Diana I. Alves

Dr. Diana I. Alves

orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 February 2024 in Frontiers in Environmental Science
Verified
Journal Article
Open access
DADiana I. Alves
Diana I. Alves
MBMariana Barreiros
Mariana Barreiros
Raul FangueiroRaul Fangueiro
Raul Fangueiro
DFDiana Ferreira
Diana Ferreira
Each year, millions of tons of clothing are both produced and discarded, exerting a substantial impact on the environment and public health. Even when textile waste is disposed of in landfills, it persistently adds to pollution in the air, water, and soil. This review explores the diverse implications of textile waste, examining circular economy principles and highlighting opportunities for transforming textile waste into eco-friendly materials. This review highlights opportunities to repurpose textile waste into new products, aligning with the principles of a circular economy. The discussed materials, such as cotton, wool, polyester, nylon, and kevlar, can be utilized in various industries, including construction, non-woven, furniture, carpet, agriculture, and paper. The alternative materials presented offer excellent mechanical, thermal, and acoustic properties, providing sustainable alternatives in applications ranging from civil construction to insulation and structure reinforcement, minimizing environmental impact. Green material alternatives enhance cost-effectiveness in constructing eco-friendly buildings, reducing the need for extracting new raw materials and minimizing the carbon footprint. It is expected that research on opportunities for recovering textile waste will soon intensify, leading to the implementation of these new eco-friendly products.

29 March 2023 in Molecules
Verified
Journal Article
Open access
PDF file
DADiana I. Alves
Diana I. Alves
JAJoana C. Araújo
Joana C. Araújo
Raul FangueiroRaul Fangueiro
Raul Fangueiro
DFDiana Ferreira
Diana Ferreira
Cancer remains one of the most challenging health problems worldwide, and localized therapeutic approaches based on micro/nanofibers have shown potential for its treatment. Micro/nanofibers offer several advantages as a drug delivery system, such as high surface area, tunable pore size, and sustained release properties, which can improve drug efficacy and reduce side effects. In addition, functionalization of these fibers with nanoparticles can enhance their targeting and therapeutic capabilities. Localized delivery of drugs and/or other therapeutic agents via micro/nanofibers can also help to overcome the limitations of systemic administration, such as poor bioavailability and off-target effects. Several studies have shown promising results in preclinical models of cancer, including inhibition of tumor growth and improved survival rates. However, more research is needed to overcome technical and regulatory challenges to bring these approaches to clinical use. Localized therapeutic approaches based on micro/nanofibers hold great promise for the future of cancer treatment, providing a targeted, effective, and minimally invasive alternative to traditional treatments. The main focus of this review is to explore the current treatments utilizing micro/nanofibers, as well as localized drug delivery systems that rely on fibrous structures to deliver and release drugs for the treatment of cancer in a specific area.

7 June 2024 in Journal of Environmental Management
Verified
Journal Article
Open access
DADiana I. Alves
Diana I. Alves
ÓCÓscar Samuel Novais Carvalho
Óscar Samuel Novais Carvalho
Nuno A. T. C. FernandesNuno A. T. C. Fernandes
Nuno A. T. C. Fernandes
LCLivia Tavares Cosentino
Livia Tavares Cosentino
Adilson Campos Paula JuniorAdilson Campos Paula Junior
Adilson Campos Paula Junior
DFDiana Ferreira
Diana Ferreira
The footwear industry significantly impacts the environment, from raw material extraction to waste disposal. Transforming waste into new products is a viable option to mitigate the environmental consequences, reducing the reliance on virgin raw materials. This work aims to develop thermal and acoustic insulation materials using polyester waste from footwear industry. Two nonwoven and two compressed nonwoven structures, comprising 80% polyester waste and 20% commercial recycled polyester (matrix), were produced. The materials were created through needle-punching and compression molding techniques. The study included the production of sandwich and monolayer nonwoven structures, which were evaluated considering area weight, thickness, air permeability, mechanical properties, morphology using field emission scanning electron microscopy, and thermal and acoustic properties. The nonwoven samples presented high tensile strength (893 kPa and 629 kPa) and the highest strain (79.7% and 73.3%) and compressed nonwoven structures showed higher tensile strength (2700 kPa and 1291 kPa) but reduced strain (25.8% and 40.8%). Nonwoven samples showed thermal conductivity of 0.041 W/K.m and 0.037 W/K.m. Compressed nonwoven samples had higher values at 0.060 W/K.m and 0.070 W/K.m. While the sample with the highest conductivity exceeds typical insulation levels, other samples are suitable for thermal insulation. Nonwoven structures exhibited good absorption coefficients (0.640-0.644), suitable for acoustic insulation. Compressed nonwoven structures had lower values (0.291-0.536), unsuitable for this purpose. In summary, this study underscores the potential of 100% recycled polyester structures derived from footwear and textile industry waste, showcasing remarkable acoustic and thermal insulation properties ideal for the construction sector.

