In this paper, we first describe the basics of the field of cancer diagnosis, which includes steps of cancer diagnosis followed by the typical classification methods used by doctors, providing a historical idea of cancer classification techniques to the readers. These methods include Asymmetry, Border, Color and Diameter (ABCD) method, seven-point detection method, Menzies method, and pattern analysis. They are used regularly by doctors for cancer diagnosis, although they are not considered very efficient for obtaining better performance. Moreover, considering all types of audience, the basic evaluation criteria are also discussed. The criteria include the receiver operating characteristic curve (ROC curve), Area under the ROC curve (AUC), F1 score, accuracy, specificity, sensitivity, precision, dice-coefficient, average accuracy, and Jaccard index. Previously used methods are considered inefficient, asking for better and smarter methods for cancer diagnosis. Artificial intelligence and cancer diagnosis are gaining attention as a way to define better diagnostic tools. In particular, deep neural networks can be successfully used for intelligent image analysis. The basic framework of how this machine learning works on medical imaging is provided in this study, i.e., pre-processing, image segmentation and post-processing. The second part of this manuscript describes the different deep learning techniques, such as convolutional neural networks (CNNs), generative adversarial models (GANs), deep autoencoders (DANs), restricted Boltzmann’s machine (RBM), stacked autoencoders (SAE), convolutional autoencoders (CAE), recurrent neural networks (RNNs), long short-term memory (LTSM), multi-scale convolutional neural network (M-CNN), multi-instance learning convolutional neural network (MIL-CNN). For each technique, we provide Python codes, to allow interested readers to experiment with the cited algorithms on their own diagnostic problems. The third part of this manuscript compiles the successfully applied deep learning models for different types of cancers. Considering the length of the manuscript, we restrict ourselves to the discussion of breast cancer, lung cancer, brain cancer, and skin cancer. The purpose of this bibliographic review is to provide researchers opting to work in implementing deep learning and artificial neural networks for cancer diagnosis a knowledge from scratch of the state-of-the-art achievements.

In this paper, we approach the problem of forecasting a time series (TS) of an electrical load measured on the Azienda Comunale Energia e Ambiente (ACEA) power grid, the company managing the electricity distribution in Rome, Italy, with an echo state network (ESN) considering two different leading times of 10 min and 1 day. We use a standard approach for predicting the load in the next 10 min, while, for a forecast horizon of one day, we represent the data with a high-dimensional multi-variate TS, where the number of variables is equivalent to the quantity of measurements registered in a day. Through the orthogonal transformation returned by PCA decomposition, we reduce the dimensionality of the TS to a lower number k of distinct variables; this allows us to cast the original prediction problem in k different one-step ahead predictions. The overall forecast can be effectively managed by k distinct prediction models, whose outputs are combined together to obtain the final result. We employ a genetic algorithm for tuning the parameters of the ESN and compare its prediction accuracy with a standard autoregressive integrated moving average model.

A high automation degree is one of the most important features of data driven modeling tools and it should be taken into consideration in classification systems design. In this regard, constructive training algorithms are essential to improve the automation degree of a modeling system. Among neuro-fuzzy classifiers, Simpson's (1992) min-max networks have the advantage of being trained in a constructive way. The use of the hyperbox, as a frame on which different membership functions can be tailored, makes the min-max model a flexible tool. However, the original training algorithm evidences some serious drawbacks, together with a low automation degree. In order to overcome these inconveniences, in this paper two new learning algorithms for fuzzy min-max neural classifiers are proposed: the adaptive resolution classifier (ARC) and its pruning version (PARC). ARC/PARC generates a regularized min-max network by a succession of hyperbox cuts. The generalization capability of ARC/PARC technique mostly depends on the adopted cutting strategy. By using a recursive cutting procedure (R-ARC and R-PARC) it is possible to obtain better results. ARC, PARC, R-ARC, and R-PARC are characterized by a high automation degree and allow to achieve networks with a remarkable generalization capability. Their performances are evaluated through a set of toy problems and real data benchmarks. The paper also proposes a suitable index that can be used for the sensitivity analysis of the classification systems under consideration.