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Interfacial debonding is a critical problem in beams strengthened externally by sticking a plate at its soffit. This is mainly due to uncertainty of failure mode when the beam is subjected to bending and boundary constraints. Many analytical solutions are available for pure-shear tests when beams are subjected to thermo-mechanical loads; however, only few studies are available when plated beams are subjected to bending. This paper presents a simple approach to study the combined effects of temperature dependent parameters and thermo-mechanical loads on debonding mechanism, interfacial stress-distribution, development of bond-length and load of debonding. First-order closed-form solutions are proposed to address two possible cases of simply supported beam: roller-ended or pin-ended. Proposed solutions also introduce temperature effects (as thermal strains) within the interfacial adhesive to fill the gap in literature; this is useful to relate the effect of glass-transition point of adhesive with the composite action. The analytical observations are validated with focussed experiments and literature, and verified with continuum-discrete FE model; leading to parametric investigations and key observations. Effects of temperature are defined in terms of reverse- and inverse-actions.
M. Arsalan Khan. Towards progressive debonding in composite RC beams subjected to thermo-mechanical bending with boundary constraints – A new analytical solution. Composite Structures 2021, 274, 114334 .
AMA StyleM. Arsalan Khan. Towards progressive debonding in composite RC beams subjected to thermo-mechanical bending with boundary constraints – A new analytical solution. Composite Structures. 2021; 274 ():114334.
Chicago/Turabian StyleM. Arsalan Khan. 2021. "Towards progressive debonding in composite RC beams subjected to thermo-mechanical bending with boundary constraints – A new analytical solution." Composite Structures 274, no. : 114334.
Consumer behaviour is one of the most important and complex areas of research. It acknowledges the buying behaviour of consumer clusters towards any product, such as life insurance policies. Among various factors, the three most well-known determinants on which human conjecture depends for preferring a product are demographic, economic and psychographic factors, which can help in developing an accurate market design and strategy for the sustainable growth of a company. In this paper, the study of customer satisfaction with regard to a life insurance company is presented, which focused on comparing artificial intelligence-based, data-driven approaches to classical market segmentation approaches. In this work, an artificial intelligence-based decision support system was developed which utilises the aforementioned factors for the accurate classification of potential buyers. The novelty of this paper lies in developing supervised machine learning models that have a tendency to accurately identify the cluster of potential buyers with the help of demographic, economic and psychographic factors. By considering a combination of the factors that are related to the demographic, economic and psychographic elements, the proposed support vector machine model and logistic regression model-based decision support systems were able to identify the cluster of potential buyers with collective accuracies of 98.82% and 89.20%, respectively. The substantial accuracy of a support vector machine model would be helpful for a life insurance company which needs a decision support system for targeting potential customers and sustaining its share within the market.
Mohammad Khan; Farnaz Haider; Ahmed Al-Hmouz; Mohammad Mursaleen. Development of an Intelligent Decision Support System for Attaining Sustainable Growth within a Life Insurance Company. Mathematics 2021, 9, 1369 .
AMA StyleMohammad Khan, Farnaz Haider, Ahmed Al-Hmouz, Mohammad Mursaleen. Development of an Intelligent Decision Support System for Attaining Sustainable Growth within a Life Insurance Company. Mathematics. 2021; 9 (12):1369.
Chicago/Turabian StyleMohammad Khan; Farnaz Haider; Ahmed Al-Hmouz; Mohammad Mursaleen. 2021. "Development of an Intelligent Decision Support System for Attaining Sustainable Growth within a Life Insurance Company." Mathematics 9, no. 12: 1369.
Congestive heart failure is among leading genesis of concern that requires an immediate medical attention. Among various cardiac disorders, left ventricular systolic dysfunction is one of the well known cardiovascular disease which causes sudden congestive heart failure. The irregular functioning of a heart can be diagnosed through some of the clinical attributes, such as ejection fraction, serum creatinine etcetera. However, due to availability of a limited data related to the death events of patients suffering from left ventricular systolic dysfunction, a critical level of thresholds of clinical attributes can not be estimated with higher precision. Hence, this paper proposes a novel pseudo reinforcement learning algorithm which overcomes a problem of majority class skewness in a limited dataset by appending a synthetic dataset across minority data space. The proposed pseudo agent in the algorithm continuously senses the state of the dataset (pseudo environment) and takes an appropriate action to populate the dataset resulting into higher reward. In addition, the paper also investigates the role of statistically significant clinical attributes such as age, ejection fraction, serum creatinine etc., which tends to efficiently predict the association of death events of the patients suffering from left ventricular systolic dysfunction.
