A novel and facile chiral sensing platform has been designed for electrochemical enantiomer recognition based on the coupling of three-dimensional-graphene with hydroxypropyl-β-cyclodextrin (3D-G/HP-β-CD).

A multifunctional targeted drug delivery platform (CDHA–MGO) has been successfully constructed by grafting β-cyclodextrin–hyaluronic acid polymers (CDHA) to Fe₃O₄–graphene oxide (MGO). The obtained CDHA–MGO nanocomposite has good water-dispersibility, easy magnetic separation, high near-infrared (NIR) photothermal heating, and excellent biocompatibility. The β-cyclodextrin-hyaluronic acid polymers efficaciously enhance the doxorubicin (DOX) loading amount up to 485.43 mg·g⁻¹. Meanwhile, the Fe₃O₄–graphene oxide provides a facile photothermal response mechanism to handle the NIR-triggered release of DOX in weak acidic solvent environments. Significantly, the DOX-loaded nanocomposite (DOX@CDHA–MGO) has displayed CD44 receptor-mediated active targeting recognition and chemo-photothermal synergistic therapy of hepatoma cells. These findings suggest that the as-prepared drug delivery platform would be of valuable potential for cancer-targeted photo-chemotherapy.

β-Cyclodextrin polymer functionalized magnetic nanoparticles (CDP-MNPs) were prepared with a one-step co-precipitation method by anchoring a carboxymethyl-β-cyclodextrin polymer (CDP) onto the surface of Fe₃O₄ magnetic nanoparticles (MNPs). The CDP-MNPs possess the fascinating features of superparamagnetism and adsorption properties, which are favorable for the purpose of removing bisphenol A and resorcin. The maximum adsorption capacity for bisphenol A could reach values up to 74.63 mg g⁻¹ at 25 °C, which is higher than those of previously reported magnetic adsorbents. Moreover, for the removal of resorcin by CDP-MNPs, the maximum uptake amounted to 114.91 mg g⁻¹ under the same conditions. The adsorption kinetics and isotherm data fitted well with a pseudo-second-order kinetic model and the Langmuir isotherm, respectively. The CD polymer grafted onto the MNPs enhanced the adsorption capacity because of the host–guest interaction of cyclodextrin and the hydrogen bonding of the polymer network with the phenolic compounds. Additionally, a good recyclability of the CDP-MNPs was observed over three usage cycles, with only a slight decline in adsorption capability.