The dynamic spheroidization mechanism and its orientation dependence in Ti-6Al-2Mo-2V-1Fe alloys during subtransus hot deformation were studied in this work. For this purpose, hot compression tests were carried out at temperatures of 780–880 °C, with strain rates of 0.001–0.1 s⁻¹. Based on SEM, EBSD and TEM characterization, the results showed that the aspect ratio of the α phase decreased with increasing deformation temperatures and decreasing strain rates. At 880 °C/0.001 s⁻¹, the aspect ratio of the α phase was the smallest at 2.05. The proportion of HAGBs decreased with increasing temperatures and strain rates, which was different from the trend of the spheroidization; this indicated that the formation of HAGBs was not necessary for the spheroidization process. Furthermore, the formation of the α/α interface was related to the evolution of dislocations and twin boundaries at high (880 °C) and low temperatures (780 °C), respectively. Moreover, the dependence of lamellar spheroidization on the crystallographic orientation tilt from the compression direction (θ) was clarified: when θ was between 45° and 60°, both the prism slip and basal slip systems were activated together, which was more favorable for spheroidization. This study could provide guidance for titanium alloy process designs and microstructure regulation.

The β grain size in titanium alloys during industrial forging is critical for balancing toughness, cost-effectiveness, and processability. To address the industrial challenge of high cost and difficulty in refining β grains to the tens of micrometers scale, this study investigates the feasibility of achieving a superior strength–ductility balance in TC18 alloy with near-industrial coarse β grains (296~857 μm) under room temperature tension. A pronounced inverse correlation is observed between β grain size and both strength and ductility. The yield strength–grain size relationship follows the Hall–Petch effect, while the anomalous increase in ductility for fine-grained specimens is attributed to three factors. First, smaller grains provide a higher grain boundary density, promoting stress redistribution and mitigating stress concentrations. Second, more uniform stress distribution induces thinner, denser kink bands that enhance plasticity. Third, strain-induced martensite evolves from discrete nanoscale particles to discontinuous lines and ultimately coalesces into continuous planar bands along the (112)β and (110)β planes. This phase transformation, which initiates below a critical grain size of ~500 μm, further alleviates stress concentrations towards slip bands and contributes to dynamic work hardening. The findings demonstrate that coordinated deformation mechanisms enable excellent mechanical performance even in coarse-grained microstructures, providing a practical pathway for optimizing industrial-grade titanium alloys.