Mohammad Farhan Khan; Rajesh Kumar Gazara; Muaffaq M. Nofal; Sohom Chakrabarty; Elham M. A. Dannoun; Rami Al-Hmouz; M. Mursaleen. Reinforcing Synthetic Data for Meticulous Survival Prediction of Patients Suffering From Left Ventricular Systolic Dysfunction. IEEE Access 2021, 9, 72661 -72669.
AMA StyleMohammad Farhan Khan, Rajesh Kumar Gazara, Muaffaq M. Nofal, Sohom Chakrabarty, Elham M. A. Dannoun, Rami Al-Hmouz, M. Mursaleen. Reinforcing Synthetic Data for Meticulous Survival Prediction of Patients Suffering From Left Ventricular Systolic Dysfunction. IEEE Access. 2021; 9 (99):72661-72669.
Chicago/Turabian StyleMohammad Farhan Khan; Rajesh Kumar Gazara; Muaffaq M. Nofal; Sohom Chakrabarty; Elham M. A. Dannoun; Rami Al-Hmouz; M. Mursaleen. 2021. "Reinforcing Synthetic Data for Meticulous Survival Prediction of Patients Suffering From Left Ventricular Systolic Dysfunction." IEEE Access 9, no. 99: 72661-72669.
Nanotechnology has emerged as a field with promising applications in building materials. Nanotechnology-based mortars are examples of such building materials that have widespread applications in the construction industry. The main nanomaterials used in mortars include nano-silica, nano-magnesium oxide, nano-alumina, nano-titanium oxide, nano-zinc oxide, nano-clay, and nano-carbon. This review paper presents a summary of the properties and effects of these nanomaterials on cement mortar in terms of its fresh-state and hard-state properties. The fresh-state properties include the setting time, consistency, and workability, while the hard-state properties include mechanical properties such as compressive, flexural, tensile strengths, as well as the elasticity modulus, in addition to durability properties such as water absorption, shrinkage strain, strength loss due to freeze–thaw cycles, and chloride penetration, among others. Different nanomaterials cause different physical and chemical alterations within the microstructures of cement mortar. Therefore, the microstructural characterization and densification of mortar are discussed in detail at varying temperatures. In general, the involvement of nanomaterials in cement mortar influences the fresh-state properties, enhances the mechanical properties, and impacts the durability properties, while reducing the porosity present in the mortar matrix. Cementitious nanomaterials can create a pathway for the easy injection of binding materials into the internal microstructures of a hydration gel to impact the hydration process at different rates, whereas their non-cementitious counterparts can act as fillers. Furthermore, the research gaps and future outlook regarding the application of nanomaterials in mortar are discussed.
M. Khan; M. Imam; Kashif Irshad; Hafiz Ali; Mohd Hasan; Saiful Islam. Comparative Overview of the Performance of Cementitious and Non-Cementitious Nanomaterials in Mortar at Normal and Elevated Temperatures. Nanomaterials 2021, 11, 911 .
AMA StyleM. Khan, M. Imam, Kashif Irshad, Hafiz Ali, Mohd Hasan, Saiful Islam. Comparative Overview of the Performance of Cementitious and Non-Cementitious Nanomaterials in Mortar at Normal and Elevated Temperatures. Nanomaterials. 2021; 11 (4):911.
Chicago/Turabian StyleM. Khan; M. Imam; Kashif Irshad; Hafiz Ali; Mohd Hasan; Saiful Islam. 2021. "Comparative Overview of the Performance of Cementitious and Non-Cementitious Nanomaterials in Mortar at Normal and Elevated Temperatures." Nanomaterials 11, no. 4: 911.
