Agri-food systems are increasingly exposed to environmental, economic, and social challenges, including climate change, biodiversity loss, resource depletion, and growing territorial inequalities. In this context, agroecology is increasingly recognised as a transformative paradigm integrating ecological, economic, social, cultural, and political dimensions within broader processes of food-system transition. Within the PRIMA AgrEcoMed project, 24 Italian agroecological initiatives led by women and young farmers were analysed to explore their contribution to agroecological transition processes in Mediterranean rural areas. The study adopts a qualitative multiple-case study approach and evaluates the selected initiatives through the framework of the 13 Principles of Agroecology proposed by the High-Level Panel of Experts on Food Security and Nutrition, organised into three operational axes: improving resource efficiency, strengthening resilience, and ensuring social responsibility and fairness. The results show that the analysed initiatives combine ecological farming practices with processes of multifunctionality, territorial networking, knowledge co-creation, short supply chains, and community engagement. The findings suggest that several initiatives move beyond input-reduction strategies associated with “weak agroecology” and display characteristics consistent with stronger agroecological pathways based on territorial embeddedness, collective learning, and the reorganisation of relationships between production, consumption, and local communities. The paper highlights the relevance of agroecology not only as an environmentally sustainable farming approach, but also as a broader socio-ecological and territorial transition process, as well as the importance of policy frameworks to support territorial agroecological systems.

The environmental and social crises affecting global agri-food systems highlight the need for a profound transformation of production models and their territorial relations. In this context, agroecology, understood as science, practice, and movement, has emerged as a paradigm capable of integrating ecological sustainability, social equity, and community participation. Within this framework, the work carried out by CREA in the AgrEcoMed project (new agroecological approach for soil fertility and biodiversity restoration to improve economic and social resilience of Mediterranean farming systems), funded by the PRIMA programme, investigates agroecology as a social and political process of territorial regeneration. This process is grounded in co-design with local stakeholders, collective learning, and the construction of multi-actor networks for agroecology in the Mediterranean. The Manifesto functions as a tool for participatory governance and value convergence, aiming to consolidate a shared vision for the Mediterranean agroecological transition. The article examines, through an analysis of the existing literature, the role of agroecological networks and empirically examines the function of the collective co-creation of the Manifesto as a tool for social innovation. The methodology is based on a participatory action-research approach that used local focus groups, World Café, and thematic analysis to identify the needs of the companies involved. The results highlight the formation of a multi-actor network currently comprising around 90 members and confirm the effectiveness of the Manifesto as a boundary object for horizontal governance. This demonstrates how sustainability can emerge from dialogue, cooperation, and the co-production of knowledge among local actors.