Background/Objectives: Dental caries and periodontal diseases are the most common illnesses in the oral cavity and represent a public health concern globally. In recent decades, diverse studies showed that Kefir, a traditional beverage that can be milk- or water-based, contains a complex microbial community and has health benefits. The goal of this review was to update the current knowledge of kefir consumption and its impact on oral health. Methods: The search of a combination of keywords—kefir; dental caries; probiotics; microbiota; periodontal diseases; biofilm; and oral health—was conducted using PubMed, Google Scholar, and Web of Science databases for studies in human subjects. Discussion: The research suggests that kefir consumption may aid in decreasing counts of microorganisms typically associated with oral illness. Conclusions: Kefir has the potential to inhibit certain oral pathogens and reduce biofilm formation by promoting diversity within the oral microbiota, suggesting that kefir could be a promising adjuvant treatment for dental caries and periodontal diseases by improving oral health.

P53 is a tumor suppressor involved in cell-cycle regulation and DNA repair. Studies have shown that altered p53 expression in oral squamous cell carcinoma (OSCC) is associated with a poor prognosis and increased tumor aggressiveness, suggesting it could be considered a potential prognostic marker. A search was performed using keywords such as oral squamous cell carcinoma, TP53, and p53 therapies in the PubMed and Web of Science databases, with a timeframe from 2020 to 2025. In this review, we examined various therapies targeting p53 that have been proposed in recent years. These therapies have been tested in vitro, in vivo, and in some cases, through clinical trials. Their goal is to restore the conformation and activity of mutated p53 by identifying small molecules that restore p53 function and eliminate mutated cells. Although some of these therapies show promising results, further clinical studies are needed to assess their efficacy and safety in OSCC patients.