The geometric and material parameters are seen to directly affect the biomechanical response of cornea, for example in tonometry they are responsible for possible errors in pressure readings (referred to as Goldman IOP or IOPG). Some of the critical geometric parameters include radius, curvature, asphericity and, central and peripheral thicknesses that vary with ethnic origin of specimen. While the material parameters, such as stiffness, viscosity hyper elasticity and anisotropy largely depend on age, genetics and environmental exposure. Therefore, to understand the response of such parameters, experimental strip tests are normally used to characterise the problem. While other studies have identified the response and significance of geometrical parameters on IOP, the current study evaluates the impact of key assumptions made during optimisation through mathematical models. In addition, the assumptions are implemented on a set of experimental data (coupon tests on an Instron machine over expensive inflation test procedures) to obtain stress–strain response of corneal specimens. In addition to outlining the shortcomings in current experimental procedures and theoretical assumptions, possible conclusions are also made to improve the accuracy of the outcome of results: for example, an anisotropic behaviour is significantly reduced or diminished with further improvement in geometrical assumptions and careful clamping procedures. As a result, contrary to current assumptions in literature, it may be argued that the cornea has anisotropy along superior–inferior (vertical) and temporal–nasal (horizontal) directions.
M. Arsalan Khan; Ahmed Elsheikh; Z.H. Rizvi; I. Ahmad Khan. Influence of analytical methods versus clamping procedure on biomechanical response of cornea through experimental strip tests. Materials Today: Proceedings 2020, 44, 4375 -4380.
AMA StyleM. Arsalan Khan, Ahmed Elsheikh, Z.H. Rizvi, I. Ahmad Khan. Influence of analytical methods versus clamping procedure on biomechanical response of cornea through experimental strip tests. Materials Today: Proceedings. 2020; 44 ():4375-4380.
Chicago/Turabian StyleM. Arsalan Khan; Ahmed Elsheikh; Z.H. Rizvi; I. Ahmad Khan. 2020. "Influence of analytical methods versus clamping procedure on biomechanical response of cornea through experimental strip tests." Materials Today: Proceedings 44, no. : 4375-4380.
Eukaryotic initiation factor 2 (eIF2) plays a fundamental role in the regulation of protein synthesis. Investigations have revealed that the regulation of eIF2 is robust against intrinsic uncertainties and is able to efficiently counteract them. The robustness properties of the eIF2 pathway against intrinsic disturbances is also well known. However the reasons for this ability to counteract stresses is less well understood. In this paper, the robustness conferring properties of the eIF2 dependent regulatory system is explored with the help of a mathematical model. The novelty of the work presented in this paper lies in articulating the possible reason behind the inbuilt robustness of the highly engineered eIF2 system against intrinsic perturbations. Our investigations reveal that the robust nature of the eIF2 pathway may originate from the existence of an attractive natural sliding surface within the system satisfying reaching and sliding conditions that are well established in the domain of control engineering.
Mohammad Farhan Khan; Sarah K. Spurgeon; Xing-Gang Yan; Muaffaq M. Nofal; Rami Al-Hmouz. Inbuilt Tendency of the eIF2 Regulatory System to Counteract Uncertainties. IEEE Transactions on NanoBioscience 2020, 20, 35 -41.
AMA StyleMohammad Farhan Khan, Sarah K. Spurgeon, Xing-Gang Yan, Muaffaq M. Nofal, Rami Al-Hmouz. Inbuilt Tendency of the eIF2 Regulatory System to Counteract Uncertainties. IEEE Transactions on NanoBioscience. 2020; 20 (1):35-41.
Chicago/Turabian StyleMohammad Farhan Khan; Sarah K. Spurgeon; Xing-Gang Yan; Muaffaq M. Nofal; Rami Al-Hmouz. 2020. "Inbuilt Tendency of the eIF2 Regulatory System to Counteract Uncertainties." IEEE Transactions on NanoBioscience 20, no. 1: 35-41.
Histogram equalisation (HE) is a widely used image contrast enhancement technique which is less computationally complex, but it fails to preserve the brightness and natural appearance of the remotely sensed images. To overcome these limitations several modifications have been reported in the literature. However, the images processed by most of the methods still suffer with the problems of saturation artifacts and un-even expansion of intensities. This paper proposes a novel fuzzy mapped HE method to overcome the aforementioned limitations by partitioning the histogram into multiple segments, expanding each segment to full dynamic range using fuzzy mapping function, then equalising each segment independently, and finally normalising the combination of equalised segments. The normalisation process is controlled by a non-negative control factor, which requires a training data for its estimation. Experimental results demonstrate that the application of proposed method in the area of remote sensing yields better results than the contemporary methods.
