Relevance.Nutrition is the most important biological factor on which the functioning of the human body depends. The link between the development of colorectal cancer and nutrition and eating habits is well known: excessive consumption of red meat, fats, alcohol, lack of dietary fiber, obesity. Objective: To assess the prevalence and significance of factors related to nutrition and food habits in the development of colorectal cancer (CRC) in the population of the Omsk region.Materials and methods.An epidemiological analytical study (case-control) was conducted, in which 609 people took part - residents of the Omsk Region aged 30 to 85 years (average age 51.2 years; 95% CI 48.1 – 54.3). The study examined 23 factors characterizing the diet and eating habits of study participants.Result and discussion.Of the 23 risk factors for CRC associated with nutrition and food habits, only six confirmed their importance to the residents of the Omsk region: a body mass index of more than 25, alcohol consumption more than twice a month with a predominance of strong, the frequency of red meat consumed more than 10 times a month, the amount of fresh fruit consumed is less than 100 grams at a time, the preference for fatty foods.Findings.The implementation of preventive measures, taking into account the prevalence of risk factors for CRC, including factors related to nutrition and eating habits, reduces the population and individual risk of this pathology in the population of the region, as well as health losses due to malignant neoplasms of the colon and colon.

The study objective is to compare the level of micronutrients in men with infertility and men with normal fertility. Materials and methods. The levels of А, В ₉ , D, Е, С vitamins in blood using high-performance liquid chromatography and selenium and zinc in hair using atomic absorption mass-spectrometry were measured in men with diagnosis of male idiopathic infertility (n = 82) and men with normal fertility (n = 93). Conclusion. Absence of a total lack of micronutrient deficiency in men with infertility was observed. Presumably, azoospermia can be associated with deficiency in some micronutrients casting doubt on the necessity of administration of multicomponent vitamin and mineral complexes. Results. Blood levels of А, D and В ₉ vitamins did not significantly differ in the studied groups, while differences in blood levels of С and Е vitamins and selenium and zinc in hair were statistically significant. While the levels of А, Е, В ₉ vitamins, selenium and zinc were in the reference ranges, vitamin C deficiency was observed in the test group and vitamin D deficiency in both groups. Higher level of selenium in the test group presumably reflects its higher metabolism due to higher influx of xenobiotics in the organism and indicates pre-deficiency state.