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Catherine Norton
Health Research Institute (HRI), University of Limerick, V94 T9PX Limerick, Ireland

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Preprint content
Published: 11 June 2021
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ACS Style

Tala Raad; Anthony Villani; Angeliki Papadaki; Anne Griffin; Catherine Norton; Evangeline Mantzioris; Audrey Tierney. Adherence to a Mediterranean diet among adults in Ireland: a cross-sectional study. 2021, 1 .

AMA Style

Tala Raad, Anthony Villani, Angeliki Papadaki, Anne Griffin, Catherine Norton, Evangeline Mantzioris, Audrey Tierney. Adherence to a Mediterranean diet among adults in Ireland: a cross-sectional study. . 2021; ():1.

Chicago/Turabian Style

Tala Raad; Anthony Villani; Angeliki Papadaki; Anne Griffin; Catherine Norton; Evangeline Mantzioris; Audrey Tierney. 2021. "Adherence to a Mediterranean diet among adults in Ireland: a cross-sectional study." , no. : 1.

Preprint content
Published: 11 June 2021
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Catherine Norton; Clodagh Murphy; Iballa Martinez Yanes. Determining the healthfulness of an Irish Higher Education Institute (HEI) using the Healthy Campus Environment Audit (HCEA) tools. 2021, 1 .

AMA Style

Catherine Norton, Clodagh Murphy, Iballa Martinez Yanes. Determining the healthfulness of an Irish Higher Education Institute (HEI) using the Healthy Campus Environment Audit (HCEA) tools. . 2021; ():1.

Chicago/Turabian Style

Catherine Norton; Clodagh Murphy; Iballa Martinez Yanes. 2021. "Determining the healthfulness of an Irish Higher Education Institute (HEI) using the Healthy Campus Environment Audit (HCEA) tools." , no. : 1.

Journal article
Published: 22 December 2020 in Nutrients
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The revised European consensus defined sarcopenia as a progressive and generalized skeletal muscle disorder that is associated with an increased likelihood of adverse outcomes including falls, fractures, physical disability and mortality. The aim of this study was to determine the prevalence of sarcopenia and analyse the influence of diet, physical activity (PA) and obesity index as risk factors of each criteria of sarcopenia. A total of 629 European middle-aged and older adults were enrolled in this cross-sectional study. Anthropometrics were assessed. Self-reported PA and adherence to the Mediterranean diet were evaluated with the Global Physical Activity Questionnaire (GPAQ) and Prevention with Mediterranean Diet questionnaire (PREDIMED), respectively. The functional assessment included handgrip strength, lower body muscle strength, gait speed and agility/dynamic balance. Of the participants, 4.84% to 7.33% showed probable sarcopenia. Sarcopenia was confirmed in 1.16% to 2.93% of participants. Severe sarcopenia was shown by 0.86% to 1.49% of participants. Male; age group ≤65 years; lower body mass index (BMI); high levels of vigorous PA; and the consumption of more than one portion per day of red meat, hamburgers, sausages or cold cuts and/or preferential consumption of rabbit, chicken or turkey instead of beef, pork, hamburgers or sausages (OR = 0.126–0.454; all p < 0.013) resulted as protective factors, and more time of sedentary time (OR = 1.608–2.368; p = 0.032–0.041) resulted as a risk factor for some criteria of sarcopenia. In conclusion, age, diet, PA, and obesity can affect the risk of having low muscle strength, low muscle mass or low functional performance, factors connected with sarcopenia.

ACS Style

Pablo Marcos-Pardo; Noelia González-Gálvez; Abraham López-Vivancos; Alejandro Espeso-García; Luis Martínez-Aranda; Gemma Gea-García; Francisco Orquín-Castrillón; Ana Carbonell-Baeza; José Jiménez-García; Daniel Velázquez-Díaz; Cristina Cadenas-Sanchez; Emanuele Isidori; Chiara Fossati; Fabio Pigozzi; Lorenzo Rum; Catherine Norton; Audrey Tierney; Ilvis Äbelkalns; Agita Klempere-Sipjagina; Juris Porozovs; Heikki Hannola; Niko Niemisalo; Leo Hokka; David Jiménez-Pavón; Raquel Vaquero-Cristóbal. Sarcopenia, Diet, Physical Activity and Obesity in European Middle-Aged and Older Adults: The LifeAge Study. Nutrients 2020, 13, 8 .

