Hesham El-Seedi

Dr. Hesham El-Seedi

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, S-106 91 Stockholm, Sweden
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orcid

Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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31 July 2021 in Insects
Verified
Journal Article
Open access
PDF file
SKShaden Khalifa
Shaden Khalifa
EEEsraa Elshafey
Esraa Elshafey
SSSalah Kamal Hassan AL Sharif
Salah Kamal Hassan AL Sharif
AEAida A. Abd El-Wahed
Aida A. Abd El-Wahed
AAAhmed F. Algethami
Ahmed F. Algethami
Hesham El-SeediHesham El-Seedi
Hesham El-Seedi
Pollination plays a significant role in the agriculture sector and serves as a basic pillar for crop production. Plants depend on vectors to move pollen, which can include water, wind, and animal pollinators like bats, moths, hoverflies, birds, bees, butterflies, wasps, thrips, and beetles. Cultivated plants are typically pollinated by animals. Animal-based pollination contributes to 30% of global food production, and bee-pollinated crops contribute to approximately one-third of the total human dietary supply. Bees are considered significant pollinators due to their effectiveness and wide availability. Bee pollination provides excellent value to crop quality and quantity, improving global economic and dietary outcomes. This review highlights the role played by bee pollination, which influences the economy, and enlists the different types of bees and other insects associated with pollination.

23 August 2019 in Marine Drugs
Verified
Journal Article
Open access
PDF file
SKShaden Khalifa
Shaden Khalifa
Nizar EliasNizar Elias
Nizar Elias
MFMohamed A. Farag
Mohamed A. Farag
LCLei Chen
Lei Chen
ASAamer Saeed
Aamer Saeed
Hesham El-SeediHesham El-Seedi
Hesham El-Seedi
Cancer remains one of the most lethal diseases worldwide. There is an urgent need for new drugs with novel modes of action and thus considerable research has been conducted for new anticancer drugs from natural sources, especially plants, microbes and marine organisms. Marine populations represent reservoirs of novel bioactive metabolites with diverse groups of chemical structures. This review highlights the impact of marine organisms, with particular emphasis on marine plants, algae, bacteria, actinomycetes, fungi, sponges and soft corals. Anti-cancer effects of marine natural products in in vitro and in vivo studies were first introduced; their activity in the prevention of tumor formation and the related compound-induced apoptosis and cytotoxicities were tackled. The possible molecular mechanisms behind the biological effects are also presented. The review highlights the diversity of marine organisms, novel chemical structures, and chemical property space. Finally, therapeutic strategies and the present use of marine-derived components, its future direction and limitations are discussed.

8 August 2019 in RSC Advances
Verified
Journal Article
Open access
PDF file
Hesham El-SeediHesham El-Seedi
Hesham El-Seedi
RERehan M. El-Shabasy
Rehan M. El-Shabasy
SKShaden A. M. Khalifa
Shaden A. M. Khalifa
ASAamer Saeed
Aamer Saeed
ASAfzal Shah
Afzal Shah
WGWeisheng Guo
Weisheng Guo
Nanoparticles (NPs) are new inspiring clinical targets that have emerged from persistent efforts with unique properties and diverse applications.

30 October 2012 in Journal of Agricultural and Food Chemistry
Verified
Journal Article
Closed access
Hesham El-SeediHesham El-Seedi
Hesham El-Seedi
AEAsmaa M. A. El-Said
Asmaa M. A. El-Said
SKShaden A. M. Khalifa
Shaden A. M. Khalifa
UGUlf Göransson
Ulf Göransson
LBLars Bohlin
Lars Bohlin
Robert VerpoorteRobert Verpoorte
Robert Verpoorte

8 February 2022 in Microorganisms
Verified
Journal Article
Open access
PDF file
Awad A ShehataAwad A Shehata
Awad A Shehata
SYSakine Yalçın
Sakine Yalçın
JLJuan Latorre
Juan Latorre
SBShereen Basiouni
Shereen Basiouni
YAYoussef A Attia
Youssef A Attia
Guillermo TellezGuillermo Tellez
Guillermo Tellez
The gut microbiota has been designated as a hidden metabolic ‘organ’ because of its enormous impact on host metabolism, physiology, nutrition, and immune function. The connection between the intestinal microbiota and their respective host animals is dynamic and, in general, mutually beneficial. This complicated interaction is seen as a determinant of health and disease; thus, intestinal dysbiosis is linked with several metabolic diseases. Therefore, tractable strategies targeting the regulation of intestinal microbiota can control several diseases that are closely related to inflammatory and metabolic disorders. As a result, animal health and performance are improved. One of these strategies is related to dietary supplementation with prebiotics, probiotics, and phytogenic substances. These supplements exert their effects indirectly through manipulation of gut microbiota quality and improvement in intestinal epithelial barrier. Several phytogenic substances, such as berberine, resveratrol, curcumin, carvacrol, thymol, isoflavones and hydrolyzed fibers, have been identified as potential supplements that may also act as welcome means to reduce the usage of antibiotics in feedstock, including poultry farming, through manipulation of the gut microbiome. In addition, these compounds may improve the integrity of tight junctions by controlling tight junction-related proteins and inflammatory signaling pathways in the host animals. In this review, we discuss the role of probiotics, prebiotics, and phytogenic substances in optimizing gut function in poultry.

28 January 2020 in Nutrients
Verified
Journal Article
Open access
PDF file
Mohamed FaragMohamed Farag
Mohamed Farag
SJSuzan A. Jomaa
Suzan A. Jomaa
AEAida A. Abd El-Wahed
Aida A. Abd El-Wahed
Hesham El-SeediHesham El-Seedi
Hesham El-Seedi
Kefir is a dairy product that can be prepared from different milk types, such as goat, buffalo, sheep, camel, or cow via microbial fermentation (inoculating milk with kefir grains). As such, kefir contains various bacteria and yeasts which influence its chemical and sensory characteristics. A mixture of two kinds of milk promotes kefir sensory and rheological properties aside from improving its nutritional value. Additives such as inulin can also enrich kefir’s health qualities and organoleptic characters. Several metabolic products are generated during kefir production and account for its distinct flavour and aroma: Lactic acid, ethanol, carbon dioxide, and aroma compounds such as acetoin and acetaldehyde. During the storage process, microbiological, physicochemical, and sensory characteristics of kefir can further undergo changes, some of which improve its shelf life. Kefir exhibits many health benefits owing to its antimicrobial, anticancer, gastrointestinal tract effects, gut microbiota modulation and anti-diabetic effects. The current review presents the state of the art relating to the role of probiotics, prebiotics, additives, and different manufacturing practices in the context of kefir’s physicochemical, sensory, and chemical properties. A review of kefir’s many nutritional and health benefits, underlying chemistry and limitations for usage is presented.