Objective: In this study, we aimed to investigate the role of peripheral blood parameters and the systemic inflammatory index (SII) in the diagnosis of hyperemesis gravidarum (HG) and whether they have a predictive value in determining the length of hospital stay and the risk of rehospitalization in HG cases. Materials and methods: In the retrospective study, pregnant women who were hospitalized due to HG (n = 112) and pregnant women who were completely healthy (n = 112) were matched for gestational age. Peripheral blood inflammation parameters of the entire study group were evaluated. The length of hospital stay and rehospitalization rate for HG cases were recorded. A total of 224 patients, 112 (50%) in the control group and 112 (50%) in the HG group were included in the study. There was a positive correlation between increased ketonuria and length of hospitalization, peripheric blood parameters, and SII. The degree of ketonuria was found to be statistically insignificant in determining the risk of rehospitalization (p = 0.927). About 28.57% (n = 32) of all HG cases were readmitted to the hospital. When the length of hospital stay was considered, SII was found to be statistically significant in hospitalizations lasting more than 2 days (p = 0.001), but not in rehospitalizations (p = 0.3). Conclusion: SII is significant in diagnosing and determining hospitalization of HG. It is sufficient to determine the length of hospital stay but not rehospitalization risk, which is an indicator of disease severity. Key words: hyperemesis gravidarum – hospitalization – inflammation markers – systemic inflammatory index

Objective: The study aimed to investigate the effect of ureteral catheter use during surgery on the outcomes of obstetric and urinary complications in patients with placenta accreta spectrum (PAS) and placenta previa. Methods: The patients who were followed up at Meram Medical Faculty Hospital of Necmettin Erbakan University between January 2016 and November 2021 and diagnosed with PAS and placenta previa were included. Patients who underwent emergency and planned surgery were grouped as those with or without an intraoperative ureteral catheter. The primary outcome was determined as the rate of urinary system damage among these groups. The number of blood transfusions, preoperative and postoperative hemoglobin values and hemoglobin changes, length of hospitalization, patients who underwent uterine-sparing surgery or hysterectomy, urinary tract injury, and wound infection were compared regarding the use of catheters. Results: A total of 122 patients were included in the study. While an intraoperative ureteral catheter was placed in 56 (45.01%) patients, it was not used in 66 (54.09%) patients. Bladder injuries were determined in 31 (55.4%) patients with a catheter and 13 (19.7%) patients without a catheter, and no other urinary system injuries were found. The incidence of bladder injury was statistically significantly higher in the group with a catheter (p=0.001). The number of transfused erythrocyte suspensions, the hemoglobin change according to the preoperative hemoglobin level, and the mean duration of hospitalization in patients with a catheter were statistically significantly greater than the group without a catheter (p=0.001). Conclusion: Ureteral catheterization did not reduce urinary damage in patients with PAS and placenta previa who underwent uterine-sparing surgery and hysterectomy. However, we believe that the insertion of a catheter increases the possibility of diagnosing intraoperative damage.

Amaç: Üçüncü düzey kliniğimizdeki nöral tüp defektli fetüslerin maternal risk faktörlerini ve postnatal kliniklerini değerlendirmeyi amaçladık.Gereç ve Yöntemler: Bu prospektif gözlemsel kohort çalışması, Mayıs 2019 – Şubat 2020 tarihleri arasında perinatoloji kliniğimize başvuran nöral tüp defektli fetusa sahip 60 gebeyi içermektedir. Katılımcılarımızın yaşı, vücut kitle indeksi ve nöral tüp defekti risk faktörleri (diyabetes mellitus, sigara, folik asit kullanımı, vs.) sorgulandı. Ultrasonografik değerlendirme ile nöral tüp defekti büyüklüğü ve yeri tespit edildi. Risk faktörleri ve nöral tüp defektli fetüslerin gebelik sonuçları değerlendirildi.Bulgular: Hastaların 5 (%8.3)’inde pregestasyonel diyabet, 30 (%50)’unda sigara kullanımı mevcuttu. Katılımcıların 26 (%43.3)’sı folik asit desteği almamıştı. Fetüslerin 34 (%56.7)’ü kız, 26 (%43.3)’sı erkek idi. Annenin vücut kitle indeksi ile nöral tüp defekti büyüklüğü arasında zayıf korelasyon saptandı (r=0.219, p=0.09). Obez hastalarda daha geniş defekt boyutu izlendi (p<0.001). Katılımcıların %60’ının ağırlığı normalden fazlaydı.Sonuç: Nöral tüp defektleri intrauterin hayatta veya doğumdan kısa süre sonra ölümcül olabilmektedir. Bu gebeliklerde erken tanı konması ve terminasyon seçeneğinin sunulması önemlidir. Ayrıca nöral tüp defektlerinin engellenebilir risk faktörlerinin belirlenmesi ve gebe adaylarının prekonsepsiyonel dönemde bilinçlendirilmesi önem arzetmektedir.

Objective: This study will evaluate whether fetal cerebroplacental ratio (CPR) can predict perinatal adverse outcomes in singleton pregnancies with mild and moderate idiopathic polyhydramnios (IP). Method: This study was designed as a prospective case–control study between January 2023 and November 2023. Pregnant women diagnosed with mild‐to‐moderate IP and low‐risk singleton pregnancies were included in the study. In all cases, umbilical artery (UA) and middle cerebral artery (MCA) pulsatility indices (PIs) were measured at 36–40 weeks of gestation, and CPR was calculated. The group with polyhydramnios was divided into two parts according to whether the CPR value was below 1.08 or 1.08 and above. Perinatal outcomes of all groups were compared. Results: A total of 140 patients were included in the study. Seventy of these were IP cases, and 70 were low‐risk pregnant women. UA PI in the IP group was not statistically different from that in the low‐risk group, but MCA PI and CPR were significantly lower in the IP group ( P = 0.07, P = 0.001, and P = 0.004, respectively). IP cases were divided into a low group (<1.08, n = 18) and a normal group (≥1.08, n = 52) according to the CPR value. Cesarean section rates due to fetal distress were significantly higher in the low‐CPR group ( n = 8 [44.4%] vs 5 [9.6%], P = 0.001). In the low‐CPR group, 5‐min Apgar <7, and neonatal intensive care unit (NICU) admission rates were significantly higher ( P = 0.045 and P = 0.001, respectively). Conclusion: It is encouraging that in cases with mild‐to‐moderate IP, low CPR predicts emergency delivery due to fetal distress, a low Apgar score at 5 min, and NICU admission.