AMA Style

Pablo Marcos-Pardo, Noelia González-Gálvez, Abraham López-Vivancos, Alejandro Espeso-García, Luis Martínez-Aranda, Gemma Gea-García, Francisco Orquín-Castrillón, Ana Carbonell-Baeza, José Jiménez-García, Daniel Velázquez-Díaz, Cristina Cadenas-Sanchez, Emanuele Isidori, Chiara Fossati, Fabio Pigozzi, Lorenzo Rum, Catherine Norton, Audrey Tierney, Ilvis Äbelkalns, Agita Klempere-Sipjagina, Juris Porozovs, Heikki Hannola, Niko Niemisalo, Leo Hokka, David Jiménez-Pavón, Raquel Vaquero-Cristóbal. Sarcopenia, Diet, Physical Activity and Obesity in European Middle-Aged and Older Adults: The LifeAge Study. Nutrients. 2020; 13 (1):8.

Chicago/Turabian Style

Pablo Marcos-Pardo; Noelia González-Gálvez; Abraham López-Vivancos; Alejandro Espeso-García; Luis Martínez-Aranda; Gemma Gea-García; Francisco Orquín-Castrillón; Ana Carbonell-Baeza; José Jiménez-García; Daniel Velázquez-Díaz; Cristina Cadenas-Sanchez; Emanuele Isidori; Chiara Fossati; Fabio Pigozzi; Lorenzo Rum; Catherine Norton; Audrey Tierney; Ilvis Äbelkalns; Agita Klempere-Sipjagina; Juris Porozovs; Heikki Hannola; Niko Niemisalo; Leo Hokka; David Jiménez-Pavón; Raquel Vaquero-Cristóbal. 2020. "Sarcopenia, Diet, Physical Activity and Obesity in European Middle-Aged and Older Adults: The LifeAge Study." Nutrients 13, no. 1: 8.

Review
Published: 19 May 2020 in Nutrients
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The novel coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has engulfed the world, affecting more than 180 countries. As a result, there has been considerable economic distress globally and a significant loss of life. Sadly, the vulnerable and immunocompromised in our societies seem to be more susceptible to severe COVID-19 complications. Global public health bodies and governments have ignited strategies and issued advisories on various handwashing and hygiene guidelines, social distancing strategies, and, in the most extreme cases, some countries have adopted “stay in place” or lockdown protocols to prevent COVID-19 spread. Notably, there are several significant risk factors for severe COVID-19 infection. These include the presence of poor nutritional status and pre-existing noncommunicable diseases (NCDs) such as diabetes mellitus, chronic lung diseases, cardiovascular diseases (CVD), obesity, and various other diseases that render the patient immunocompromised. These diseases are characterized by systemic inflammation, which may be a common feature of these NCDs, affecting patient outcomes against COVID-19. In this review, we discuss some of the anti-inflammatory therapies that are currently under investigation intended to dampen the cytokine storm of severe COVID-19 infections. Furthermore, nutritional status and the role of diet and lifestyle is considered, as it is known to affect patient outcomes in other severe infections and may play a role in COVID-19 infection. This review speculates the importance of nutrition as a mitigation strategy to support immune function amid the COVID-19 pandemic, identifying food groups and key nutrients of importance that may affect the outcomes of respiratory infections.

ACS Style

Ioannis Zabetakis; Ronan Lordan; Catherine Norton; Alexandros Tsoupras. COVID-19: The Inflammation Link and the Role of Nutrition in Potential Mitigation. Nutrients 2020, 12, 1466 .

