Among many environmental factors nutrition is paramount, permanently and exclusively affecting in multidisciplinary mode on the biological and social essence of the human body. Therefore, this article describes the results of the actual supply of people aged of 60-89 years taking into account their eating habits associated with age-related changes in the gastrointestinal tract and metabolism. The study involved 611 respondents aged of 60-89 years, including men (23.9%) and women - 76.1%, living in Astana, the average age accounts of 73 ± 0.41years. The actual food was studied by frequency and a 24-hour simulation, recommended by the WHO for epidemiological studies. In assessing the adequacy of the supply of the reference values there were taken norms of physiological requirements in energy and nutrients for the population of gerontological groups of the Republic of Kazakhstan, as well as the norms of consumption of micronutrients on a scale of FAO / WHO. The study of the actual nutrition of the category of persons of Astana showed the diet of elderly people to be consisted of foods containing mostly protein and animal fats and digestible carbohydrates, while two latters were characterized by an excess of saturated fatty acids, the lack of polyunsaturated fatty acids, a high level of simple consumption carbohydrates from refined foods such as sugar, refined cereals, flour and poly- micronutrient failure of the nutrition on vitamins (deficiency of vitamin D, a, B1, E, C, biotin, folic and pantothenic acid) and minerals (calcium deficiency, potassium).

The aim of this study was to assess bone health in individuals over 60 years of age in Kazakhstan, focusing on the relationship between osteoporosis, body mass index (BMI), body composition, and nutritional factors. This study included 1961 participants, consisting of 1620 women and 341 men, aged 60 to 89. Bone strength was assessed using quantitative ultrasound of the calcaneus, while fracture risk was assessed with the FRAX tool. Osteoporosis was detected in 20.2% of women and 15.2% of men, and osteopenia affected 59.8% of women and 58.4% of men. A total of 73.7% of the participants were overweight, 38.2% were pre-obese, and 35.5% were obese. The results of the study emphasise that, in addition to classic nutrients (calcium, vitamin D, protein), a number of trace elements and vitamins (selenium, iodine, zinc, vitamin B6, phytosterols) also play a significant, possibly indirect, role in bone metabolism. An inverse correlation was observed between BMI and osteoporosis prevalence; with a decrease in BMI, the incidence of osteoporosis increased (women: χ² = 26.0, df = 2, p < 0.001; men: χ² = 4.29, df = 2, p < 0.014; total sample: χ² = 32.3, df = 2, p < 0.001), thus confirming that excess body fat exerts a protective effect on bone health. Significant risk factors for osteoporosis included age, height, and weight. A link was found between the age of first osteoporosis onset and BMI (from 65 to 72.14 years). This confirms the value of FRAX for accurately assessing fracture risk and developing personalised recommendations based on anthropometric and dietary characteristics. Future longitudinal research is warranted to validate these results and further elucidate the underlying mechanisms, including the predictive power of novel anthropometric parameters such as the Body Roundness Index and Body Shape Index.

Морковь (Daucus carota L.) - важная сельскохозяйственная культура семейства Apiaceae, имеющая высокую пищевую и биологическую ценность. Корнеплоды моркови содержат широкий спектр питательных веществ и биологически активных соединений, включая каротиноиды и флавоноиды. В данной статье представлен аналитический обзор современных научных данных о полезных свойствах моркови, включая ее антиоксидантное, противовоспалительное и онкопротекторное действия, а также влияния на иммунную систему. Отмечена высокая профилактическая ценность моркови как для взрослых, так и для детей. Регулярное потребление моркови в составе ежедневного рациона, в том числе в виде функциональных продуктов и натуральных добавок, способствует укреплению здоровья и снижению риска развития ряда хронических заболеваний.

This article presents the Health REVIVE Model, an innovative physical education and health framework developed at Astana Medical University for students in special medical groups. The aim of the study is the development of an innovative physical education and health model of physical education classes for students with disabilities based on the interdisciplinary experience of Astana Medical University. The research methodology includes a comprehensive approach: data analysis and synthesis, comparative analysis, structural-functional modeling, and a cross-sectional design (sociological survey, retrospective analysis of medical records, and pedagogical experiment). Results. The model addresses systemic challenges in physical education and aims to boost motivation and improve the quality of life for students with health limitations. It integrates diagnostics, training, practical sessions, and evaluation to provide a flexible, interdisciplinary approach tailored to individual medical needs. Key advantages include interdepartmental collaboration, the synergy of professional competencies, and the creation of optimal conditions for students' physical development. The model emphasizes comprehensive support and individualized adaptation of physical activities to enhance physical fitness while accounting for students' health conditions. Conclusions. The observational study revealed the urgent need for such an interdisciplinary and adaptive approach. The Health REVIVE Model is structured around four components: diagnostic, target, process, and reflexive-evaluative. This structure ensures effective monitoring and modification of physical activity programs for students of special medical groups. The scientific novelty of the model lies in its focus on forming an individual’s physical culture as an integrative quality, preparing graduates for health-preserving professional activities and active social participation.

Background: Circulating α-Klotho is a longevity-related protein with anti-inflammatory and cytoprotective functions. Evidence on its relationship with individual leukocyte populations is limited, while eosinophils may have both inflammatory and tissue-homeostatic roles. We examined the association of serum α-Klotho with absolute and relative eosinophil measures in older adults. Methods: This cross-sectional analysis included 502 community-dwelling adults aged ≥60 years with serum α-Klotho data; 493 also had a complete blood count with differential. α-Klotho was analyzed continuously because no universally accepted clinical reference interval or diagnostic cut-point exists. The primary analysis assessed the Spearman correlation between α-Klotho and absolute eosinophil count; eosinophil percentage and the eosinophil-to-lymphocyte ratio were supportive measures. Robust linear regression estimated the percentage difference in α-Klotho per 1-standard-deviation increase in log-eosinophil count after adjustment for demographic, renal, hematological, smoking, and respiratory factors. Results: The median serum α-Klotho concentration was 1354.99 pg/mL (interquartile range 979.54-4047.59), and the median absolute eosinophil count was 0.14 ×10⁹/L (0.09-0.20). α-Klotho correlated positively with absolute eosinophils (Spearman ρ = 0.175; false-discovery-rate-adjusted q = 0.001), eosinophil percentage (ρ = 0.152; q = 0.004), and the eosinophil-to-lymphocyte ratio (ρ = 0.139; q = 0.008). In the fully adjusted model (n = 479), each 1-standard-deviation increase in log-eosinophils was associated with 22.3% higher α-Klotho (95% confidence interval 9.1-37.0%; p < 0.001). The association persisted after restricting α-Klotho to its 1st-99th percentiles (16.9% higher; 95% confidence interval 4.6-30.7%; p = 0.006) and after adjustment for study centre. Conclusion: Higher circulating α-Klotho was independently associated with higher absolute and relative eosinophil measures in this older Central Asian cohort. The direction differs from some population-based reports and should be considered hypothesis-generating. Prospective studies with eosinophil phenotyping, allergy and parasite assessment, and standardized α-Klotho assays are needed before the finding can be interpreted in relation to healthy longevity.