Verified
Journal Article
Open access
PDF file
Nuno A. T. C. FernandesNuno A. T. C. Fernandes
Nuno A. T. C. Fernandes
DADiana I. Alves
Diana I. Alves
DFDiana Ferreira
Diana Ferreira
MMMaria Monteiro
Maria Monteiro
AAAna Arieira
Ana Arieira
ÓCÓscar Samuel Novais Carvalho
Óscar Samuel Novais Carvalho
Medical phantoms are essential to imaging calibration, clinician training, and the validation of therapeutic procedures. However, most ultrasound phantoms prioritize acoustic realism while neglecting the viscoelastic and anisotropic properties of fibrous soft tissues. This gap limits their effectiveness in modeling realistic biomechanical behavior, especially in wave-based diagnostics and therapeutic ultrasound. Current materials like gelatine and agarose fall short in reproducing the complex interplay between the solid and fluid components found in biological tissues. To address this, we developed a soft, anisotropic composite whose dynamic mechanical properties resemble fibrous biological tissues such as skin and skeletal muscle. This material enables wave propagation and vibration studies in controllably anisotropic media, which are rare and highly valuable. We demonstrate the tunability of damping and stiffness aligned with fiber orientation, providing a versatile platform for modeling soft-tissue dynamics and validating biomechanical simulations. The phantoms achieved Young’s moduli of 7.16–11.04 MPa for skin and 0.494–1.743 MPa for muscles, shear wave speeds of 1.51–5.93 m/s, longitudinal wave speeds of 1086–1127 m/s, and sound absorption coefficients of 0.13–0.76 dB/cm/MHz, with storage, loss, and complex moduli reaching 1.035–6.652 kPa, 0.1831–0.8546 kPa, and 2.138–10.82 kPa. These values reveal anisotropic response patterns analogous to native tissues. This novel natural fibrous composite system affords sustainable, low-cost ultrasound phantoms that support both mechanical fidelity and acoustic realism. Our approach offers a route to next-gen tissue-mimicking phantoms for elastography, wave propagation studies, and dynamic calibration across diverse clinical and research applications.

7 January 2026 in Textiles
Verified
Journal Article
Open access
PDF file
ASAna Santos
Ana Santos
SRSofia Rocha
Sofia Rocha
Nuno A. T. C. FernandesNuno A. T. C. Fernandes
Nuno A. T. C. Fernandes
DADiana I. Alves
Diana I. Alves
DFDiana Ferreira
Diana Ferreira
ÓCÓscar Samuel Novais Carvalho
Óscar Samuel Novais Carvalho
Tissue-mimicking phantoms that accurately replicate human tissue are crucial for validating and optimizing elastography systems and developing new treatment methods. The use of waste-based fibrous structures has the dual benefits of waste reduction and economic viability, mitigating the environmental consequences associated with the textile industry and, thus, posing a particularly interesting avenue of research in today’s ever-more environmentally conscious society. This work explores the development of elastography phantoms through the use of textile waste for sustainable valorization. Two cotton-short fiber-based and two polyester-nonwoven-based phantoms were produced by impregnating these textile structures with animal-origin gelatin. These materials were characterized by scanning electron microscopy (SEM), revealing that the diameter of the waste-based fibers (15.28 ± 6.18–22.40 ± 5.78 μm) falls within the typical size range of scatterers used in acoustic phantoms. It was observed that these fibers provided phantoms with intrinsic acoustic scattering properties, resulting in ultrasound images similar to those obtained in biological tissues. Shear wave elastography (SWE) was used to assess the stiffness of the phantoms, which produced realistic ultrasound images with shear wave speed (SWS) values ranging from 1.87 m s−1 to 8.39 m s−1, closely resembling those in different anatomical structures. This research presents an innovative methodology for producing low-cost and sustainable tissue-mimicking materials, underscoring the potential of textile industry waste for phantom production.

30 May 2026 in Construction and Building Materials
Verified
Journal Article
Closed access
NLNannan Li
Nannan Li
Zhiyou JiaZhiyou Jia
Zhiyou Jia
SCSandra Cunha
Sandra Cunha
DADiana I. Alves
Diana I. Alves
DFDiana P. Ferreira
Diana P. Ferreira
Jose AguiarJose Aguiar
Jose Aguiar