AMA Style

Ioannis Zabetakis, Ronan Lordan, Catherine Norton, Alexandros Tsoupras. COVID-19: The Inflammation Link and the Role of Nutrition in Potential Mitigation. Nutrients. 2020; 12 (5):1466.

Chicago/Turabian Style

Ioannis Zabetakis; Ronan Lordan; Catherine Norton; Alexandros Tsoupras. 2020. "COVID-19: The Inflammation Link and the Role of Nutrition in Potential Mitigation." Nutrients 12, no. 5: 1466.

Journal article
Published: 01 May 2020 in Applied Physiology, Nutrition, and Metabolism
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Key opinion leaders in sport and exercise nutrition advocate for a personalised and periodised approach to dietary assessment and prescription. However, practice has not advanced to this level, making recommendations from key researchers unexploited in the applied setting. Our objective was to advance traditional nutritional assessment methods (data collection and analysis) of athletic populations to place training and competition stimulus at the core of a personalised, periodised approach. We term this approach peri-training nutrition (PTN). Novelty The PTN assessment allows researchers and practitioners to effect monitor habitual nutritional practices of athletes specific to athlete aims, training adaptation stimuli, and competitive events.

ACS Style

Marta Kozior; Phillip M. Jakeman; Catherine Norton. Peri-training nutrition methods: advancements to dietary assessment in an athletic population. Applied Physiology, Nutrition, and Metabolism 2020, 45, 564 -568.

AMA Style

Marta Kozior, Phillip M. Jakeman, Catherine Norton. Peri-training nutrition methods: advancements to dietary assessment in an athletic population. Applied Physiology, Nutrition, and Metabolism. 2020; 45 (5):564-568.

Chicago/Turabian Style

Marta Kozior; Phillip M. Jakeman; Catherine Norton. 2020. "Peri-training nutrition methods: advancements to dietary assessment in an athletic population." Applied Physiology, Nutrition, and Metabolism 45, no. 5: 564-568.

Journal article
Published: 21 March 2020 in Nutrients
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Background: The aim of this study was to investigate the effect of whey protein supplementation on myofibrillar protein synthesis (myoPS) and muscle recovery over a 7-d period of intensified resistance training (RT). Methods: In a double-blind randomised parallel group design, 16 resistance-trained men aged 18 to 35 years completed a 7-d RT protocol, consisting of three lower-body RT sessions on non-consecutive days. Participants consumed a controlled diet (146 kJ·kg−1·d−1, 1.7 g·kg−1·d−1 protein) with either a whey protein supplement or an isonitrogenous control (0.33 g·kg−1·d−1 protein). To measure myoPS, 400 ml of deuterium oxide (D2O) (70 atom %) was ingested the day prior to starting the study and m. vastus lateralis biopsies were taken before and after RT-intervention. Myofibrillar fractional synthetic rate (myoFSR) was calculated via deuterium labelling of myofibrillar-bound alanine, measured by gas chromatography-pyrolysis-isotope ratio mass spectrometry (GC-Pyr-IRMS). Muscle recovery parameters (i.e., countermovement jump height, isometric-squat force, muscle soreness and serum creatine kinase) were assessed daily. Results: MyoFSR PRE was 1.6 (0.2) %∙d−1 (mean (SD)). Whey protein supplementation had no effect on myoFSR (p = 0.771) or any recovery parameter (p = 0.390–0.989). Conclusions: Over an intense 7-d RT protocol, 0.33 g·kg−1·d−1 of supplemental whey protein does not enhance day-to-day measures of myoPS or postexercise recovery in resistance-trained men.

ACS Style

Robert W. Davies; Joseph J. Bass; Brian P. Carson; Catherine Norton; Marta Kozior; Daniel J. Wilkinson; Matthew S. Brook; Philip J. Atherton; Ken Smith; Philip M. Jakeman. The Effect of Whey Protein Supplementation on Myofibrillar Protein Synthesis and Performance Recovery in Resistance-Trained Men. Nutrients 2020, 12, 845 .

