarez
APAina Gabriela Valiente Pizà
Aina Gabriela Valiente Pizà
IGIgnacio Ramirez Gallegos
Ignacio Ramirez Gallegos
MAMarta Marina Arroyo
Marta Marina Arroyo
AGAlberto Ramirez Gallegos
Alberto Ramirez Gallegos
JRJosé Ignacio Ramírez-Manent
José Ignacio Ramírez-Manent
Introducción: El burnout constituye un problema creciente de salud laboral vinculado a factores psicológicos, organizativos y de estilo de vida. Evidencias recientes sugieren que los patrones dietéticos, especialmente la dieta mediterránea (DM), pueden influir en la salud mental y la respuesta al estrés. Objetivo: Analizar la asociación entre la adherencia a la dieta mediterránea y el riesgo de burnout en una gran cohorte de trabajadores españoles. Métodos: Estudio transversal con 92.470 empleados (55.918 hombres y 36.552 mujeres) evaluados en reconocimientos de salud laboral entre enero de 2021 y diciembre de 2023. La adherencia a la DM se midió mediante el cuestionario MEDAS-14 y se clasificó en baja, intermedia o alta. El burnout se evaluó con el Maslach Burnout Inventory (MBI), categorizado en bajo, moderado o alto. Se aplicaron modelos de regresión logística ajustados por edad, sexo, clase social, actividad física y tabaquismo para estimar odds ratio (OR) e intervalos de confianza del 95% (IC95%). Resultados: Una alta adherencia a la DM se asoció significativamente con menor probabilidad de burnout alto (OR 0,68; IC95%: 0,62–0,75). Los análisis estratificados mostraron asociaciones más intensas en mujeres (OR 0,64; IC95%: 0,58–0,72) y en menores de 40 años (OR 0,53; IC95%: 0,45–0,62). Los resultados fueron consistentes al tratar la DM como variable continua y en análisis de sensibilidad, incluyendo la exclusión de fumadores y de personas con alta actividad física. Conclusiones: La adherencia a la dieta mediterránea se asocia de manera inversa con el riesgo de burnout en trabajadores españoles. Estos hallazgos respaldan la necesidad de integrar estrategias dietéticas, junto con intervenciones organizativas y de hábitos de vida, en los programas de bienestar laboral.