Mohammad Farhan Khan; Ekram Khan; Muaffaq M. Nofal; M. Mursaleen. Fuzzy Mapped Histogram Equalization Method for Contrast Enhancement of Remotely Sensed Images. IEEE Access 2020, 8, 112454 -112461.
AMA StyleMohammad Farhan Khan, Ekram Khan, Muaffaq M. Nofal, M. Mursaleen. Fuzzy Mapped Histogram Equalization Method for Contrast Enhancement of Remotely Sensed Images. IEEE Access. 2020; 8 ():112454-112461.
Chicago/Turabian StyleMohammad Farhan Khan; Ekram Khan; Muaffaq M. Nofal; M. Mursaleen. 2020. "Fuzzy Mapped Histogram Equalization Method for Contrast Enhancement of Remotely Sensed Images." IEEE Access 8, no. : 112454-112461.
The conventional histogram equalisation (CHE), though being simple and widely used technique for contrast enhancement, but fails to preserve the mean brightness and natural appearance of images. Most of the improved histogram equalisation (HE) methods give better performance in terms of one or two metrics and sacrifice their performance in terms of other metrics. In this paper, a novel fuzzy based bi- HE method is proposed which equalises low contrast images optimally in terms of all considered metrics. The novelty of the proposed method lies in selection of fuzzy threshold value using level-snip technique which is then used to partition the histogram into segments. The segmented sub-histograms, like other bi-HE methods, are equalised independently and are combined together. Simulation results show that for wide-range of test images, the proposed method improves the contrast while preserving other characteristics and provides good trade-off among all the considered performance metrics
Mohammad Farhan Khan; Deepali Goyal; Muaffaq M. Nofal; Ekram Khan; Rami Al-Hmouz; Enrique Herrera-Viedma. Fuzzy-Based Histogram Partitioning for Bi-Histogram Equalisation of Low Contrast Images. IEEE Access 2020, 8, 11595 -11614.
AMA StyleMohammad Farhan Khan, Deepali Goyal, Muaffaq M. Nofal, Ekram Khan, Rami Al-Hmouz, Enrique Herrera-Viedma. Fuzzy-Based Histogram Partitioning for Bi-Histogram Equalisation of Low Contrast Images. IEEE Access. 2020; 8 (99):11595-11614.
Chicago/Turabian StyleMohammad Farhan Khan; Deepali Goyal; Muaffaq M. Nofal; Ekram Khan; Rami Al-Hmouz; Enrique Herrera-Viedma. 2020. "Fuzzy-Based Histogram Partitioning for Bi-Histogram Equalisation of Low Contrast Images." IEEE Access 8, no. 99: 11595-11614.
The tumor microenvironment associated with deficiencies in nutrients and oxygen is important in observing the regulation of tumor progression. The aggressiveness of the tumour cells can be stimulated by exposing it to nutrient starvation and hypoxia. During nutrient starvation, activation of integrated stress response pathway takes place, which helps tumor cells to cope with nutrient stress. In this paper, an evolutionarily conserved central translational control pathway, i.e. the integrated stress response pathway is analysed with the help of a mathematical model. The present study is of significant novelty in terms of testable predictions about specific pathway properties with the help of analysis tools from control theory. Investigation has suggested that, both kinases GCN2 and PERK has semi-disparate impact on dynamic control properties of the system. Examples include both kinases show analogous behaviour towards the robustness and stability of the system, but disparate behaviour in compensating the loss of another kinase.
Mohammad Farhan Khan; Sarah K. Spurgeon; Muaffaq M. Nofal; Xing-Gang Yan. Semi-Disparate Impact of Kinases GCN2 and PERK in Modulating the Dynamic Control Properties of eIF2 Pathway. IEEE Access 2019, 7, 68132 -68139.
AMA StyleMohammad Farhan Khan, Sarah K. Spurgeon, Muaffaq M. Nofal, Xing-Gang Yan. Semi-Disparate Impact of Kinases GCN2 and PERK in Modulating the Dynamic Control Properties of eIF2 Pathway. IEEE Access. 2019; 7 (99):68132-68139.
