Background/Objectives: Few studies have comprehensively examined dental anomalies in adolescents with genetic syndromes. This study aimed to assess their prevalence, types, and clinical patterns in a diverse sample of genetically confirmed cases. Methods: We conducted a retrospective cross-sectional study of 213 patients aged 12 to 18 years with various genetic syndromes, using clinical data originally collected between 2011 and 2014 at a tertiary center. Clinical examinations were complemented by radiographs when available. Anomalies were categorized by type, and a disproportionality analysis (Rate of Occurrence Ratio, ROR) quantified risk relative to syndrome representation. Results: Dental anomalies were present in 68% of adolescents. The most common findings were hypodontia, taurodontism (9%), and enamel hypoplasia (8%). Nearly half of the patients exhibited combined patterns, with hypodontia–taurodontism as the most characteristic combination (14%). Prevalence was particularly high in trisomy-based (80%) and osteogenesis-related (100%) syndromes. Down syndrome showed the strongest association (ROR 3.95; 95% CI: 2.15–7.25), while some conditions such as Turner, Ehlers-Danlos, and Tuberous sclerosis displayed significantly lower rates. Conclusions: Dental anomalies are both highly prevalent and patterned in adolescents with genetic syndromes. Their co-occurrence and specificity suggest that they may serve as useful diagnostic markers in syndromic evaluation.

Background/Objectives: Phytotherapy, the use of plant-derived bioactive compounds for therapeutic purposes, has gained increasing attention in dentistry as a natural, well-tolerated, and culturally acceptable adjunct to conventional treatments. In pediatric dentistry, its potential relevance lies in its antimicrobial, anti-inflammatory, and antioxidant properties, which may support oral health, caries prevention, pulp vitality, and gingival health. This narrative review aimed to summarize the current clinical evidence regarding the application of phytotherapeutic agents in pediatric oral care. Methods: A narrative review was conducted according to SANRA guidelines, including clinical studies on plant-based products used for preventive or therapeutic purposes in children and adolescents. Results: Forty-three clinical studies met the inclusion criteria. The most commonly investigated agents included licorice, green tea, cocoa husk, cranberry, pomegranate, Aloe vera, and miswak. These agents demonstrated antimicrobial activity against cariogenic bacteria, reduction in plaque and gingival indices, and favorable healing in pulp therapies. In endodontics, Aloe vera-derived acemannan and Ankaferd Blood Stopper^® showed outcomes comparable to conventional materials, while pomegranate and apple cider vinegar exhibited partial antibacterial effects as irrigants. Conclusions: Phytotherapy shows promise as a complementary approach in pediatric dentistry, contributing to caries prevention, gingivitis control, and pulp healing. However, current evidence remains limited by small sample sizes, short-term follow-ups, and heterogeneity in formulations. Further trials are required to confirm efficacy, ensure safety, and standardize phytotherapeutic applications in pediatric oral care.

Background/Objectives: Polymethyl methacrylate (PMMA)-based acrylic materials are widely used in dentistry, but they are not completely biologically inert and have been associated with hypersensitivity and allergic reactions in both patients and dental personnel. This narrative review aimed to synthesize the available evidence on (meth)acrylate-related hypersensitivity reactions in dentistry, with an emphasis on clinical manifestations, immunological mechanisms, and risk factors. Methods: A structured literature search was conducted in PubMed, Web of Science, and Scopus (15 August–1 September 2026), following the SANRA (Scale for the Assessment of Narrative Review Articles) guideline. After screening 408 records, 17 core articles were selected and grouped into four thematic categories: prevalence and clinical relevance, molecular and immunological mechanisms, clinical manifestations in patients, and occupational sensitization in dental personnel. Results: Confirmed (meth)acrylate sensitization ranges from 1.4% to 8% depending on population and testing methodology, remaining lower than metal allergy but clinically relevant. Haptenization through covalent binding of electrophilic monomers to host proteins underlies sensitization, while sublethal HEMA (2-hydroxyethyl methacrylate) exposure can induce measurable cellular stress independent of overt cytotoxicity. Patient presentations range from localized contact stomatitis to acute facial swelling, whereas dental personnel, particularly dental technicians, show disproportionately high occupational incidence rates. Testing restricted to HEMA alone may miss a substantial proportion of sensitized individuals. Conclusions: (Meth)acrylate hypersensitivity, although relatively uncommon, warrants increased diagnostic vigilance, broader patch-test panels, and improved occupational preventive measures. The current literature remains methodologically heterogeneous, underscoring the need for standardized testing series and larger prospective studies.

Introduction: The most common allergens in prosthetic materials are acrylates and metals. Allergy to acrylates and methacrylates is a rare cause of stomatitis, because dentures contain acrylate in polymerized, non-sensitizing form. Background and Objectives: This study aims to report the management of the case of a patient allergic to different materials, which requires prosthetic treatment. Materials and Methods: A 65-year-old woman requested a complete prosthetic rehabilitation. The difficulty of the treatment was to choose the type of prostheses according to the allergies presented by the patient. Results: The removable partial denture, made of Biodentaplast (Bredent, Germany), a combination of classic acrylic and elastic prosthesis, satisfies both aesthetically and functionally. During the evaluation and control at 6 and 12 months, it was found the good preservation of the restorations, the normal appearance of the oral cavity structures and the functionality of the prostheses Conclusions: For the success of the treatment it is important to know the medical and dental history of the patient in establishing the prosthetic treatment plan. The peculiarity of this case lies in the fact that the patient's allergies determine the change of the prosthetic treatment plan, in the sense that a simple fixed pros-thesis becomes a mobile prosthesis made of materials chosen in accordance with the patient's condition.