Abarema cochliacarpos é uma espécie endêmica do Brasil, pertence à família Fabaceae e é conhecida popularmente como barbatimão, estando presente na caatinga e cerrado brasileiro. Em Sergipe, seu uso é em forma de chás para atividades anti-inflamatória e cicatrizante. Como objetos deste estudo foram utilizados as folhas do vegetal a fim de conhecer qualitativamente os constituintes químicos das frações obtidas a partir do extrato bruto: fração clorofórmica (FCL), fração hexânica (FHX), fração acetato de etila (FAE) e fração hidrometanólica (FHM) através da prospecção fitoquímica por ensaios colorimétricos, sendo detectada a presença de metabólitos secundários como fenóis, taninos, flavonóis, catequinas, esteroides, triterpenóides e saponinas. Na análise antimicrobiana apenas duas frações apresentaram halos de inibição. A FAE para as cepas de Staphylococcus aureus (19,3 mm), Enterococcus durans hirae (10 mm), Escherichia coli derivada (9,6 mm) e Pseudomonas aeruginosa derivada (15 mm), e a FCL para a cepa E. durans hirae (9 mm). Na concentração inibitória mínima (MIC) a FAE sobressaiu-se com 12,5 µg.mL-1 para a S. aureus e E. durans, enquanto a FCL obteve 25 µg.mL-1 para E. durans. Quanto à análise citotóxica, a FAE nas concentrações testadas não favoreceu a viabilidade celular em 75%, apresentando capacidade antiproliferativa, exceto a FLC a 20 µg.mL-1. A FAE e FCL apresentaram propriedades antioxidantes e obtiveram efeito antimicrobiano, além de possuírem metabólitos que corroboram com essas funções.

Poly(3-hydroxybutyrate) (PHB)-based films containing Poly(ethylene glycol) (PEG), esterified sodium alginate (ALG-e) and polymeric additives loaded with Ag nanoparticles (AgNPs) were obtained by a conventional casting method. AgNPs were produced in aqueous suspension and added to polymeric gels using a phase exchange technique. Composite formation was confirmed by finding the Ag peak in the XRD pattern of PHB. The morphological analysis showed that the inclusion of PEG polymer caused the occurrence of pores over the film surface, which were overshadowed by the addition of ALG-e polymer. The PHB functional groups were dominating the FTIR spectrum, whose bands associated with the crystalline and amorphous regions increased after the addition of PEG and ALG-e polymers. Thermal analysis of the films revealed a decrease in the degradation temperature of PHB containing PEG/AgNPs and PEG/ALG-e/AgNPs, suggesting a catalytic effect. The PHB/PEG/ALG-e/AgNPs film combined the best properties of water vapor permeability and hydrophilicity of the different polymers used. All samples showed good antimicrobial activity in vitro, with the greater inhibitory halo observed for the PEG/PEG/AgNPs against Gram positive S. aureus microorganisms. Thus, the PHB/PEG/ALG-e/AgNPs composite demonstrated here is a promising candidate for skin wound healing treatment.

Genipa americana L. is a plant native to the Americas, popularly known in Brazil as Jenipapeiro, and is chemically characterized by the presence of genipin, which has pharmacological actions such as anti-inflammatory and antioxidant. The bark is used for its antiulcerogenic and antidiarrheal activities. Research developed for chemical knowledge have shown the plant is of interest for the production of efficient drugs such as antioxidants and antimicrobials. Free-living parasites, including those of the genus Acanthamoeba, have aroused interest and the study of plants used in folk medicine is a strategy for the discovery of conventional treatments to the infections caused by this parasite to be used pure or in preparations such as microemulsions (ME), which offer advantages related to the release of drugs and the absorption of the active ingredient. The aim of the study was to evaluate antiparasitic and antioxidant activities as well as to obtain a ME from the hydroethanolic extract (HEE) of G. americana. The DPPH free radical reduction method was used to evaluate the antioxidant activity of HEE, which showed an inhibition percentage (PI) of 47.82%. The antiparasitic activity of the HEE using A. castellanii trophozoites showed a PI of 80% at the highest concentration tested (9 mg mL^-1). The ME containing 10% HEE was characterized for its droplet size (18.33 µm), pH (5.68) and polydispersity index (0.19). Therefore, the HEE presented antioxidant and antiparasitic effects, while its microemulsion showed potential to disperse particles.

This study performs a computationally reproducible multicriteria reanalysis of a four-criterion, UASB-oriented source matrix reported in a 2015 MSc dissertation. Two author-generated numerical scenarios, each containing six WWTP alternatives, are treated as constructed cases rather than verified operating-plant data. The retained criteria are UASB presence, a source-defined flow variable with an unresolved physical unit, CH₄ concentration, and H₂S concentration. Source-rule coding was rechecked, continuous values were ranked with TOPSIS and a weighted sum model (WSM), and sensitivity was examined through threshold perturbation, criterion-weight variation, and an explicit flow-variable test. Four coding inconsistencies were corrected. Under equal weights, WWTP6 ranked first in Case 1 and WWTP1 in Case 2, with 93.3% TOPSIS–WSM pairwise agreement in both cases. Multiplying or dividing the complete flow column by 24 left TOPSIS and WSM scores and ranks unchanged to numerical precision; removing flow preserved the first-ranked alternative in both scenarios but changed some intermediate positions. The results characterize only the documented four-criterion, UASB-oriented matrix and do not estimate absolute gas production, energy output, or economic feasibility.

Anais do Congresso Internacional de Engenharia Mecânica e Industrial (2764-4294) - Membranas De Alginato De Sódio E Fibroína De Seda Dopadas Com Nanopartículas De Prata: Preparação E Caracterização