William E. Holmes

Mr. William E. Holmes


Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 August 2022 in Environmental Research
Verified
Journal Article
Closed access
XZXu Zhang
Xu Zhang
DGDaniel Dianchen Gang
Daniel Dianchen Gang
XLXiaobo Lei
Xiaobo Lei
TWTiejun Wang
Tiejun Wang
QLQiyu Lian
Qiyu Lian
HYHong Yao
Hong Yao

21 December 2020 in Applied Sciences
Verified
Journal Article
Open access
PDF file
BSBimi Shrestha
Bimi Shrestha
RHRafael Hernandez
Rafael Hernandez
Dhan Lord FortelaDhan Lord Fortela
Dhan Lord Fortela
WSWayne Sharp
Wayne Sharp
ACAndrei Chistoserdov
Andrei Chistoserdov
MZMark Zappi
Mark Zappi
The rapid increase in the population is expected to result in the approaching of design capacity for many US wastewater treatment plants (WWTPs) over the next decade. WWTPs treat both municipal and industrial wastewater influents, resulting in the production of biosolids after digestion. Biogas, a potential recovered alternative energy source, is also produced as an output from successful anaerobic digestion. More than 7M of dry tons/year of biosolids produced in the US are most often disposed in either landfills or land-applied (~80%). These options are becoming more challenging to implement due to increases in transportation costs and tipping fees, decreases in the availability of landfill/landfarm space, and most importantly, increased regulations. This situation is strongly encouraging WWTPs to find alternatives for the disposal of biosolids. Developing alternative management/disposal options for biosolids are evolving. One of the most attractive alternative option from a sustainability perspective are biorefineries (converts waste to commercial products), which are a fast-growing option given the push toward circular urban source economies (little to no waste generation). Anaerobic digestion has been widely applied in WWTPs to reduce the volume of activated sludge due to its low energy requirements, effective handling of fluctuations due to organic loading rate, relative flexibility with temperature and pH changes, and since biogas is produced that can be transformed into energy. Various pretreatment methods for waste sludges prior to digestion that have been studied to reduce solids production and increase the energetic content of the biogas are presented and discussed. Solids handling and management, which comprises ~60% of the operational cost of a WWTP, is estimated to save more than $100 M annually by achieving at least 20% reduction in the annual production of biosolids within the US. This review incorporates an assessment of various pretreatment methods to optimize the anaerobic digestion of waste sludges with a focus on maximizing both biosolids reduction and biogas quality.

1 October 2021 in Chemosphere
Verified
Journal Article
Closed access
QLQiyu Lian
Qiyu Lian
FIFahrin Islam
Fahrin Islam
ZAZaki Uddin Ahmad
Zaki Uddin Ahmad
XLXiaobo Lei
Xiaobo Lei
Dilip DepanDilip Depan
Dilip Depan
HYHui Yan
Hui Yan

11 May 2023 in Gas Science and Engineering
Verified
Journal Article
Closed access
PCPercival Soni Castro
Percival Soni Castro
GZGerson Martinez Zuniga
Gerson Martinez Zuniga
WHWilliam E. Holmes
William E. Holmes
PBPrashanth Buchireddy
Prashanth Buchireddy
DGDaniel Gang
Daniel Gang
RHRafael Hernandez
Rafael Hernandez

10 November 2023 in BioTechniques
Verified
Journal Article
Open access
Dhan Lord FortelaDhan Lord Fortela
Dhan Lord Fortela
AMAshley P Mikolajczyk
Ashley P Mikolajczyk
MCMiranda R Carnes
Miranda R Carnes
WSWayne Sharp
Wayne Sharp
EREmmanuel Revellame
Emmanuel Revellame
MZMark Zappi
Mark Zappi
This study computationally evaluates the molecular docking affinity of various perfluoroalkyl and polyfluoroalkyl substances (PFAs) towards blood proteins using a generative machine-learning algori... Tweetable abstract This study demonstrates the capability of generative AI algorithm DiffDock to accelerate protein PFA molecular docking computations that can lead to efficient studies of PFA fate... Graphical abstract

21 February 2023 in Acta Astronautica
Verified
Journal Article
Closed access
RARemil Aguda
Remil Aguda
CSCody Stelly
Cody Stelly
LFLucile Fonseca
Lucile Fonseca
SLShayla LeBoeuf
Shayla LeBoeuf
SMShahrzad Massiha
Shahrzad Massiha
EREmmanuel Revellame
Emmanuel Revellame