AMA Style

Robert W. Davies, Joseph J. Bass, Brian P. Carson, Catherine Norton, Marta Kozior, Daniel J. Wilkinson, Matthew S. Brook, Philip J. Atherton, Ken Smith, Philip M. Jakeman. The Effect of Whey Protein Supplementation on Myofibrillar Protein Synthesis and Performance Recovery in Resistance-Trained Men. Nutrients. 2020; 12 (3):845.

Chicago/Turabian Style

Robert W. Davies; Joseph J. Bass; Brian P. Carson; Catherine Norton; Marta Kozior; Daniel J. Wilkinson; Matthew S. Brook; Philip J. Atherton; Ken Smith; Philip M. Jakeman. 2020. "The Effect of Whey Protein Supplementation on Myofibrillar Protein Synthesis and Performance Recovery in Resistance-Trained Men." Nutrients 12, no. 3: 845.

Journal article
Published: 19 July 2019 in Nutrients
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The aim of this study was to test the effects of two disparate isonitrogenous, isocaloric pre-exercise feeds on deuterium-oxide (D2O) derived measures of myofibrillar protein synthesis (myoPS) in humans. Methods: In a double-blind parallel group design, 22 resistance-trained men aged 18 to 35 years ingested a meal (6 kcal·kg-1, 0.8 g·kg-1 carbohydrate, 0.2 g·kg-1 fat) with 0.33 g·kg-1 nonessential amino acids blend (NEAA) or whey protein (WHEY), prior to resistance exercise (70% 1RM back-squats, 10 reps per set to failure, 25% duty cycle). Biopsies of M. vastus lateralis were obtained pre-ingestion (PRE) and +3 h post-exercise (POST). The myofibrillar fractional synthetic rate (myoFSR) was calculated via deuterium labelling of myofibrillar-bound alanine, measured by gas chromatography-pyrolysis-isotope ratio mass spectrometry (GC-Pyr-IRMS). Data are a mean percentage change (95% CI). Results: There was no discernable change in myoFSR following NEAA (10(-5, 25) %, p = 0.235), whereas an increase in myoFSR was observed after WHEY (28 (13, 43) %, p = 0.003). Conclusions: Measured by a D2O tracer technique, a disparate myoPS response was observed between NEAA and WHEY. Pre-exercise ingestion of whey protein increased post-exercise myoPS, whereas a NEAA blend did not, supporting the use of NEAA as a viable isonitrogenous negative control.

ACS Style

Robert W. Davies; Joseph J. Bass; Brian P. Carson; Catherine Norton; Marta Kozior; Miryam Amigo-Benavent; Daniel J. Wilkinson; Matthew Brook; Philip J. Atherton; Kenneth Smith; Philip M. Jakeman. Differential Stimulation of Post-Exercise Myofibrillar Protein Synthesis in Humans Following Isonitrogenous, Isocaloric Pre-Exercise Feeding. Nutrients 2019, 11, 1657 .

AMA Style

Robert W. Davies, Joseph J. Bass, Brian P. Carson, Catherine Norton, Marta Kozior, Miryam Amigo-Benavent, Daniel J. Wilkinson, Matthew Brook, Philip J. Atherton, Kenneth Smith, Philip M. Jakeman. Differential Stimulation of Post-Exercise Myofibrillar Protein Synthesis in Humans Following Isonitrogenous, Isocaloric Pre-Exercise Feeding. Nutrients. 2019; 11 (7):1657.

Chicago/Turabian Style

Robert W. Davies; Joseph J. Bass; Brian P. Carson; Catherine Norton; Marta Kozior; Miryam Amigo-Benavent; Daniel J. Wilkinson; Matthew Brook; Philip J. Atherton; Kenneth Smith; Philip M. Jakeman. 2019. "Differential Stimulation of Post-Exercise Myofibrillar Protein Synthesis in Humans Following Isonitrogenous, Isocaloric Pre-Exercise Feeding." Nutrients 11, no. 7: 1657.

