Rising competition for crop usage presents policy challenges exacerbated by poor understanding of where crops are harvested for various uses. Here we create high-resolution global maps showing where crops are harvested for seven broad use categories—food, feed, processing, export, industrial, seed and losses. Yields for food crops are low relative to other crop-use categories. It is unlikely, given current trends, that the minimum calorie requirement to eliminate projected food undernourishment by 2030 will be met through crops harvested for direct food consumption, although enough calories will be harvested across all usages. Sub-Saharan African nations will probably fall short of feeding their increased population and eliminating undernourishment in 2030, even if all harvested calories are used directly as food.

Water is crucial for meeting sustainability targets, but its unsustainable use threatens human wellbeing and the environment. Past assessments of water scarcity (i.e., water demand in exceedance of availability) have often been spatially coarse and temporally limited, reducing their utility for targeting interventions. Here we perform a detailed monthly sub-basin assessment of the evolution of blue (i.e., surface and ground) water scarcity (years 1980-2015) for the world’s three most populous countries – China, India, and the USA. Disaggregating by specific crops and sectors, we find that blue water demand rose by 60% (China), 71% (India), and 27% (USA), dominated by irrigation for a few key crops (alfalfa, maize, rice, wheat). We also find that unsustainable demand during peak months of use has increased by 101% (China), 82% (India), and 49% (USA) and that 32% (China), 61% (India), and 27% (US) of sub-basins experience at least 4 months of scarcity. These findings demonstrate that rising water demands are disproportionately being met by water resources in already stressed regions and provide a basis for targeting potential solutions that better balance the water needs of humanity and nature.

The world is at a crossroad when it comes to agriculture. The global population is growing, and the demand for food is increasing, putting a strain on our agricultural resources and practices. To address this challenge, innovative, sustainable, and inclusive approaches to agriculture are urgently required. In this paper, we launched a call for Essential Questions for the Future of Agriculture and identified a priority list of 100 questions. We focus on 10 primary themes: transforming agri‐food systems, enhancing resilience of agriculture to climate change, mitigating climate change through agriculture, exploring resources and technologies for breeding, advancing cultivation methods, sustaining healthy agroecosystems, enabling smart and controlled‐environment agriculture for food security, promoting health and nutrition‐driven agriculture, exploring economic opportunities and addressing social challenges, and integrating one health and modern agriculture. We emphasise the critical importance of interdisciplinary and multidisciplinary research that integrates both basic and applied sciences and bridges the gaps among various stakeholders for achieving sustainable agriculture.