Miriam Cruz-Leal

Prof. Miriam Cruz-Leal


Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 September 2019 in Nanomaterials
Verified
Journal Article
Open access
PDF file
MCMiriam Cruz-Leal
Miriam Cruz-Leal
OAOscar Goiz Amaro
Oscar Goiz Amaro
FCF. Chávez
F. Chávez
GPG. F. Pérez-Sánchez
G. F. Pérez-Sánchez
NHNorberto Hernandez-Como
Norberto Hernandez-Como
CFCarlos Felipe
Carlos Felipe
High-porosity nanostructured amorphous tungsten OXIDE (a-WO3) films were synthesized by a Hot Filament Chemical Vapor Deposition technique (HFCVD) and then transformed into a crystalline WO3 by simple thermal annealing. The a-WO3 films were annealed at 100, 300, and 500 °C for 10 min in an air environment. The films were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), micro-Raman spectroscopy, high-resolution transmission electron microscopy (HR-TEM), and UV–vis spectroscopy. Results revealed that the a-WO3 films were highly porous, composed of cauliflower-like structures made of nanoparticles with average sizes of 12 nm. It was shown that the effect of annealing on the morphology of the a-WO3 films leads to a sintering process. However, the morphology is conserved. It was found that at annealing temperatures of 100 °C, the a-WO3 films are of an amorphous nature, while at 300 °C, the films crystallize in the monoclinic phase of WO3. The calculated bandgap for the a-WO3 was 3.09 eV, and 2.53 eV for the film annealed at 500 °C. Finally, the results show that porous WO3 films preserve the morphology and maintain the porosity, even after the annealing at 500 °C.

29 November 2025 in Textiles
Verified
Journal Article
Open access
PDF file
JTJosé Ángel Juárez Torres
José Ángel Juárez Torres
MCMaría Luisa Castellanos Cabrera
María Luisa Castellanos Cabrera
DMDalia Molina-Romero
Dalia Molina-Romero
IAItzel Pamela Torres Avila
Itzel Pamela Torres Avila
OAOscar Goiz Amaro
Oscar Goiz Amaro
MCMiriam Cruz-Leal
Miriam Cruz-Leal
This study presents the development and application of a textile finishing treatment with antimicrobial properties based on silver nanostructures. The methodology involved the initial synthesis of silver-supported structures on aluminosilicates, which were subsequently applied to 100% raw cotton Jersey fabric through an impregnation finishing process. The treated cotton samples were evaluated for antimicrobial activity using the Kirby-Bauer disk diffusion method. The tested bacterial strains included Gram-negative as Shigella sp., Pseudomonas sp. M13, Pseudomonas sp. M14, Pseudomonas putida KT2440, and Escherichia coli, as well as Gram-positive Staphylococcus aureus ATCC 29213 and Streptococcus agalactiae ATCC 12386 (American Type Culture Collection) all of which exhibited growth inhibition in the presence of the treated textile, demonstrating the effectiveness of the antimicrobial finish.

12 December 2023 in MRS Advances
Verified
Journal Article
Closed access
PDF file
MCMiriam Cruz-Leal
Miriam Cruz-Leal
OGO. Goiz
O. Goiz
TNTania I. Márquez Niño
Tania I. Márquez Niño
ECE. Coutino-Gonzalez
E. Coutino-Gonzalez
AAAlondra Albarado-Ibañez
Alondra Albarado-Ibañez
JCJ. A. Alcantara C.
J. A. Alcantara C.

27 October 2026 in Results in Surfaces and Interfaces
Verified
Journal Article
Open access
JCJosé Luis Castrejón-Flores
José Luis Castrejón-Flores
ÁCÁngel Daniel Campos-Juárez
Ángel Daniel Campos-Juárez
AUAlexis Chino Ulloa
Alexis Chino Ulloa
ARAbraham Josue Nevarez Ramirez
Abraham Josue Nevarez Ramirez
MCMiriam Cruz-Leal
Miriam Cruz-Leal
IAItzel Pamela Torres Avila
Itzel Pamela Torres Avila

12 August 2026 in SSRN Electronic Journal
Verified
Preprint
Open access
JCJosé Luis Castrejón-Flores
José Luis Castrejón-Flores
ÁCÁngel Daniel Campos-Juárez
Ángel Daniel Campos-Juárez
Alexis Chino-UlloaAlexis Chino-Ulloa
Alexis Chino-Ulloa
ARAbraham Josue Nevarez Ramirez
Abraham Josue Nevarez Ramirez
MCMiriam Cruz-Leal
Miriam Cruz-Leal
IAItzel Pamela Torres Avila
Itzel Pamela Torres Avila
Despite the favorable mechanical properties and biocompatibility of Ti-6Al-4V, surface modification remains essential to enhance osseointegration and ensure long-term clinical performance. To address this, TNTs arrays were grown on Ti-6Al-4V substrates by anodic oxidation in a fluoride-containing electrolyte. Structural characterization confirmed the formation of nanocrystalline Ti₂O with an average crystal size of 21.2 nm, while morphological analysis revealed uniform nanotube arrays with diameters of 85.39 ± 10.7 nm. Nanoindentation assays demonstrated an elastic modulus of 8.034 GPa, closely matching human cortical bone, thereby reducing the risk of stress shielding. In vitro assays using hFOB 1.19 osteoblasts showed that titanium oxide nanotubes (TNTs) surfaces significantly accelerated αVβ3 integrin expression, observed the higher difference at 48 h compared to smooth surfaces. Furthermore, proliferation assays with CFSE revealed enhanced cell division on TNT films, with maximum proliferation observed at 96 h. These findings indicate that anodized titanium oxide nanotube films not only improve the mechanical compatibility of Ti-6Al-4V with bone tissue but also promote integrin-mediated osteoblast adhesion and proliferation. The results highlight the potential of TNT coatings as a promising surface engineering approach for next-generation dental and orthopedic implants.