Guang-Zhi  Lin Lin

Mr. Guang-Zhi Lin Lin

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 April 2022 in Applied Sciences
Verified
Journal Article
Open access
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SGShih-Sian Guo
Shih-Sian Guo
KLKuo-Hua Lee
Kuo-Hua Lee
LCLiyun Chang
Liyun Chang
TTTseng Tseng
Tseng Tseng
SSSin-Jhe Sie
Sin-Jhe Sie
Tsair-Fwu LEETsair-Fwu LEE
Tsair-Fwu LEE
This study developed an automated temperature measurement and monitoring platform for dairy cattle. The platform used the YOLO V3-tiny (you only look once, YOLO) deep learning algorithm to identify and classify dairy cattle images. The system included a total of three layers of YOLO V3-tiny identification: (1) dairy cow body; (2) individual number (identity, ID); (3) thermal image of eye socket identification. We recorded each cow’s individual number and body temperature data after the three layers of identification, and carried out long-term body temperature tracking. The average prediction score of the recognition rate was 96%, and the accuracy was 90.0%. The thermal image of eye socket recognition rate was >99%. The area under the receiver operating characteristic curves (AUC) index of the prediction model was 0.813 (0.717–0.910). This showed that the model had excellent predictive ability. This system provides a rapid and convenient temperature measurement solution for ranchers. The improvement in dairy cattle image recognition can be optimized by collecting more image data. In the future, this platform is expected to replace the traditional solution of intrusive radio-frequency identification for individual recognition.

31 July 2026 in Life
Verified
Journal Article
Open access
PDF file
Tsair-Fwu LEETsair-Fwu LEE
Tsair-Fwu LEE
GLGuang-Zhi Lin Lin
Guang-Zhi Lin Lin
WYWen-ping Yun
Wen-ping Yun
YLYi-Lun Liao
Yi-Lun Liao
LCLiyun Chang
Liyun Chang
YANG-WEI HSIEHYANG-WEI HSIEH
YANG-WEI HSIEH
Objective: This study aims to develop a preliminary explainable image-based auxiliary assessment framework for radiation pneumonitis (RP) by integrating a generative adversarial network (GAN), Gradient-weighted Class Activation Mapping (Grad-CAM), and ensemble learning to improve image-based classification performance, interpretability, and computational efficiency. Methods: Chest CT images from 46 lung cancer patients who underwent VMAT were retrospectively collected, yielding 542 RP and 1857 non-RP images. Images were preprocessed using Otsu-based segmentation and standardized before being input into the RP-GAN for feature extraction. Grad-CAM was applied to qualitatively visualize attention patterns across convolutional layers and guide feature-layer selection, while PCA reduced the extracted features from 12,288 to 730 dimensions. An ensemble stacking classifier combining RF, SVM, KNN, and XGBoost with logistic regression as a meta-learner was constructed. Model performance was evaluated using AUC, accuracy, PPV, NPV, specificity, recall, and F1-score. Results: Grad-CAM highlighted conv2d_4 and conv2d_5 as the most informative layers. PCA reduced training time from 49 min to 49 s with minimal performance loss. In the internal hold-out test set, the ensemble model achieved the highest point estimates for AUC and accuracy among the evaluated classifiers (AUC = 0.921; accuracy = 87.1%). The model identified RP-positive CT slices and provided qualitative visual cues for suspected RP-related regions. Conclusions: The proposed GAN–Grad-CAM ensemble framework showed promising internal classification performance for post-treatment CT-based RP image assessment with substantially improved computational efficiency. Its qualitative visual outputs may support clinical image review, although further external validation and quantitative localization assessment are required before clinical application as an auxiliary image-review tool.

18 September 2026 in Life
Verified
Journal Article
Open access
PDF file
GLGuang-Zhi Lin Lin
Guang-Zhi Lin Lin
YANG-WEI HSIEHYANG-WEI HSIEH
YANG-WEI HSIEH
CCChihYu Cheng
ChihYu Cheng
CWChen-Cheng Wang
Chen-Cheng Wang
LCLiyun Chang
Liyun Chang
Tsair-Fwu LEETsair-Fwu LEE
Tsair-Fwu LEE
Background: Radiotherapy-related complications can impair long-term outcomes in nasopharyngeal carcinoma (NPC), while high-volume literature screening remains a bottleneck in evidence synthesis. Methods: Four databases were searched through January 2026. After deduplication, 4916 records underwent two-stage manual screening, yielding 38 studies. Three Bidirectional Encoder Representations from Transformers (BERT) models, BERT-base, BioBERT, and PubMedBERT, were fine-tuned using stratified five-fold cross-validation, and screening performance was assessed using the area under the receiver operating characteristic curve (ROC-AUC), the area under the precision-recall curve (PR-AUC), and work saved over sampling (WSS) at the 100% and 85% recall thresholds (WSS@100% and WSS@85%).The clinical evidence was evaluated using the Prediction Model Risk of Bias Assessment Tool (PROBAST) and synthesized narratively according to endpoint, discrimination metric, time horizon, unit of analysis, validation level, and uncertainty reporting. Results: At complete recall, BioBERT and PubMedBERT achieved mean WSS values of 97.8% and 97.5%, respectively, compared with 89.7% for BERT-base. Separately, the clinical evidence review identified 39 discrimination estimates: 33 conventional binary ROC-AUCs, three Harrell’s C-indices, and three time-dependent AUCs. Only two studies contributed external-validation estimates and one contributed a temporal-validation estimate. Sixteen estimates lacked a usable measure of uncertainty, and PROBAST rated all studies as having a high overall risk of bias, driven by the analysis domain. Conclusions: Within the retrieved and manually annotated corpus, biomedical pretrained language models showed the potential to reduce the title-and-abstract screening burden while maintaining complete recall. Independently, the clinical evidence map identified promising discrimination but insufficiently robust and transportable evidence for routine clinical implementation.