An experimental research study was carried out to analyze the influence of different orifice geometries (conical and cylindrical) on the injection rate behavior of a Common-Rail fuel injection system. For that purpose, injection tests in two different injection test rigs were conducted. This behavior of the injection rate in the different nozzles was characterized by using the non-dimensional parameters of cavitation number (K), discharge coefficient (Cd) and Reynolds number (Re). First, some relevant physical properties of the injected fuel were accurately characterized (density, kinematic viscosity and sound speed in the fluid) in a specific test rig as a function of the operating conditions (pressure and temperature). The behavior of both nozzles was analyzed at maximum injector needle lift under steady flow conditions in a cavitation test rig. Injection pressure and pressure at the nozzle discharge were controlled in order to modify the flow conditions. In addition, the nozzles were characterized in real unsteady flow conditions in an injection-rate test rig. From the raw results, the values of the relevant parameters were computed, and the occurrence of cavitation was clearly identified. The results evidenced interesting differences in the permeability of both nozzle geometries and a clear resistance of the conical nozzle to cavitation.