Christoph Ostgathe

Christoph Ostgathe

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Research Focus & Metrics

Academic Career Length

26Years (2001-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2008 in Palliative Medicine
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Journal Article
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TPT Pastrana
T Pastrana
SJS Jünger
S Jünger
COChristoph Ostgathe
Christoph Ostgathe
FEF Elsner
F Elsner
LRL Radbruch
L Radbruch
For more than 30 years, the term “palliative care” has been used. From the outset, the term has undergone a series of transformations in its definitions and consequently in its tasks and goals. There remains a lack of consensus on a definition. The aim of this article is to analyse the definitions of palliative care in the specialist literature and to identify the key elements of palliative care using discourse analysis: a qualitative methodology. The literature search focused on definitions of the term ‘palliative medicine’ and ‘palliative care’ in the World Wide Web and medical reference books in English and German. A total of 37 English and 26 German definitions were identified and analysed. Our study confirmed the lack of a consistent meaning concerning the investigated terms, reflecting on-going discussion about the nature of the field among palliative care practitioners. Several common key elements were identified. Four main categories emerged from the discourse analysis of the definition of palliative care: target groups, structure, tasks and expertise. In addition, the theoretical principles and goals of palliative care were discussed and found to be key elements, with relief and prevention of suffering and improvement of quality of life as main goals. The identified key elements can contribute to the definition of the concept ‘palliative care’. Our study confirms the importance of semantic and ethical influences on palliative care that should be considered in future research on semantics in different languages.

26 July 2018 in Scientific Reports
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Journal Article
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Christoph WillChristoph Will
Christoph Will
KSKilin Shi
Kilin Shi
SSSven Schellenberger
Sven Schellenberger
TSTobias Steigleder
Tobias Steigleder
FMFabian Michler
Fabian Michler
AKAlexander Kölpin
Alexander Kölpin
This paper introduces heart sound detection by radar systems, which enables touch-free and continuous monitoring of heart sounds. The proposed measurement principle entails two enhancements in modern vital sign monitoring. First, common touch-based auscultation with a phonocardiograph can be simplified by using biomedical radar systems. Second, detecting heart sounds offers a further feasibility in radar-based heartbeat monitoring. To analyse the performance of the proposed measurement principle, 9930 seconds of eleven persons-under-tests’ vital signs were acquired and stored in a database using multiple, synchronised sensors: a continuous wave radar system, a phonocardiograph (PCG), an electrocardiograph (ECG), and a temperature-based respiration sensor. A hidden semi-Markov model is utilised to detect the heart sounds in the phonocardiograph and radar data and additionally, an advanced template matching (ATM) algorithm is used for state-of-the-art radar-based heartbeat detection. The feasibility of the proposed measurement principle is shown by a morphology analysis between the data acquired by radar and PCG for the dominant heart sounds S1 and S2: The correlation is 82.97 ± 11.15% for 5274 used occurrences of S1 and 80.72 ± 12.16% for 5277 used occurrences of S2. The performance of the proposed detection method is evaluated by comparing the F-scores for radar and PCG-based heart sound detection with ECG as reference: Achieving an F1 value of 92.22 ± 2.07%, the radar system approximates the score of 94.15 ± 1.61% for the PCG. The accuracy regarding the detection timing of heartbeat occurrences is analysed by means of the root-mean-square error: In comparison to the ATM algorithm (144.9 ms) and the PCG-based variant (59.4 ms), the proposed method has the lowest error value (44.2 ms). Based on these results, utilising the detected heart sounds considerably improves radar-based heartbeat monitoring, while the achieved performance is also competitive to phonocardiography.

17 July 2018 in Annals of Oncology
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PLP.J. Larkin
P.J. Larkin
NCN.I. Cherny
N.I. Cherny
DCD. La Carpia
D. La Carpia
MGM. Guglielmo
M. Guglielmo
COChristoph Ostgathe
Christoph Ostgathe
CRC.I. Ripamonti
C.I. Ripamonti
Constipation is a common problem in patients with advanced cancer and a significant source of major morbidity and distress, which is often under-appreciated [1]. Constipation is subjectively experienced by the patient and diagnostic criteria do not always clearly express the diversity of factors, which may lead to constipation as a clinical problem [2]. Widespread use of opioid analgesics for cancer pain poses specific challenges for patients [3]. Despite its clinical impact, constipation is both poorly recognised and poorly treated. Oncologists must be familiar with the common causes of constipation among cancer patients and the strategies to evaluate and manage this distressing symptom. This European Society for Medical Oncology (ESMO) Clinical Practice Guideline (CPG) is directed towards adult cancer patients experiencing constipation as a consequence of their cancer diagnosis or treatment. The CPG makes specific reference to the context of opioid-induced constipation (OIC), highlights the impact of constipation and offers strategies for pharmacological and non-pharmacological management, as well as the specific challenges in the management of older patients with cancer at enhanced risk of constipation.

1 October 2010 in Der Schmerz
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Journal Article
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SSS. Stiel
S. Stiel
MMM.E. Matthes
M.E. Matthes
LBL. Bertram
L. Bertram
COChristoph Ostgathe
Christoph Ostgathe
FEF. Elsner
F. Elsner
LRL. Radbruch
L. Radbruch

11 October 2010 in Palliative Medicine
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Journal Article
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COChristoph Ostgathe
Christoph Ostgathe
BABernd Alt-Epping
Bernd Alt-Epping
HGHeidrun Golla
Heidrun Golla
JGJan Gärtner
Jan Gärtner
GLGabriele Lindena
Gabriele Lindena
THThe Hospice
The Hospice
To determine the role of non-cancer palliative care in inpatient services in Germany, data from the Hospice and Palliative Care Evaluation (HOPE) were analysed. Since 1999, a three-month census has been conducted annually in German palliative care units. Pooled data from 2002–2005 were tested for differences between non-cancer patients (NCs) and cancer patients (Cs). A total of 4182 patients (NC: 3.5%; C: 96.5%) were documented; functional status (using Eastern Cooperative Oncology Group (ECOG) measures) in NCs was lower compared to Cs (p = 0.009). NCs suffered more often from dyspnoea (40%; C: 29%; p = 0.004), weakness (92,3%; C: 84,5%; p = 0.011) and tiredness (75.4%; C: 66.7%; p = 0.03) and less from nausea (17.1%; C: 28.9%; p = 0.002), vomiting (8.2%; C: 19.4%; p = 0.001) or loss of appetite (55.5%; C: 67.9%; p = 0.002). There were no differences in pain and constipation. Other problems (nursing, psychological) were more frequent for NCs, in particular the need for support in the activities of daily life (90.3%; C: 72.8%; p < 0.001) and disorientation/confusion (32.1%; C: 17.2%; p < 0.001). There were no differences in social problems. NCs are still rare in specialized inpatient palliative care institutions in Germany. The palliative care needs in patients with non-malignant disease will challenge the health care system as the workload for these services will grow over proportionally.

1 November 2003 in Supportive Care in Cancer
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Journal Article
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EKE. Klaschik
E. Klaschik
FNF. Nauck
F. Nauck
COChristoph Ostgathe
Christoph Ostgathe