Chicago/Turabian StyleMohammad Farhan Khan; Sarah K. Spurgeon; Muaffaq M. Nofal; Xing-Gang Yan. 2019. "Semi-Disparate Impact of Kinases GCN2 and PERK in Modulating the Dynamic Control Properties of eIF2 Pathway." IEEE Access 7, no. 99: 68132-68139.
The novel BEM for dynamic crack wave interaction problem is presented here. The various concepts, key ideas and theories are discussed in brief. As the theory suggests, cracks behave as stress concentrators and/or stress distributors. Therefore, two parameters associated with these two phenomena are calculated, namely, the Stress Intensity Factor (SIF) that is near–field characteristic and the far–field displacement in the scattered or total wave field. The developed numerical method is validated against the existing analytical solution. Far field crack wave interactions are plotted for perpendicular and inclined wave field. The method captures the complex crack wave interaction with ease.
Zarghaam Haider Rizvi; Mohammad Arsalan Khan; Katrin Sembdner; Syed Faizan Husain. Numerical Modelling of crack wave interaction with BEM. Materials Today: Proceedings 2018, 5, 28253 -28261.
AMA StyleZarghaam Haider Rizvi, Mohammad Arsalan Khan, Katrin Sembdner, Syed Faizan Husain. Numerical Modelling of crack wave interaction with BEM. Materials Today: Proceedings. 2018; 5 (14):28253-28261.
Chicago/Turabian StyleZarghaam Haider Rizvi; Mohammad Arsalan Khan; Katrin Sembdner; Syed Faizan Husain. 2018. "Numerical Modelling of crack wave interaction with BEM." Materials Today: Proceedings 5, no. 14: 28253-28261.
With the limitation of the land availability in major population centers and the availability of the land to be used as waste management sites, incite is required in improving the ground. Many soil stabilization techniques are available using conventional method. Here, we intend to report a method applying the nanotechnology for ground improvement. T-ZnO is used to improve the uniaxial compressive strength of silty-clay at low liquid limit. Silt soil passing 1mm sieve and T-ZnO between 0-5 wt% is used. It was found that with increasing percentage of T-ZnO up to a threshold, a significant improvement in compressive strength is observed which may be attributed to the peculiar tetrapod shape that acts as reinforcement among silt and clay particles.
Zarghaam Haider Rizvi; Nahmed Nissar; M.J. Giri Prasad; Mohammad Arsalan Khan; Syed Faizan Husain; Frank Wuttke. Improvement of Uniaxial Compression of Soil with ZnO tetrapods. Materials Today: Proceedings 2018, 5, 28180 -28185.
AMA StyleZarghaam Haider Rizvi, Nahmed Nissar, M.J. Giri Prasad, Mohammad Arsalan Khan, Syed Faizan Husain, Frank Wuttke. Improvement of Uniaxial Compression of Soil with ZnO tetrapods. Materials Today: Proceedings. 2018; 5 (14):28180-28185.
Chicago/Turabian StyleZarghaam Haider Rizvi; Nahmed Nissar; M.J. Giri Prasad; Mohammad Arsalan Khan; Syed Faizan Husain; Frank Wuttke. 2018. "Improvement of Uniaxial Compression of Soil with ZnO tetrapods." Materials Today: Proceedings 5, no. 14: 28180-28185.
A widely adopted technique for retrofitting of RC beam at soffit is through adhesively sticking external plate of FRP/Steel. However, an increase in applied load leads the plated beam to fail prematurely in debonding and peeling that largely develop from tension region; thereby, compromising the composite action between the plate and the beam that was initially designed to fail in a desired capacity. In recent decades, a significant research has been focussed to understand the influence of premature modes of failure on the capacity of plated beam; however, not much success is achieved in predicted premature failure, which is largely pertaining to complex nature of the materials involved. As premature modes of failure are highly uncertain, the author suggests that any such investigations are not complete without a proper characterisation (qualitative and quantitative) of different modes of failure in terms of their relativ e behaviour and dependency on different parameters. To understand and address these issues, author has proposed a quantitative parameter brittleness of failure that can be used to relate different modes of failure and measure their dependencies on beam parameters. The objective is achieved through a non-linear numerical tool model generated using ABAQUS, with the combination of discrete and continuum models, whose accuracy is validated through literature in terms of modes of failure (behaviour: location, initiation and propagation), load/displacement behaviour and capacity. At interface this was possible by adopting Cohesive Zone Model innovatively such that the same model could be used to define adhesive parameters as well as crack properties; thereby, through this merging technique it is now possible to control interfacial debonding
Mohammad Arsalan Khan. Understanding the Brittleness of Failures in Composite RC beam Plated at Soffit. Materials Today: Proceedings 2018, 5, 24085 -24093.
