Thummala Chandrasekhar

Dr. Thummala Chandrasekhar


Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Lebaka Veeranjaneya ReddyLebaka Veeranjaneya Reddy
Lebaka Veeranjaneya Reddy
YWYoung-Jung Wee
Young-Jung Wee
Weibing YeWeibing Ye
Weibing Ye
MALLIKARJUNA KORIVIMALLIKARJUNA KORIVI
MALLIKARJUNA KORIVI
Mango (Mangifera indica L.), known as the king of fruits, has an attractive taste and fragrance and high nutritional value. Mango is commercially important in India, where ~55% of the global crop is produced. The fruit has three main parts: pulp, peel, and kernel. The pulp is the most-consumed part, while the peel and kernel are usually discarded. Mango pulp is a source of a variety of reducing sugars, amino acids, aromatic compounds, and functional compounds, such as pectin, vitamins, anthocyanins, and polyphenols. Mango processing generates peels and kernels as bio-wastes, though they also have nutraceutical significance. Functional compounds in the peel, including protocatechuic acids, mangiferin and β-carotene are known for their antimicrobial, anti-diabetic, anti-inflammatory, and anti-carcinogenic properties. The mango kernel has higher antioxidant and polyphenolic contents than the pulp and peel and is used for oil extraction; it’s possible usage in combination with corn and wheat flour in preparing nutraceuticals is being increasingly emphasized. This review aims to provide nutraceutical and pharmacological information on all three parts of mango to help understand the defense mechanisms of its functional constituents, and the appropriate use of mangoes to enhance our nutrition and health.

1 May 2008 in Bioresource Technology
Verified
Journal Article
Closed access
Lebaka Veeranjaneya ReddyLebaka Veeranjaneya Reddy
Lebaka Veeranjaneya Reddy
YWYoung-Jung Wee
Young-Jung Wee
JYJong-Sun Yun
Jong-Sun Yun
HRHwa-Won Ryu
Hwa-Won Ryu

6 January 2020 in Biomolecules
Verified
Journal Article
Open access
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SSSaiganesh Srihasam
Saiganesh Srihasam
TKThyagarajan Krishnan
Thyagarajan Krishnan
MALLIKARJUNA KORIVIMALLIKARJUNA KORIVI
MALLIKARJUNA KORIVI
Lebaka Veeranjaneya ReddyLebaka Veeranjaneya Reddy
Lebaka Veeranjaneya Reddy
M. Siva Pratap ReddyM. Siva Pratap Reddy
M. Siva Pratap Reddy
In the present study, economically viable NiO nanoparticles were produced by biogenic preparation using stevia leaf broth and their in-vitro antioxidant and antimicrobial activities were evaluated. The properties of the prepared NiO nanoparticles were confirmed by analytical techniques such as Ultraviolet-Visible (UV-Vis), X-ray diffraction (XRD), FE-SEM, and Fourier transform infrared spectroscopy (FTIR) analyses. Morphological studies using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) showed that the size of synthesized nanoparticles ranged from 20 to 50 nm, most of which were spherical and few of which were agglomerated. The role of the biological moieties, which reduce and cap the nanoparticles, was studied using FTIR analysis. The prepared nanoparticles strongly inhibited gram-negative bacteria, which is a camper with gram-positive bacteria and fungi. Furthermore, it performs an effective in-vitro activity through α,α-diphenyl-β-picrylhydrazyl (DPPH) reduction. Thus, it can be concluded that the effective and easy green synthesis process used for NiO nanoparticles provides potential antimicrobial agents against multidrug-resistant microbes.

17 May 2025 in Nanomaterials
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Journal Article
Open access
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Lebaka Veeranjaneya ReddyLebaka Veeranjaneya Reddy
Lebaka Veeranjaneya Reddy
PRPERUGU Ravi
PERUGU Ravi
MRMadhava C Reddy
Madhava C Reddy
TCThummala Chandrasekhar
Thummala Chandrasekhar
Tapas MandalTapas Mandal
Tapas Mandal
Zinc oxide nanoparticles (ZnO NPs) have garnered significant attention across various scientific and technological domains due to their unique physicochemical properties, including high surface area, photostability, biocompatibility, and potent antimicrobial activity. These attributes make ZnO NPs highly versatile, enabling their application in biomedicine, environmental science, industry, and agriculture. They serve as effective antimicrobial agents in medical treatments and as catalysts in environmental purification processes, owing to their ability to generate reactive oxygen species (ROS) and exhibit photocatalytic activity under UV light. Moreover, ZnO NPs are being increasingly employed in advanced drug delivery systems and cancer therapies, highlighting their potential in modern medicine. Their growing popularity is further supported by their ease of synthesis, cost-effectiveness, and capacity for diverse functionalization, which expand their utility across multiple sectors. This review focuses on research from the past five years (2020–2025) on the practical uses of ZnO nanoparticles in the biomedical, environmental, industrial, and agricultural fields. It also highlights current trends, existing challenges, and future perspectives. By examining these aspects, the article provides a comprehensive understanding of the versatile roles of ZnO NPs and their emerging significance in science and technology.

6 November 2022 in Fermentation
Verified
Journal Article
Open access
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JKJua Kim
Jua Kim
Young-Min KimYoung-Min Kim
Young-Min Kim
Lebaka Veeranjaneya ReddyLebaka Veeranjaneya Reddy
Lebaka Veeranjaneya Reddy
YWYoung-Jung Wee
Young-Jung Wee
Lactic acid, an organic acid produced by numerous microorganisms, has many applications in the food, chemical, pharmaceutical, and polymer industries, with novel applications being developed particularly in the chemical industry. The lactic acid market has steadily grown with the introduction of novel and environmentally friendly products. Therefore, developing novel technologies for lactic acid production, with improved yield and reduced production costs, has become a major research goal. Utilization of inexpensive and renewable biomass is a major strategy for economically producing lactic acid. However, most lactic acid bacteria cannot directly utilize lignocellulosic biomass and require hydrolysis, which is costly. Immobilization techniques for large-scale production can enhance fermentation yield. Moreover, novel techniques, such as cell recycling systems and simultaneous saccharification, will enable microorganisms to produce lactic acid with increased concentration, yield, and productivity. Recently, genetic and metabolic engineering methods have been used for key solving problems, such as product inhibition, by-product formation, and suboptimal culture conditions, and for the effective use of cheap substrates. This review presents comprehensive insights into the most recent advances in the biological production of lactic acid from different substrates, bioprocess techniques for yield improvement, lactic acid purification, and applications of lactic acid for human welfare.

1 December 2005 in World Journal of Microbiology and Biotechnology
Verified
Journal Article
Closed access
PDF file
Lebaka Veeranjaneya ReddyLebaka Veeranjaneya Reddy
Lebaka Veeranjaneya Reddy
ORO. V. S. Reddy
O. V. S. Reddy