Randomized controlled trial
Published: 23 June 2019 in Nutrients
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The diurnal rhythm of bone remodeling suggests nocturnal dietary intervention to be most effective. This study investigated the effect of bedtime ingestion of a calcium-fortified, milk-derived protein matrix (MBPM) or maltodextrin (CON) on acute (0–4 h) blood and 24-h urinary change in biomarkers of bone remodeling in postmenopausal women with osteopenia. In CON, participants received 804 ± 52 mg calcium, 8.2 ± 3.2 µg vitamin D and 1.3 ± 0.2 g/kg BM protein per day. MBPM increased calcium intake to 1679 ± 196 mg, vitamin D to 9.2 ± 3.1 µg and protein to 1.6 ± 0.2 g/kg BM. Serum C-terminal cross-linked telopeptide of type I collagen (CTX) and procollagen type 1 amino-terminal propeptide (P1NP), and urinary N-telopeptide cross-links of type I collagen (NTX), pyridinoline (PYD) and deoxypyridinoline (DPD) was measured. Analyzed by AUC and compared to CON, a −32% lower CTX (p = 0.011, d = 0.83) and 24% (p = 0.52, d = 0.2) increase in P1NP was observed for MBPM. Mean total 24 h NTX excreted in MBPM was −10% (p = 0.035) lower than CON. Urinary PYD and DPD were unaffected by treatment. This study demonstrates the acute effects of bedtime ingestion of a calcium-fortified, milk-based protein matrix on bone remodeling.

ACS Style

Manjula Hettiarachchi; Rachel Cooke; Catherine Norton; Phil Jakeman. Temporal Change in Biomarkers of Bone Turnover Following Late Evening Ingestion of a Calcium-Fortified, Milk-Based Protein Matrix in Postmenopausal Women with Osteopenia. Nutrients 2019, 11, 1413 .

AMA Style

Manjula Hettiarachchi, Rachel Cooke, Catherine Norton, Phil Jakeman. Temporal Change in Biomarkers of Bone Turnover Following Late Evening Ingestion of a Calcium-Fortified, Milk-Based Protein Matrix in Postmenopausal Women with Osteopenia. Nutrients. 2019; 11 (6):1413.

Chicago/Turabian Style

Manjula Hettiarachchi; Rachel Cooke; Catherine Norton; Phil Jakeman. 2019. "Temporal Change in Biomarkers of Bone Turnover Following Late Evening Ingestion of a Calcium-Fortified, Milk-Based Protein Matrix in Postmenopausal Women with Osteopenia." Nutrients 11, no. 6: 1413.

Journal article
Published: 01 October 2018 in Exercise Biochemistry Review
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Objective The aim of this research was the development and validation of a translational model for the evaluation of exercise and nutrient stimulated muscle protein synthesis (MPS). To achieve this overall aim, three primary objectives had to be realised: (i) Development of an in vitro skeletal muscle cell bioassay to measure muscle growth and MPS; (ii) Development of an ex vivo model to evaluate the humoral effect on MPS in response to nutrient feeding and exercise; (iii) Use of a stable isotope technique to evaluate MPS in response to nutrient feeding and exercise in vivo. Methods To develop a novel in vitro skeletal muscle cell bioassay to measure muscle growth and MPS, C2C12 myoblasts were proliferated and subsequently differentiated to myotubes over 8 days in DMEM (2% HS). Changes in cell behavior and adhesion properties were monitored by measuring impedance via interdigitated microelectrodes using the xCELLigence system. MPS was measured by puromycin incorporation using the SUnSET technique, intracellular signalling measured by western blot, and myotube thickness by microscopy. To demonstrate the capability to monitor nutrient regulation of muscle growth, media was conditioned with a known potent regulator of MPS (leucine) in a dose response experiment (0.20 - 2.0 mM). To establish the ability of the bioassay to measure the humoral effect of MPS in response to feeding and exercise, media was conditioned by ex vivo human serum from fasted, rested, fed (protein and isonitrogenous non-essential amino acid (NEAA) control) and post-exercise conditions. To evaluate MPS in response to nutrient feeding and exercise in vivo, acute MPS (5 h) was assessed by measuring stable isotope deuterium oxide (D2O) incorporation into m. vastus lateralis skeletal muscle following consumption of either a Whey Protein (WP) or an isonitrogenous NEAA control combined with resistance exercise in resistance trained males. Results In vitro experiments observed a dose-response effect with a 32 % increase in cell index and a 27 % increase in cell thickness after 2 h in the presence of 2.0 mM leucine when compared with control myotubes. Ex vivo serum following ingestion of NEAA had no effect on protein signalling or MPS whereas WP fed serum significantly increased mTOR, P70S6K and 4E-BP1 phosphorylation (p