AMA StyleMohammad Arsalan Khan. Understanding the Brittleness of Failures in Composite RC beam Plated at Soffit. Materials Today: Proceedings. 2018; 5 (11):24085-24093.
Chicago/Turabian StyleMohammad Arsalan Khan. 2018. "Understanding the Brittleness of Failures in Composite RC beam Plated at Soffit." Materials Today: Proceedings 5, no. 11: 24085-24093.
Cracks in clay type soil is a well know problem and has adverse implications in many engineering applications, such as, clay liners, landfill covers, foundations for structures and pavements. Silty clay/ZnO Tetrapod (T-ZnO) nano-geo-composites were prepared with different percentage of T-ZnO between1-5% by weight, by blending the T-ZnO and the soil (direct addition). Fracture toughness of the developed composite is measure through CT test. The results showed that the Tetrapod which has the peculiar shape acts as reinforcement to the clay and silt material offering resistance to deformation and failure. The introduction of the T-ZnO in the soil matrix resulted only in an increase in the fracture toughness of 37% with 1% addition at 17% moisture content, while 30% for the same mixture portion at 19% moisture content. The developed mixture could be applied for clay liners with are susceptible to differential settlement cracks.
Zarghaam Haider Rizvi; Shradha Panda; Mohd Arsalan Khan; Frank Wuttke. Improvement of Fracture toughness of soil with ZnO tetrapod. Materials Today: Proceedings 2018, 5, 18325 -18331.
AMA StyleZarghaam Haider Rizvi, Shradha Panda, Mohd Arsalan Khan, Frank Wuttke. Improvement of Fracture toughness of soil with ZnO tetrapod. Materials Today: Proceedings. 2018; 5 (9):18325-18331.
Chicago/Turabian StyleZarghaam Haider Rizvi; Shradha Panda; Mohd Arsalan Khan; Frank Wuttke. 2018. "Improvement of Fracture toughness of soil with ZnO tetrapod." Materials Today: Proceedings 5, no. 9: 18325-18331.
Steel or FRP plates are adhesively bonded to the external faces of RC beam as a popular technique of retrofitting,; for example, to enhance or improve the load capacity of a beam subjected to an increased traffic load or experiencing a material deterioration with age. However, the overall behaviour of such retrofitted beams is effected by the formation of undesirable cracks, leading to premature failure such as plate debonding and peeling. At this, the designed capacity of plated beam gets significantly affected. While researchers have developed empirical models, fracture mechanics based models and design proposals, the large chunk of which comes from laboratory experiments, yet the capacity of beam under such undesirable modes of failure cannot be accurately predicted due to complex nature of material properties and geometrical discontinuities involved. The experimental work is seen to be restricted due to funding reasons that could accommodate testing of beams over significant number of combinations of material and geometrical parameters involved in practice, as well as to test the effect of boundary conditions. Therefore, it is now proposed to address this problem through a robust numerical tool models validated through literature available against a variety of laboratory experiments. The aim of such tool models would be to predict both the desirable as well as the undesirable modes of failure, and compared with the some design recommendations available on the choice of range of parameters (such as, plate width to thickness ratio). Peeling being considered as the catastrophic mode of failure, the study focuses on the behaviour of particularly this mode of failure and categorising their defining or controlling factors/parameters. It is identified that, like debonding, peeling can also be controlled through a right selection of parameters that significantly affect formation and propagation of flexural crack at plate end to lead to peeling. For example, shorter and/or thicker plates promotes peeling; and higher flexural strength and fracture energy of concrete can avoid peeling.
Mohammad Arsalan Khan; Zarghaam H. Rizvi; Shradha Panda. Effect of Material and Geometrical Parameters on Peeling Rip-off Failure – Numerical Study. Materials Today: Proceedings 2018, 5, 19400 -19409.
