This study aimed to evaluate the relationship between the objective severity of dry eye disease subjective symptoms, and corneal sensitivity. The study included 62 eyes from 31 healthy volunteers and 150 eyes from 75 patients diagnosed with dry eye disease . Participants underwent the Schirmer I test, tear break-up time assessment, and corneal staining evaluation using the Oxford Scale. Subjective symptoms were assessed through the Ocular Surface Disease Index questionnaire and a modified Ocular Surface Pain Score questionnaire. Corneal sensitivity was measured in five corneal regions using a Cochet-Bonnet esthesiometer. Dry eye disease severity was graded from 1 to 5 based on the Oxford Scale. Comparative analyses were performed. Schirmer I and tear break-up time values were significantly lower in the DED group, while Ocular Surface Disease Index and Ocular Surface Pain Score were significantly higher (p<0.001 for all). Corneal sensitivity in all quadrants was significantly lower in DED patients (p<0.001 for all). A strong correlation was observed between the Ocular Surface Pain Score and the Ocular Surface Disease Index (r=0.983, p<0.001). Central corneal sensitivity exhibited a moderate positive correlation with Schirmer I and tear break-up time (p<0.001, r=0.583 and 0.657, respectively) and a moderate negative correlation with Ocular Surface Disease Index and Ocular Surface Pain Score (p<0.001, r=0.625 and -0.631, respectively). Disease severity progression was associated with increased Ocular Surface Disease Index and Ocular Surface Pain Score, but no statistically significant difference was found between Grades 3 and 5. Similarly, corneal sensitivity decreased with advancing disease severity, yet no significant difference was observed between Grades 4 and 5. Corneal sensitivity decreases in dry eye disease and is negatively correlated with disease severity. Subjective symptoms increase with disease progression and show a positive correlation with severity. The absence of significant differences between the advanced stages suggests that neuropathic mechanisms and subbasal nerve plexus deterioration play a role in chronic and late-stage dry eye disease.

Background: In this study, we evaluated whether preoperative foveal morphology assessed using optical coherence tomography is associated with postoperative absolute refractive prediction error after uncomplicated cataract surgery. Methods: This retrospective observational study screened 435 patients and included 91 eyes of 91 patients after exclusions. All included patients underwent phacoemulsification with monofocal intraocular lens implantation. Preoperative spectral-domain optical coherence tomography measurements were used to calculate a foveal steepness index (FSI) as the ratio of the mean inner Early Treatment Diabetic Retinopathy Study (ETDRS) ring thickness to minimum foveal thickness, and foveal depth as the difference between these measurements. The primary outcome was SRK/T-derived absolute prediction error (APE) at one month. A supplementary analysis used Barrett Universal II. Associations were examined using Spearman correlation and univariable and multivariable linear regression analyses. A sensitivity analysis was performed after zeroing the cohort mean signed prediction error. Results: The mean age was 68.2 ± 7.8 years. The mean absolute prediction error was 0.48 ± 0.37 D, with a median of 0.50 D (IQR, 0.25–0.75 D). Overall, 70.3% and 95.6% of eyes had errors within 0.50 and 1.00 D, respectively. FSI and foveal depth were significantly associated with APE in univariable analyses (p = 0.028 and p = 0.013, respectively). The adjusted foveal-depth association was not statistically significant in the primary analysis (p = 0.079) but reached significance after zeroing the mean prediction error (p = 0.032). The supplementary Barrett Universal II analysis did not confirm an adjusted association before or after zeroing the mean signed prediction error. Adding foveal depth did not meaningfully improve leave-one-out cross-validated performance. Conclusions: These exploratory findings suggest a possible association between foveal morphology and SRK/T-derived APE in this study population. Reproducibility across IOL calculation formulas and clinical applicability remain uncertain; validation in a larger prospective cohort is needed.

Objective: To evaluate the impact of cataract surgery on sexual quality of life in female patients using the Sexual Quality of Life–Female (SQOL-F) questionnaire. Methods: This prospective observational study included 67 female patients who underwent cataract surgery. Sexual quality of life was assessed preoperatively and again at 3 months postoperatively using the Sexual Quality of Life–Female (SQOL-F) scale. This is a validated 18-item Likert-type instrument that assesses emotional, psychological, and relational aspects of sexual life. Scores were transformed to a 0–100 scale, with higher scores indicating better sexual quality of life. Demographic variables included age, education level, employment status, and economic status. Statistical comparisons between preoperative and postoperative scores were performed. Results: Sixty-seven women participated. Sexual quality-of-life scores improved after cataract surgery. For patients over 60 years, SQOL-F scores rose from 58.7 ± 7.2 to 76.9 ± 11.3 (p < 0.05). Patients under 60 showed no significant improvement. Those with lower education and those with low or high economic status showed significant gains (p < 0.05), whereas university-educated or employed patients did not. These results show that cataract surgery’s impact on sexual quality of life differs by sociodemographic group. Conclusion: Cataract surgery can improve sexual quality of life in women, especially older patients and those with lower socioeconomic status. This suggests cataract surgery offers psychosocial benefits beyond vision improvement. Larger studies are needed to confirm these findings.