ACS Style

Brian Carson; Robert W. Davies; Joseph Bass; Catherine Norton; Bijal Patel; Miryam Amigo-Benavent; Sylvia Murphy; Patrick Kiely; Philip Jakeman. PL - 033 A translational model of muscle protein synthetic bioactivity in vitro, ex vivo and in vivo. Exercise Biochemistry Review 2018, 1, 1 .

AMA Style

Brian Carson, Robert W. Davies, Joseph Bass, Catherine Norton, Bijal Patel, Miryam Amigo-Benavent, Sylvia Murphy, Patrick Kiely, Philip Jakeman. PL - 033 A translational model of muscle protein synthetic bioactivity in vitro, ex vivo and in vivo. Exercise Biochemistry Review. 2018; 1 (1):1.

Chicago/Turabian Style

Brian Carson; Robert W. Davies; Joseph Bass; Catherine Norton; Bijal Patel; Miryam Amigo-Benavent; Sylvia Murphy; Patrick Kiely; Philip Jakeman. 2018. "PL - 033 A translational model of muscle protein synthetic bioactivity in vitro, ex vivo and in vivo." Exercise Biochemistry Review 1, no. 1: 1.

Journal article
Published: 01 May 2018 in Medicine & Science in Sports & Exercise
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Robert W. Davies; Joseph J. Bass; Brian P. Carson; Catherine Norton; Marta Kozior; Matthew S. Brook; Daniel J. Wilkinson; Philip J. Atherton; Ken Smith; Philip M. Jakeman. The Effect of Whey Protein Supplementation on the Recovery of Contractile Function following Resistance Training. Medicine & Science in Sports & Exercise 2018, 50, 839 .

AMA Style

Robert W. Davies, Joseph J. Bass, Brian P. Carson, Catherine Norton, Marta Kozior, Matthew S. Brook, Daniel J. Wilkinson, Philip J. Atherton, Ken Smith, Philip M. Jakeman. The Effect of Whey Protein Supplementation on the Recovery of Contractile Function following Resistance Training. Medicine & Science in Sports & Exercise. 2018; 50 (5S):839.

Chicago/Turabian Style

Robert W. Davies; Joseph J. Bass; Brian P. Carson; Catherine Norton; Marta Kozior; Matthew S. Brook; Daniel J. Wilkinson; Philip J. Atherton; Ken Smith; Philip M. Jakeman. 2018. "The Effect of Whey Protein Supplementation on the Recovery of Contractile Function following Resistance Training." Medicine & Science in Sports & Exercise 50, no. 5S: 839.

