Laser Powder Directed Energy Deposition (LP-DED) is an advanced additive manufacturing process that uses a focused laser beam to melt and fuse powder material onto a substrate. This technology enables the production of complex metal components with high precision and material efficiency. The properties of the powder feedstock are highly important and have been extensively studied in the literature. Powder size distribution and particle shape have been identified as key factors influencing the flowability, and it is imperative that nozzle designs take these into account for optimum material delivery. The laser–powder interaction, where the laser energy influences the melting behavior, as well as nozzle designs, have been highlighted in both historical and the more recent laser cladding literature. Finally, a comprehensive analysis of fluid dynamic simulations of the powder particles and their interaction with the nozzle design is provided.

Three-dimensional printing technologies are becoming increasingly attractive for their versatility; the geometrical customizability and manageability of the final product properties are the key points. This work aims to assess the feasibility of producing radiopaque filaments for fused deposition modeling (FDM), a 3D printing technology, starting with zinc oxide (ZnO) and polylactic acid (PLA) as the raw materials. Indeed, ZnO and PLA are promising materials due to their non-toxic and biocompatible nature. Pellets of PLA and ZnO in the form of nanoparticles were mixed together using ethanol; this homogenous mixture was processed by a commercial extruder, optimizing the process parameters for obtaining mechanically stable samples. Scanning electron microscopy analyses were used to assess, in the extruded samples, the homogenous distribution of the ZnO in the PLA matrix. Moreover, X-ray microtomography revealed a certain homogenous radiopacity; this imaging technique also confirmed the correct distribution of the ZnO in the PLA matrix. Thus, our tests showed that mechanically stable radiopaque filaments, ready for FDM systems, were obtained by homogenously loading the PLA with a maximum ZnO content of 6.5% wt. (nominal). This study produced multiple outcomes. We demonstrated the feasibility of producing radiopaque filaments for additive manufacturing using safe materials. Moreover, each phase of the process is cost-effective and green-oriented; in fact, the homogenous mixture of PLA and ZnO requires only a small amount of ethanol, which evaporates in minutes without any temperature adjustment. Finally, both the extruding and the FDM technologies are the most accessible systems for the additive manufacturing commercial apparatuses.