AMA StyleMohammad Arsalan Khan, Zarghaam H. Rizvi, Shradha Panda. Effect of Material and Geometrical Parameters on Peeling Rip-off Failure – Numerical Study. Materials Today: Proceedings. 2018; 5 (9):19400-19409.
Chicago/Turabian StyleMohammad Arsalan Khan; Zarghaam H. Rizvi; Shradha Panda. 2018. "Effect of Material and Geometrical Parameters on Peeling Rip-off Failure – Numerical Study." Materials Today: Proceedings 5, no. 9: 19400-19409.
Phosphorylation of eukaryotic translation initiation factor 2 (eIF2) is one of the best studied and most widely used means for regulating protein synthesis activity in eukaryotic cells. This pathway regulates protein synthesis in response to stresses, viral infections, and nutrient depletion, among others. We present analyses of an ordinary differential equation-based model of this pathway, which aim to identify its principal robustness-conferring features. Our analyses indicate that robustness is a distributed property, rather than arising from the properties of any one individual pathway species. However, robustness-conferring properties are unevenly distributed between the different species, and we identify a guanine nucleotide dissociation inhibitor (GDI) complex as a species that likely contributes strongly to the robustness of the pathway. Our analyses make further predictions on the dynamic response to different types of kinases that impinge on eIF2.
Mohammad Farhan Khan; Sarah Spurgeon; Tobias Von Der Haar. Origins of robustness in translational control via eukaryotic translation initiation factor (eIF) 2. Journal of Theoretical Biology 2018, 445, 92 -102.
AMA StyleMohammad Farhan Khan, Sarah Spurgeon, Tobias Von Der Haar. Origins of robustness in translational control via eukaryotic translation initiation factor (eIF) 2. Journal of Theoretical Biology. 2018; 445 ():92-102.
Chicago/Turabian StyleMohammad Farhan Khan; Sarah Spurgeon; Tobias Von Der Haar. 2018. "Origins of robustness in translational control via eukaryotic translation initiation factor (eIF) 2." Journal of Theoretical Biology 445, no. : 92-102.
Mohd Arsalan Khan. Information preserving histogram segmentation of low contrast images using fuzzy measures. Optik 2018, 157, 1397 -1404.
AMA StyleMohd Arsalan Khan. Information preserving histogram segmentation of low contrast images using fuzzy measures. Optik. 2018; 157 ():1397-1404.
Chicago/Turabian StyleMohd Arsalan Khan. 2018. "Information preserving histogram segmentation of low contrast images using fuzzy measures." Optik 157, no. : 1397-1404.
With the advent of research it was identified that material properties are responsible for errors in tonometry pressure (referred to as Goldmann IOP or IOPG) with the stiffening of a composite structure of corneal tissue in particular. Strip tensile tests are conducted to determine their stress–strain relationship for the purpose to study the behaviour of material properties of cornea. Specimens are taken from the superior–inferior (vertical) and temporal– nasal (horizontal) directions. Testing is performed on an Instron machine, under different rate of loading conditions. First set of experiment, with single strain rate, is executed on eyes having random population. While the second set of experiment is executed on eyes of the same animal in both directions, and different strain rates are applied each specimen. Relatively, the first set of experiment is found to be slightly different and less accurate. In general, it is found that the vertical specimen is 34% on an average stiffer than the horizontal specimen compared to Kampmeier et al. of 20% (studied in 2000) and Defu Wang of 15% (studied in 2007). Curve fitting coefficients are also evaluated for 4–degree polynomial. The anisotropy is evident by plotting the ratio of E–tangent value of vertical Ev and horizontal Eh against stresses with individual strain rates. The value of Ev/Eh increases with slightly slow rate with stresses as compared to achieved through slow strain rates.
Mohammad Arsalan Khan; Ahmed Elsheikh; Iqtedar Ahmad Khan. Biomechanical behaviour – Anisotropy of eye cornea through experimental strip tests. IOP Conference Series: Materials Science and Engineering 2018, 310, 012075 .
AMA StyleMohammad Arsalan Khan, Ahmed Elsheikh, Iqtedar Ahmad Khan. Biomechanical behaviour – Anisotropy of eye cornea through experimental strip tests. IOP Conference Series: Materials Science and Engineering. 2018; 310 (1):012075.
