Background and objectives: The aim of the study was to assess whether there were differences between apparent diffusion coefficient (ADC) values of diffusion-weighted imaging (DWI) and diffusion-weighted imaging with background body signal suppression (DWIBS) sequences in non-prepared and prepared bowels before and after preparation with an enteric hyperosmolar agent, to assess whether ADC measurements have the potential to avoid bowel preparation and whether ADC-DWIBS has advantages over ADC-DWI. Materials and Methods: 106 adult patients without evidence of inflammatory bowel disease (IBD) underwent magnetic resonance (MR) enterography before and after bowel preparation. ADC-DWI and ADC-DWIBS values were measured in the intestinal and colonic walls demonstrating high signal intensity (SI) at DWI tracking images of b = 800 s/mm² before and after preparation. Results: There were significant difference (p < 0.0001) in both ADC-DWI and ADC-DWIBS results between non-prepared and prepared jejunum for DWI being 1.09 × 10⁻³ mm²/s and 1.76 × 10⁻³ mm²/s, respectively, and for DWIBS being 0.91 × 10⁻³ mm²/s and 1.75 × 10⁻³ mm²/s, respectively. Both ADC-DWI and DWIBS also showed significant difference between non-prepared and prepared colon (p < 0.0001), with DWI values 1.41 × 10⁻³ mm²/s and 2.13 × 10⁻³ mm²/s, and DWIBS—1.01 × 10⁻³ mm²/s and 2.04 × 10⁻³ mm²/s, respectively. No significant difference between ADC-DWI and ADC-DWIBS was found in prepared jejunum (p = 0.84) and prepared colon (p = 0.58), whereas a significant difference was found in non-prepared jejunum and non-prepared colon (p = 0.0001 in both samples). Conclusions: ADC between DWI and DWIBS does not differ in prepared bowel walls but demonstrates a difference in non-prepared bowel. ADC in non-prepared bowel is lower than in prepared bowel and possible overlap with the ADC range of IBD is possible in non-prepared bowel. ADC-DWIBS has no advantage over ADC-DWI in regard to IBD assessment.

Background: We compared the efficiency of two MRI diffusion weighted imaging (DWI) techniques: DWI with SPIR (DWI_SPIR) and DWI with STIR (DWI_STIR), to estimate their eligibility for quantitative assessment of Crohn’s disease activity in children and adults. Methods: In inflamed terminal ileum segments (n = 32 in adults, n = 46 in children), Magnetic Resonance Index of Activity (MaRIA) was calculated, ADC values of both DWI techniques were measured, and the corresponding Clermont scores calculated. ADC values of both DWI techniques were compared between both and within each patient group, assessing their mutual correlation. Correlations between MaRIA and the corresponding ADC values, and Clermont scores based on both DWI techniques were estimated. Results: No correlation between ADC of DWI_SPIR and DWI_STIR was observed (rho = 0.27, p = 0.13 in adults, rho = 0.20, p = 0.17 in children). The correlation between MaRIA and Clermont scores was strong in both techniques—in SPIR, rho = 0.93; p < 0.0005 in adults, rho = 0.98, p < 0.0005 in children, and, in STIR, rho = 0.89; p < 0.0005 in adults, rho = 0.95, p < 0.0005 in children. The correlation between ADC and MaRIA was moderate negative for DWI_STIR (rho = 0.93, p < 0.0005 in adults, rho = 0.95, p < 0.0005 in children), but, in DWI_STIR, no correlation between ADC and MaRIA score was observed in adults (rho = −0.001, p = 0.99), whereas children presented low negative correlation (rho = −0.374, p = 0.01). Conclusions: DWI_STIR is not suitable for quantitative assessment of Crohn’s disease activity both in children and adult patients.

The visual search performance of radiologists is systematically challenged due to the use of flat-panel displays when viewing multi-slice images. Three-dimensional visualization of information is expected to facilitate visual search for radiologists. However, as the differences in user performance, depending on radiologist experience, have not yet been assessed for real three-dimensional images, it is difficult to estimate the usability of new visualization systems for radiologists with different amounts of professional search experience. In this study, we aimed to determine how three-dimensional visual search is affected by radiologist experience and the physical properties of stimuli. Radiologists, residents, and medical students accomplished visual search tasks with varying set sizes and target-distractor similarities. Search items were presented on multiple display planes and image manipulation was conducted using a computer keyboard. We compared the search outcome and strategy among three groups of participants. All three groups submitted a similar number of correct responses depending on target-distractor similarity. However, in contrast to radiologists and residents, it took a considerably longer time for students to find the targets. The major differences were evident in search strategy when comparing the image manipulations of radiologists with those of residents and students. Our results demonstrated that experienced radiologists’ search performance benefited from seeing the entire three-dimensional view of an image, whereas residents and students focused instead on reducing the amount of information and searched in a selective manner. These findings should be taken into account when planning the implementation of new workstations with three-dimensional visualization in radiology.