Randomized controlled trial
Published: 08 December 2016 in Biogerontology
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The age-related decline in functional capability is preceded by a reduction in muscle quality. The purpose of this study was to assess the combined effects of progressive resistance training (PRT) and protein supplementation beyond habitual intakes on upper leg lean tissue mass (LTM), muscle quality and functional capability in healthy 50–70 years women. In a single-blinded, randomized, controlled design, 57 healthy older women (age 61.1 ± 5.1 years, 1.61 ± 0.65 m, 65.3 ± 15.3 kg) consumed 0.33 g/kg body mass of a milk-based protein matrix (PRO) for 12 weeks. Of the 57 women, 29 also engaged in a PRT intervention (PRO + PRT). In comparison to the PRO group (n = 28), those in the PRO + PRT group had an increase in upper leg LTM [0.04 (95% CI −0.07 to 0.01) kg vs. 0.13 (95% CI 0.08–0.18) kg, P = 0.027], as measured by Dual-energy X-ray absorptiometry; an increase in knee extensor (KE) torque [−1.6 (95% CI −7.3 to 4.4 N m) vs. 10.2 (95% CI 4.3–15.8 N m), P = 0.007], as measured from a maximal voluntary isometric contraction (Con-Trex MJ; CMV AG); and an increase in extended gait speed [-0.01 (95% CI −0.52–0.04) m s−1 vs. 0.10 (95% CI 0.05–0.22) m s−1, P = 0.001] as measured from a maximal 900 m effort. There was no difference between groups in the time taken to complete 5 chair rises or the number of chair rises performed in 30 s (P > 0.05). PRT in healthy older women ingesting a dietary protein supplement is an effective strategy to improve upper leg LTM, KE torque and extended gait speed in healthy older women.

ACS Style

Peter Francis; William Mc Cormack; Clodagh Toomey; Catherine Norton; Jean Saunders; Emmet Kerin; Mark Lyons; Phil Jakeman. Twelve weeks' progressive resistance training combined with protein supplementation beyond habitual intakes increases upper leg lean tissue mass, muscle strength and extended gait speed in healthy older women. Biogerontology 2016, 18, 881 -891.

AMA Style

Peter Francis, William Mc Cormack, Clodagh Toomey, Catherine Norton, Jean Saunders, Emmet Kerin, Mark Lyons, Phil Jakeman. Twelve weeks' progressive resistance training combined with protein supplementation beyond habitual intakes increases upper leg lean tissue mass, muscle strength and extended gait speed in healthy older women. Biogerontology. 2016; 18 (6):881-891.

Chicago/Turabian Style

Peter Francis; William Mc Cormack; Clodagh Toomey; Catherine Norton; Jean Saunders; Emmet Kerin; Mark Lyons; Phil Jakeman. 2016. "Twelve weeks' progressive resistance training combined with protein supplementation beyond habitual intakes increases upper leg lean tissue mass, muscle strength and extended gait speed in healthy older women." Biogerontology 18, no. 6: 881-891.

Randomized controlled trial
Published: 18 November 2015 in The Journal of Nutrition
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Background: Key areas of research on the preservation of lean tissue mass (LTM) during aging are determinations of the protein requirement and optimal protein intake at meals. Objective: The aim of this study was to determine the effect of protein supplementation at breakfast and lunch for 24 wk beyond habitual intakes on whole-body LTM in healthy adults aged 50–70 y. Methods: In a single-blinded, randomized, controlled design, 60 healthy older men and women (aged 61 ± 5 y) with a body mass index (in kg/m2) of 25.8 ± 3.6 consumed either 0.165 g/kg body mass of a milk-based protein matrix (PRO) or an isoenergetic, nonnitrogenous maltodextrin control (CON) at breakfast and midday meals, the lower protein–containing meals of the day, for 24 wk. Dual-energy X-ray absorptiometry was used to measure the change in LTM. Results: After the intervention, protein intake in the PRO group increased from 0.23 ± 0.1 to 0.40 ± 0.1 g/kg for breakfast and from 0.31 ± 0.2 to 0.47 ± 2 g/kg for the midday meal. In response, LTM increased by 0.45 (95% CI: 0.06, 0.83) kg in the PRO group compared with a decrease of 0.16 (95% CI: −0.49, 0.17) kg in the CON group (P = 0.006). Appendicular LTM accounted for the majority of the difference in LTM, increasing by 0.27 (95% CI: 0.05, 0.48) kg in the PRO group compared with no change in the CON group (P = 0.002). Conclusions: Protein supplementation at breakfast and lunch for 24 wk in healthy older adults resulted in a positive (+0.6 kg) difference in LTM compared with an isoenergetic, nonnitrogenous maltodextrin control. These observations suggest that an optimized and balanced distribution of meal protein intakes could be beneficial in the preservation of lean tissue mass in the elderly. This trial was registered at clinicaltrials.gov as NCT02529124.

