Nanotechnology has become the most effective and rapidly developing field in the area of material science, and silver nanoparticles (AgNPs) are of leading interest because of their smaller size, larger surface area, and multiple applications. The use of plant sources as reducing agents in the fabrication of silver nanoparticles is most attractive due to the cheaper and less time-consuming process for synthesis. Furthermore, the tremendous attention of AgNPs in scientific fields is due to their multiple biomedical applications such as antibacterial, anticancer, and anti-inflammatory activities, and they could be used for clean environment applications. In this review, we briefly describe the types of nanoparticle syntheses and various applications of AgNPs, including antibacterial, anticancer, and larvicidal applications and photocatalytic dye degradation. It will be helpful to the extent of a better understanding of the studies of biological synthesis of AgNPs and their multiple uses.

Background: Colon cancer is aggressive and it causes 0.5 million deaths per year. Practicing natural medicinesfor cancer treatment is safer than conventional drugs. World health organization emphasizes on the importance ofpracticing natural medicines and developing natural product based drugs for cancer treatment. Recently we reportedan anti colon cancer activity associated with pyrogallol isolated from medicinal plant Acacia nilotica in HT-29 cells invitro. To extend our observation in this study we evaluated in vivo colon tumor remission property of acetone extractof A. nilotica (ACE) and pyrogallol. Materials and Methods: In vivo toxicity of ACE and pyrogallol was assessed andIn vivo tumor remission activity of ACE and pyrogallol was determined in murine model. Results: Mice were tolerateddifferent doses of ACE and pyrogallol. Tumor size was considerably reduced in pyrogallol treated mice similar todoxorubicin. Tumor bearing mice treated with ACE and pyrogallol showed mild decline in body weight. Conclusion:Pyrogallol was found to be an effective anti colon cancer agent with less toxicity.