For the purpose of studying compact strip production (CSP) funnel-shaped mold and flexible thin-slab rolling (FTSR) funnel-shaped mold, a three-dimensional (3D) multi-field coupling mathematical model was established to describe the electromagnetic braking (EMBr) continuous casting process. To investigate the metallurgical effect of EMBr in the CSP and FTSR funnel-shaped thin-slab molds, a Reynolds-averaged Navier–Stokes (RANS) turbulence model, together with an enthalpy–porosity approach, was established to numerically simulate the effect of ruler EMBr on the behaviors of melt flow, heat transfer, solidification, and inclusion movement in high-speed casting. The simulation results indicate that the application of ruler EMBr in the CSP and FTSR molds shows great potential to improve the surface temperature of molten steel and reduce the penetration depth of downward backflow. This contributes to the melting of the slag rim near the meniscus region and facilitates the floating removal of the inclusions in the molten pool. In addition, in comparison with the case of no EMBr, the parametric study shows that the braking effect of ruler EMBr with an electromagnetic parameter of 0.5 T can enhance the upward backflow in the two high-speed thin-slab molds. The enhanced upward backflow can successfully entrain the inclusions to the top of the mold and improve the activity of surface fluctuations to avoid the formation of the slag rim. For instance, for the ruler EMBr applied to the FTSR mold, the maximum amplitude of surface fluctuation and the floatation removal quantity of inclusions with a diameter of 100 μm are increased by 4.6 percent and 51 percent, respectively.

A fast and low-cost method for HBV genotyping especially for genotypes A, B, C and D was developed and tested. A classifier was used to detect and analyze a one-step immunoassay lateral flow strip functionalized with genotype-specific monoclonal antibodies (mAbs) on multiple capture lines in the form of pattern recognition for point-of-care (POC) diagnostics. The fluorescent signals from the capture lines and the background of the strip were collected via multiple optical channels in parallel. A digital HBV genotyping model, whose inputs are the fluorescent signals and outputs are a group of genotype-specific digital binary codes (0/1), was developed based on the HBV genotyping strategy. Meanwhile, a companion decoding table was established to cover all possible pairing cases between the states of a group of genotype-specific digital binary codes and the HBV genotyping results. A logical analyzing module was constructed to process the detected signals in parallel without program control and its outputs were used to drive a set of LED indicators, which determine the HBV genotype. Comparing to the nucleic acid analysis to HBV viruses, much faster HBV genotyping with significantly lower cost can be obtained with the developed method.