ACS Style

Catherine Norton; Clodagh Toomey; William McCormack; Peter Francis; Jean Saunders; Emmet Kerin; Philip Jakeman. Protein Supplementation at Breakfast and Lunch for 24 Weeks beyond Habitual Intakes Increases Whole-Body Lean Tissue Mass in Healthy Older Adults. The Journal of Nutrition 2015, 146, 65 -69.

AMA Style

Catherine Norton, Clodagh Toomey, William McCormack, Peter Francis, Jean Saunders, Emmet Kerin, Philip Jakeman. Protein Supplementation at Breakfast and Lunch for 24 Weeks beyond Habitual Intakes Increases Whole-Body Lean Tissue Mass in Healthy Older Adults. The Journal of Nutrition. 2015; 146 (1):65-69.

Chicago/Turabian Style

Catherine Norton; Clodagh Toomey; William McCormack; Peter Francis; Jean Saunders; Emmet Kerin; Philip Jakeman. 2015. "Protein Supplementation at Breakfast and Lunch for 24 Weeks beyond Habitual Intakes Increases Whole-Body Lean Tissue Mass in Healthy Older Adults." The Journal of Nutrition 146, no. 1: 65-69.

Review
Published: 01 January 2015 in Topics in Clinical Nutrition
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ACS Style

Clodagh M. Toomey; Alexandra Cremona; Katie Hughes; Catherine Norton; Phil Jakeman. A Review of Body Composition Measurement in the Assessment of Health. Topics in Clinical Nutrition 2015, 30, 16 -32.

AMA Style

Clodagh M. Toomey, Alexandra Cremona, Katie Hughes, Catherine Norton, Phil Jakeman. A Review of Body Composition Measurement in the Assessment of Health. Topics in Clinical Nutrition. 2015; 30 (1):16-32.

Chicago/Turabian Style

Clodagh M. Toomey; Alexandra Cremona; Katie Hughes; Catherine Norton; Phil Jakeman. 2015. "A Review of Body Composition Measurement in the Assessment of Health." Topics in Clinical Nutrition 30, no. 1: 16-32.

Journal article
Published: 13 June 2013 in International Journal of Dairy Technology
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Sarcopenia has been attributed to a diminished postprandial muscle protein synthetic response. Differences in digestion and absorption kinetics of dietary protein and/or its amino acid composition have been suggested to modulate postprandial muscle protein accretion. The amino acid composition of dairy protein, especially whey, has the potential to confer advantages above other nondairy protein sources in prevention of lean tissue mass loss. This may be attributable to its relative high concentration of the essential amino acid leucine.

ACS Style

Catherine Norton; Philip Jakeman. Towards a Sustainable Dairy Sector: The underappreciated role of dairy protein in the preservation of lean tissue mass in the elderly. International Journal of Dairy Technology 2013, 66, 317 -320.

AMA Style

Catherine Norton, Philip Jakeman. Towards a Sustainable Dairy Sector: The underappreciated role of dairy protein in the preservation of lean tissue mass in the elderly. International Journal of Dairy Technology. 2013; 66 (3):317-320.

Chicago/Turabian Style

Catherine Norton; Philip Jakeman. 2013. "Towards a Sustainable Dairy Sector: The underappreciated role of dairy protein in the preservation of lean tissue mass in the elderly." International Journal of Dairy Technology 66, no. 3: 317-320.