In this paper, thermal mixing characteristics of two miscible fluids in a T-shaped microchannel are investigated theoretically, experimentally, and numerically. Thermal mixing processes in a T-shaped microchannel are divided into two zones, consisting of a T-junction and a mixing channel. An analytical two-dimensional model was first built to describe the heat transfer processes in the mixing channel. In the experiments, de-ionized water was employed as the working fluid. Laser induced fluorescence method was used to measure the fluid temperature field in the microchannel. Different combinations of flow rate ratios were studied to investigate the thermal mixing characteristics in the microchannel. At the T-junction, thermal diffusion is found to be dominant in this area due to the striation in the temperature contours. In the mixing channel, heat transfer processes are found to be controlled by thermal diffusion and convection. Measured temperature profiles at the T-junction and mixing channel are compared with analytical model and numerical simulation, respectively.

Droplet coalescence is one of the most attractive manipulation schemes in droplet-based microfluidic systems, which enables droplet-based functions such as mixing and microreactor to be achieved in lab-on-a-chip applications. This paper systematically presents an overview on techniques used for droplet coalescence in microfluidic systems. In this paper, techniques employed for droplet coalescence are categorized as passive and active types. The basic theory and mechanism behind these techniques are also presented.Full Tex

Microfluidic technology has emerged from the MEMS (Micro-Electro-Mechanical System)-technology as an important research field. During the last decade, various microfluidic technologies have been developed to open up a new era for biological studies. To understand the function of single cells, it is very important to monitor the dynamic behavior of a single cell in a living environment. Cell trapping in single cell analysis is urgently demanded There have been some review papers focusing on drug screen and cell analysis. However, cell trapping in single cell analysis has rarely been covered in the previous reviews. The present paper focuses on recent developments of cell trapping and highlights the mechanisms, governing equations and key parameters affecting the cell trapping efficiency by contact-based and contactless approach. The applications of the cell trapping method are discussed according to their basic research areas, such as biology and tissue engineering. Finally, the paper highlights the most promising cell trapping method for this research area.

The tip gap existing between the blade tip and casing can give rise to tip leakage flow and interfere with the main flow, which causes unstable flow characteristics and intricate vortex in the passage. Investigation on the tip clearance effect is of great important due to its extensive applications in the rotating component of pumps. In this study, a scaling axial flow pump used in a south-north water diversion project with different sizes of tip clearances was employed to study the tip clearance effect on tip leakage vortex (TLV) characteristics. This analysis is based on a modified turbulence model. Validations were carried out using a high-speed photography technique. The tip clearance effect on the generation and evolution of TLV was investigated through the mean velocity, pressure, and vorticity fields. Results show that there are two kinds of TLV structures in the tip region. Accompanied by tip clearance increasing, the viscous loss in the tip area of the axial flow pump increases. Furthermore, the tip clearance effect on pressure distribution in the blade passage is discussed. Beyond that, the tip clearance effect on vortex core pressure and cavitation is studied.