Aim The Naples prognostic score (NPS) simultaneously evaluates inflammation and malnutrition, which are two main factors that play a role in the pathophysiology and prognosis of heart failure (HF). In this study, we aimed to examine the relationship of NPS with in-hospital mortality of hospitalized patients with a diagnosis of HF. Material and Methods   A total of 496 hospitalized HF patients included in this study. The patients were divided into two groups as deceased and living. The clinical and demographic characteristics of each patient were recorded. NPS of each patient was calculated. Results   NPS was significantly higher in the deceased group compared to the living group (3.6±0.61, 3.21±0.97, respectively; p=0.003). According to multivariate regression analysis: NPS (OR: 1.546, 95 % CI: 1.027–2.327; p=0.037), systolic blood pressure (OR: 0.976, 95 % CI: 0.957–0.995; p=0.015), and white blood cell count (OR: 1.072, 95 % CI: 1.007–1142; p=0.03) are independent predictors for in-hospital mortality in HF patients. Conclusion This study demonstrated a strong correlation between NPS and mortality in HF. This new score can be used to predict the prognosis of HF as it shows both the level of inflammation and nutrition.

Objective: To evaluate left atrial (LA) deformation parameters strain (S)/strain rate (SR) and time to peak S/SR obtained by two-dimensional speckle tracking echocardiography (2D-STE) in patients with hypertension for three LA mechanical phases and to compare them with the same indices in the control subjects. Methods: Fifty-five patients with hypertension (HT) and 29 healthy controls were included in the study. All patients had normal LA poster-anterior diameter, LA and left ventricular ejection fractions (LVEF >50%) in two-dimensional echocardiography (2-DE). The peak S/SR values (PS/PSR), the time to peak S/SR (TPS/TPSR) were measured using the 12-segment model for the left atrium during contractile (CP) reservoir (RP) and conduit period (COP) of the LA cycle. Results: For two periods (RP and COP), all of the PS and PSR values were significantly lower in hypertensive patients with preserved LAEF and LVEF compared to those in the controls, except for the CP. Similarly, hypertensive patients had significantly higher TPS and TPSR than those in the controls for the RP and COP in the LA wall, except for the CP. Conclusion: LA mechanical function was impaired in hypertensive patients with preserved LA and LV ejection fraction compared to the controls. Although the PS and PSR were decreased for the RP and COP of LA mechanical phases, the TPS/TPSR were prolonged in the HT patients compared to the controls. This might be additional diagnosis criteria to detect the LA myocardial dysfunction and might be a predisposing factor for atrial arrhythmia formation in the hypertensive patients.

Background Acute coronary syndrome (ACS) is the most common subtype of coronary artery disease (CAD). It is one of the main reasons affecting the expected life expectancy and quality of life. Objetives In this study, we aimed to investigate the relationship between major adverse cardiac events (MACE) and Hemoglobin (Hb)/Red cell distribution width (RDW) in long-term follow-up after ACS. Methods A total of 1,146 ACS patients were included in the study, being classified according to the type of myocordial [...] Abstract Background Acute coronary syndrome (ACS) is the most common subtype of coronary artery disease (CAD). It is one of the main reasons affecting the expected life expectancy and quality of life. Objetives In this study, we aimed to investigate the relationship between major adverse cardiac events (MACE) and Hemoglobin (Hb)/Red cell distribution width (RDW) in long-term follow-up after ACS. Methods A total of 1,146 ACS patients were included in the study, being classified according to the type of myocordial

Renal artery thromboembolism (RATE) is an uncommon complication of renal arteries from heart chamber. Although there is no treatment protocol prescribed with guidelines, thrombolytic agents such as rt-PA are frequently used. Unfortunately, current thrombolytic agent application protocol in treatment for the RATE is used in acute myocardial infarction or acute pulmonary embolism. In this protocol, 0.9–1.0% cerebral and 4–13% noncerebral hemorrhages are seen. In contrast to this protocol, we aimed to present a case of RATE, in which we applied low-dose, slow-infusion thrombolytic therapy, and we have not observed any complication such as cerebral and noncerebral hemorrhage.

Objectives: This study aimed to investigate the relationship between the anticoagulation and risk factors in atrial fibrillation (ATRIA) score and initial stroke severity in patients with acute ischemic stroke of varying etiologies, including atrial fibrillation (AF), large-artery atherosclerosis, and undetermined origin. Methods: In this prospective observational study, 416 patients admitted with acute ischemic stroke between June 2022 and December 2024 were analyzed. Stroke severity was assessed using the National Institutes of Health Stroke Scale (NIHSS), and patients were categorized into two groups: mild-to-moderate (NIHSS ≤ 15) and moderate-to-severe/severe (NIHSS > 15). Pre-admission ATRIA scores were calculated based on demographic and clinical parameters. Multivariable logistic regression was performed to assess the association between ATRIA scores and stroke severity. Results: Patients with more severe strokes had significantly higher ATRIA scores (median 8.5 vs. 5.0, p < 0.001). AF was more frequent in the severe group (44.8% vs. 31.3%, p = 0.037). In multivariable analysis, each one-point increase in the ATRIA score was independently associated with a 1.82-fold increase in the odds of severe stroke (OR 1.823, 95% CI 1.568–2.119, p < 0.001). High ATRIA scores (>6) were associated with an 11.7-fold increased risk of severe stroke (OR 11.692, 95% CI 5.636–24.255, p < 0.001), independent of stroke etiology, ejection fraction, and inflammatory markers. Conclusions: The ATRIA score is independently associated with initial stroke severity across diverse ischemic stroke etiologies. It may serve as a simple, practical tool for early risk stratification in the acute setting, regardless of AF status. Further studies are warranted to confirm its utility in guiding early management and prognosis.