Aleksandra Ratajczak

Dr. Aleksandra Ratajczak

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Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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ASAgnieszka Strzelak
Agnieszka Strzelak
ARAleksandra Ratajczak
Aleksandra Ratajczak
Aleksander AdamiecAleksander Adamiec
Aleksander Adamiec
Wojciech FeleszkoWojciech Feleszko
Wojciech Feleszko
Many studies have been undertaken to reveal how tobacco smoke skews immune responses contributing to the development of chronic obstructive pulmonary disease (COPD) and other lung diseases. Recently, environmental tobacco smoke (ETS) has been linked with asthma and allergic diseases in children. This review presents the most actual knowledge on exact molecular mechanisms responsible for the skewed inflammatory profile that aggravates inflammation, promotes infections, induces tissue damage, and may promote the development of allergy in individuals exposed to ETS. We demonstrate how the imbalance between oxidants and antioxidants resulting from exposure to tobacco smoke leads to oxidative stress, increased mucosal inflammation, and increased expression of inflammatory cytokines (such as interleukin (IL)-8, IL-6 and tumor necrosis factor α ([TNF]-α). Direct cellular effects of ETS on epithelial cells results in increased permeability, mucus overproduction, impaired mucociliary clearance, increased release of proinflammatory cytokines and chemokines, enhanced recruitment of macrophages and neutrophils and disturbed lymphocyte balance towards Th2. The plethora of presented phenomena fully justifies a restrictive policy aiming at limiting the domestic and public exposure to ETS.

ARAleksandra Ratajczak
Aleksandra Ratajczak
PJPiotr Jankowski
Piotr Jankowski
PSPiotr Strus
Piotr Strus
Wojciech FeleszkoWojciech Feleszko
Wojciech Feleszko
Introduction: The use of heat-not-burn tobacco products (HnB) is being adopted increasingly as an alternative to smoking combusted products, primarily cigarettes. Substantial controversy has accompanied their marketing and use in the public health context. In this study, we aimed to consider the probable impacts of HnB tobacco products use on public health. Methods: In May 2019, we conducted a systematic review of 15 studies concerning awareness and use of IQOS (abbrv. I Quit Ordinary Smoking) selected from three databases: Cochrane, PubMed, and Embase regarding public health. Results: All key outcomes varied by smoking status: more young adults who were currently smoking reported being aware of, interested in trying, and prone to trying heat-not-burn tobacco products. Interest in trying HnB products was also present among non-smokers, which raises concerns regarding new smokers. Interestingly, susceptibility to trying IQOS (25.1%) was higher than for traditional cigarettes (19.3%), but lower than for e-cigarettes (29.1%). Conclusions: Present studies suggest that HnB tobacco products have the potential to be a reduced risk product for public health compared to conventional cigarettes, considering indirectly the potential effects on the chronic diseases which are traditionally linked to traditional cigarette use as well as second hand exposure, but further studies are needed to determine whether this potential is likely to be realized. The process of HnB tobacco products becoming increasingly popular is of a global scale. Only small differences between countries on different continents regarding popularity and use of HnB tobacco products have been reported.

8 May 2021 in Vaccines
Verified
Journal Article
Open access
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MGMagdalena Grochowska
Magdalena Grochowska
ARAleksandra Ratajczak
Aleksandra Ratajczak
GZGabriela Zdunek
Gabriela Zdunek
Aleksander AdamiecAleksander Adamiec
Aleksander Adamiec
Pawel WaszkiewiczPawel Waszkiewicz
Pawel Waszkiewicz
Wojciech FeleszkoWojciech Feleszko
Wojciech Feleszko
Despite research conducted worldwide, there is no treatment specifically targeting SARS-CoV-2 infection with efficacy proven by randomized controlled trials. A chance for a breakthrough is vaccinating most of the global population. Public opinion surveys on vaccine hesitancy prompted our team to investigate Polish healthcare workers’ (HCWs) attitudes towards the SARS-CoV-2 and influenza vaccinations. In-person and online surveys of HCWs: doctors, nurses, medical students, and other allied health professionals (n = 419) were conducted between 14 September 2020 and 5 November 2020. In our study, 68.7% of respondents would like to be vaccinated against COVID-19. The safety and efficacy of COVID-19 vaccinations would persuade 86.3% of hesitant and those who would refuse to be vaccinated. 3.1% of all respondents claimed that no argument would convince them to get vaccinated. 61.6% of respondents declared a willingness to receive an influenza vaccination, of which 83.3% were also inclined to receive COVID-19 vaccinations. Although most respondents—62.5% (262/419) indicated they trusted in the influenza vaccine more, more respondents intended to get vaccinated against COVID-19 in the 2020/2021 season. The study is limited by its nonrandom sample of HCWs but provides a preliminary description of attitudes towards SARS-CoV-2 vaccination.

ARAleksandra Ratajczak
Aleksandra Ratajczak
KRKarol Ratajczak
Karol Ratajczak
Wojciech FeleszkoWojciech Feleszko
Wojciech Feleszko
Environmental tobacco smoke (ETS) exposure is considered an important public health issue in pediatric population. In this study, we aimed to investigate parents’ knowledge on side effects of passive smoking and counseling for parental smoking among pediatricians and family practitioners. Participants were biological parents of pediatric patients up to the age of 18 years old who attended Pediatric Hospital of Medical University of Warsaw. The questionnaire included 28 questions and queries on environmental tobacco smoke in children’s environment. Medical students identified potential subjects and handed out previously created questionnaires. In total, 506 parents of children aged 0–18 years old were interviewed; 41% (207/506) of parents were smokers, 23% (114/506) were asked about ETS exposure by their pediatricians and 41% (205/506) by family physicians during routine visits. Only a minority of the respondents confirmed having “no smoking” policy in their car 31% (157/506) or in their households 24% (121/506). All parents believed that passive smoking could cause at least one harmful effect: most common were more frequent respiratory infections (43%), asthma (40%), and low birth weight (37%). Among smoking parents, 38% (78/207) has tried to quit smoking for their child’s health sake; 63% (131/207) of smokers have never been asked to quit smoking by their doctor. Parents’ understanding of passive smoking among children differs from current medical knowledge. Rates of screening and counseling for parental smoking in pediatric and family practices are still unsatisfactory.

31 December 2016 in Archiwum Emigracji
Verified
Journal Article
Open access
PDF file
ARAleksandra Ratajczak
Aleksandra Ratajczak
BETWEEN HISTORY AND RELIGION. CHANGE AS A NARRATIVE FIGURE OF THE FORMATION TALE IN THE WRITING OF JÓZEF CZAPSKI The article is an attempt to analyse the memoir novel by Józef Czapski concerning the years from 1914 to 1932 as a narration based on an outline of an ailment as a moment of change and passage. Examining four narrative situations using a wide biographical and historical context—the Tolstoy shift, and the beginning of the February Revolution, meeting Dmitry Merezhkovsky and in consequence reading Brzozowski’s work, Czapski discovering Proust and Corot and the closing chapters of The Inhuman Lands together with a last glimpse of soviet Russia—are being regarded as phases of shaping the writer’s social, national, sexual and artist identity. The theoretical framework is marked by the assumptions of Paul Ricoeur’s narrative anthropology.