Chicago/Turabian StyleMohammad Arsalan Khan; Ahmed Elsheikh; Iqtedar Ahmad Khan. 2018. "Biomechanical behaviour – Anisotropy of eye cornea through experimental strip tests." IOP Conference Series: Materials Science and Engineering 310, no. 1: 012075.
This paper is in closed access until 3rd August 2018.© 2017 Elsevier Ltd Retrofitting of RC beam by gluing a steel plate at the soffit has been a widely adopted technique due to its ease of use, calculations and having minimal variations on structural aesthetics; hence, a large number of such retrofitted structures exist today. However, such structures have also failed frequently due to the formation of premature failures such as peeling and debonding. The further investigations conducted in literature indicated that such undesirable failures can be effected by a large number of geometrical and material parameters. Although, the characterisation and relative influence of such parameters on modes of failures remain unknown; as the past studies have been largely case sensitive or focussing on a small set of parameters. Therefore, to address these issues, a simple but focussed numerical model has been validated through literature for multiple modes of failures over wide range of possible parameters. Further, targeting the response of beam and its critical locations, the authors of this study suggest that the understanding of relative impact of effective parameters, in terms of beam capacity and brittleness of modes of failure, can be broadly utilised to re-evaluate the cause(s) of failure(s) through case studies, or to predict the future of retrofitted structures/beams
Mohammad Arsalan Khan; Jamal El-Rimawi; Vadim V. Silberschmidt. Relative behaviour of premature failures in adhesively plated RC beam using controllable and existing parameters. Composite Structures 2017, 180, 75 -87.
AMA StyleMohammad Arsalan Khan, Jamal El-Rimawi, Vadim V. Silberschmidt. Relative behaviour of premature failures in adhesively plated RC beam using controllable and existing parameters. Composite Structures. 2017; 180 ():75-87.
Chicago/Turabian StyleMohammad Arsalan Khan; Jamal El-Rimawi; Vadim V. Silberschmidt. 2017. "Relative behaviour of premature failures in adhesively plated RC beam using controllable and existing parameters." Composite Structures 180, no. : 75-87.
Realizing the importance of widely used technique of plating for flexural retrofitting of reinforced concrete (RC) beams and its drawbacks due to premature failure(s), present work concentrates in developing a finite element tool model capable of successfully capturing multiple premature failure modes and their corresponding behaviors. The model is simple but focused; the capability and accuracy of the results have been validated through test literature, particularly focusing on the load capacities of beams at progressive stages of failure modes; which is from crack initiation through to complete failure, such as the load of crack initiation, first crack and complete failure. Acceptable accuracy is shown in terms of crack type(s), crack patterns, sequence, location and direction of propagation through the innovative use of cohesive zone model (CZM). The model clearly explains that debonding and peeling, although originating from a same location for most cases, are extensions of different types of cracks.
Mohd Arsalan Khan; Jamal El-Rimawi; Vadim V. Silberschmidt. Numerical Representation of Multiple Premature Failures in Steel-Plated RC Beams. International Journal of Computational Methods 2017, 14, 1 .
AMA StyleMohd Arsalan Khan, Jamal El-Rimawi, Vadim V. Silberschmidt. Numerical Representation of Multiple Premature Failures in Steel-Plated RC Beams. International Journal of Computational Methods. 2017; 14 (4):1.
Chicago/Turabian StyleMohd Arsalan Khan; Jamal El-Rimawi; Vadim V. Silberschmidt. 2017. "Numerical Representation of Multiple Premature Failures in Steel-Plated RC Beams." International Journal of Computational Methods 14, no. 4: 1.
Mohammad Arsalan Khan. Capturing failures in steel-plated RC beams through a combination of discrete and continuum models. Materials Today: Proceedings 2017, 4, 9752 -9757.
AMA StyleMohammad Arsalan Khan. Capturing failures in steel-plated RC beams through a combination of discrete and continuum models. Materials Today: Proceedings. 2017; 4 (9):9752-9757.
Chicago/Turabian StyleMohammad Arsalan Khan. 2017. "Capturing failures in steel-plated RC beams through a combination of discrete and continuum models." Materials Today: Proceedings 4, no. 9: 9752-9757.