The authors argue that plague should be taken much more seriously by the international health community.

In the fight against arthropod crop pests using plant secondary metabolites, most research has focussed on the identification of bioactive molecules. Several hundred candidate plant species and compounds are now known to have pesticidal properties against a range of arthropod pest species. Despite this growing body of research, few natural products are commercialized for pest management whilst on-farm use of existing botanically-based pesticides remains a small, but growing, component of crop protection practice. Uptake of natural pesticides is at least partly constrained by limited data on the trade-offs of their use on farm. The research presented here assessed the potential trade-offs of using pesticidal plant extracts on legume crop yields and the regulating ecosystem services of natural pests enemies. The application of six established pesticidal plants (Bidens pilosa, Lantana camara, Lippia javanica, Tephrosia vogelii, Tithonia diversifolia, and Vernonia amygdalina) were compared to positive and negative controls for their impact on yields of bean (Phaseolus vulgaris), cowpea (Vigna unguiculata), and pigeon pea (Cajanus cajan) crops and the abundance of key indicator pest and predatory arthropod species. Analysis of field trials showed that pesticidal plant treatments often resulted in crop yields that were comparable to the use of a synthetic pesticide (lambda-cyhalothrin). The best-performing plant species were T. vogelii, T. diversifolia, and L. javanica. The abundance of pests was very low when using the synthetic pesticide, whilst the plant extracts generally had a higher number of pests than the synthetic but lower numbers than observed on the negative controls. Beneficial arthropod numbers were low with synthetic treated crops, whereas the pesticidal plant treatments appeared to have little effect on beneficials when compared to the negative controls. The outcomes of this research suggest that using extracts of pesticidal plants to control pests can be as effective as synthetic insecticides in terms of crop yields while tritrophic effects were reduced, conserving the non-target arthropods that provide important ecosystem services such as pollination and pest regulation. Thus managing crop pests using plant secondary metabolites can be more easily integrated in to agro-ecologically sustainable crop production systems.

Reducing the losses from crop pests will help to increase food availability and boost economic growth in sub-Saharan Africa (SSA). However, the existing crop protection paradigm that relies on synthetic agrochemical pesticides has had only a marginal impact on the productivity of many poor smallholder farmers who constitute a major segment of agriculture in SSA. This is primarily because many of them are not able to afford or access these imported chemicals. A solution to this crop protection problem may be to harness biological resources that are locally available, such as endemic insect natural enemies and indigenous pesticidal plant materials. Two specific examples of this already under development in Africa are the use of the pesticidal plant, Tephrosia vogelii, and the harvesting of the endemic insect baculovirus, Spodoptera exempta nucleopolyhedrovirus (SpexNPV). Both of these can be produced locally and have shown promise in trials as inexpensive and effective tools for pest control in Africa and their use is currently being scaled up and evaluated by African networks of researchers. A focus on these systems illustrates the potential for using locally-available natural resources for improved crop protection in Africa. The consideration of these pesticidal plants and insect natural enemies in the wider context of natural capital that provide valuable ecosystem services (including pest control), will facilitate greater recognition of their true economic and societal worth. While both of these model systems show promise, there are also very significant challenges to be overcome in developing production, supply and marketing systems that are economically viable and sustainable. The regulatory environment must also evolve to accommodate and facilitate the registration of new products and the establishment of appropriate supply chains that share the benefits of these resources equitably with the local communities from which they are harvested.

Since 2007, a spate of rodent outbreaks has led to severe food shortages in Asia, affecting highly vulnerable and food-insecure families. Little has been documented about wildlife-management issues associated with these outbreaks. The aims of the present study were to synthesise what we know about rodent outbreaks in Asia, and identify important gaps in our knowledge. We compiled information from agencies of the United Nations, non-government organisations and the authors. The authors conducted site visits to areas affected by outbreaks of rodent populations, and convened an international conference in October 2009 to share knowledge. Bamboo masting is clearly implicated as the primary cause of the rodent-population outbreaks that led to severe food shortages in Mizoram (India), Chin State (Myanmar), Chittagong Hill Tracts (Bangladesh) and upland provinces of Lao PDR. In Laos, emergency food assistance was required for 85 000–145 000 people. In 2009, high rodent losses occurred also in lowland irrigated rice-based systems in the Philippines, Myanmar and Indonesia, not related to bamboo masting. Asynchronous or aseasonal growing of rice crops was a common element in these outbreaks. In the Ayeyarwaddy delta, Myanmar, 2.6 million rats were collected in 3 months through community activities; this outbreak appeared to be related to an extreme climatic event, Cyclone Nargis. There are two key features of rodent outbreaks that make the future uncertain. First, climate change and extreme climatic events will increase impacts of rodents on agricultural production. Second, there is food-security pressure in some countries to grow three crops per year. Increased cropping intensity will reduce fallow periods and create ideal conditions for rodents to breed nearly continuously. Implications of the research are as follows: (i) rodent outbreaks are a consequence of enhanced reproduction and natural mortality is of minor importance, particularly with rapidly increasing populations; therefore, we need to focus more on methods for disrupting reproduction; (ii) a stronger understanding of the ecology of pest species and community dynamics will enable ecologically sustainable management; (iii) we need landscape approaches that focus on crop synchrony, and timely coordinated community action to manage pest species and conserve desirable species; and (iv) a simple monitoring system can help implement ecologically based rodent management.