To the Editor—To and colleagues reported the first documented case of an asymptomatic reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after 4.5 months [ 1]. As the patient experienced only mild symptoms during the first episode, the question remains whether a weak immune response after the first episode might explain the reinfection. It has been suggested that patients with an asymptomatic or mild SARS-CoV-2 infection have a weaker immune response because their antibody titers are significantly lower than in patients with pneumonia [ 2]. An estimated 20% do not seroconvert [ 3]. It also remains unclear whether patients can have a symptomatic reinfection. A recent Italian study reported no clinical reinfections within 3 months after hospital discharge [ 4]. We here report a symptomatic reinfection 93 days after a moderate SARS-CoV-2 infection.
In recent years, negative-sense RNA virus classification and taxon nomenclature have undergone considerable transformation. In 2016, the new order Bunyavirales was established, elevating the previous genus Hantavirus to family rank, thereby creating Hantaviridae. Here we summarize affirmed taxonomic modifications of this family from 2016 to 2019. Changes involve the admission of >30 new hantavirid species and the establishment of subfamilies and novel genera based on DivErsity pArtitioning by hieRarchical Clustering (DEmARC) analysis of genomic sequencing data. We outline an objective framework that can be used in future classification schemes when more hantavirids sequences will be available. Finally, we summarize current taxonomic proposals and problems in hantavirid taxonomy that will have to be addressed shortly.
In April 2023, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by one new family, 14 new genera, and 140 new species. Two genera and 538 species were renamed. One species was moved, and four were abolished. This article presents the updated taxonomy of Negarnaviricota as now accepted by the ICTV.