This study was carried out to investigate the differentiation of mucinous borderline ovarian tumor from mucinous ovarian carcinoma using magnetic resonance imaging.

Objective To analyze the serum markers for the early diagnosis of intestinal anastomotic leak (AL) after the gyne-oncological operations. Methods Between September 2017 and March 2021, patients with an intestinal anastomosis performed during the gyne-oncological surgeries were identified from a tertiary center in Turkey. As the local guideline of the clinic, all these patients were followed by measuring serum samples including procalcitonin (PCT) and C-reactive protein (CRP) on postoperative day (POD) 1 through the day of discharge or the day of re-operation for AL. Results 12.5% (5/40) of the patients suffered an AL and 4 of them were re-operated. The mean albumin values on POD 3-4 and the mean platelet values on POD 1 were lower in the AL group (p0.05), median PCT values (ng/mL) on POD 8-10 were higher in the AL group compared with no leak group. The best cutt-off point for PCT on POD 9 was determined to be 0.11 ng/mL (AUC: 0.917, Sensitivity = %100.0, specifity = %66.7, positive predictive value = %66.7, negative predictive value = %100.0). Conclusion Serum PCT and CRP concentrations were not found to be helpful for the early diagnosis of AL in patients operated for gyne-oncological malignancies. Low levels of albumin and platelets in the first days after the operation may be clue for a possible AL.

Objective: This research aimed to investigate whether the proportion of the serous carcinoma component influences the prognosis of patients diagnosed with mixed-type endometrial carcinoma. Methods: Based on the relative percentage of the serous component, patients were grouped into two categories: ≤50% and >50%. These groups were analyzed and compared with respect to demographic characteristics (age, body mass index, and parity), and histopathological features (grade, level of myometrial invasion, lymphovascular space invasion, tumor size, and FIGO stage). Cox regression and Kaplan–Meier survival analyses were used for the evaluation of overall survival (OS), disease-free survival (DFS), recurrence, and mortality rates. Results: Individuals with a serous component exceeding 50% had significantly reduced DFS and OS (DFS: 42.9 ± 25.9 vs. 60.2 ± 25.9 months, p = 0.04; OS: 47.9 ± 24.8 vs. 68.7 ± 20.5 months, p = 0.007). Multivariate analysis identified age, deep myometrial invasion, and serous predominance (>50%) as independent predictors of poorer DFS and OS (p < 0.05). Tumor size and lymphovascular space invasion (LVSI) did not have statistically significant correlations with survival outcomes. Conclusion: Although rare, mixed-type endometrial carcinoma with a dominant serous component appears to exhibit more aggressive behavior and poorer survival. The proportion of serous histology should be regarded as a critical prognostic indicator during clinical assessment and treatment planning.