Data gathering is a key operator for applications in wireless sensor networks; yet it is also a challenging problem in mobile sensor networks when considering that all nodes are mobile and the communications among them are opportunistic. This paper proposes an efficient data gathering scheme called ADG that adopts speedy mobile elements as the mobile data collector and takes advantage of the movement patterns of the network. ADG first extracts the network meta-data at initial epochs, and calculates a set of proxy nodes based on the meta-data. Data gathering is then mapped into the Proxy node Time Slot Allocation (PTSA) problem that schedules the time slots and orders, according to which the data collector could gather the maximal amount of data within a limited period. Finally, the collector follows the schedule and picks up the sensed data from the proxy nodes through one hop of message transmissions. ADG learns the period when nodes are relatively stationary, so that the collector is able to pick up the data from them during the limited data gathering period. Moreover, proxy nodes and data gathering points could also be timely updated so that the collector could adapt to the change of node movements. Extensive experimental results show that the proposed scheme outperforms other data gathering schemes on the cost of message transmissions and the data gathering rate, especially under the constraint of limited data gathering period.

Human motion tracking is a fundamental building block for various applications including computer animation, human-computer interaction, healthcare, and so on. To reduce the burden of wearing multiple sensors, human motion prediction from sparse sensor inputs has become a hot topic in human motion tracking. However, such predictions are non-trivial as (i) the widely adopted data-driven approaches can easily collapse to average poses, and (ii) the predicted motions contain unnatural jitters. In this work, we address the aforementioned issues by proposing a novel framework which can accurately predict the human joint moving angles from the signals of only four flexible sensors, thereby achieving the tracking of human joints in multi-degrees of freedom. Specifically, we mitigate the collapse to average poses by implementing the model with a Bi-LSTM neural network that makes full use of short-time sequence information; we reduce jitters by adding a median pooling layer to the network, which smooths consecutive motions. Although being bio-compatible and ideal for improving the wearing experience, the flexible sensors are prone to aging which increases prediction errors. Observing that the aging of flexible sensors usually results in drifts of their resistance ranges, we further propose a novel dynamic calibration technique to rescale sensor ranges, which further improves the prediction accuracy. Experimental results show that our method achieves a low and stable tracking error of 4.51 degrees across different motion types with only four sensors.

The last few decades have witnessed an emerging trend of wearable soft sensors; however, there are important signal-processing challenges for soft sensors that still limit their practical deployment. They are error-prone when displaced, resulting in significant deviations from their ideal sensor output. In this work, we propose a novel prototype that integrates an elbow pad with a sparse network of soft sensors. Our prototype is fully bio-compatible, stretchable, and wearable. We develop a learning-based method to predict the elbow orientation angle and achieve an average tracking error of 9.82 degrees for single-user multi-motion experiments. With transfer learning, our method achieves the average tracking errors of 10.98 degrees and 11.81 degrees across different motion types and users, respectively. Our core contributions lie in a solution that realizes robust and stable human joint motion tracking across different device displacements.

DNA methylation is one of the most extensive epigenetic modifications. DNA N6-methyladenine (6mA) plays a key role in many biology regulation processes. An accurate and reliable genome-wide identification of 6mA sites is crucial for systematically understanding its biological functions. Some machine learning tools can identify 6mA sites, but their limited prediction accuracy and lack of robustness limit their usability in epigenetic studies, which implies the great need of developing new computational methods for this problem. In this paper, we developed a novel computational predictor, namely the 6mAPred-MSFF, which is a deep learning framework based on a multi-scale feature fusion mechanism to identify 6mA sites across different species. In the predictor, we integrate the inverted residual block and multi-scale attention mechanism to build lightweight and deep neural networks. As compared to existing predictors using traditional machine learning, our deep learning framework needs no prior knowledge of 6mA or manually crafted sequence features and sufficiently capture better characteristics of 6mA sites. By benchmarking comparison, our deep learning method outperforms the state-of-the-art methods on the 5-fold cross-validation test on the seven datasets of six species, demonstrating that the proposed 6mAPred-MSFF is more effective and generic. Specifically, our proposed 6mAPred-MSFF gives the sensitivity and specificity of the 5-fold cross-validation on the 6mA-rice-Lv dataset as 97.88% and 94.64%, respectively. Our model trained with the rice data predicts well the 6mA sites of other five species: Arabidopsis thaliana, Fragaria vesca, Rosa chinensis, Homo sapiens, and Drosophila melanogaster with a prediction accuracy 98.51%, 93.02%, and 91.53%, respectively. Moreover, via experimental comparison, we explored performance impact by training and testing our proposed model under different encoding schemes and feature descriptors.

DNA methylation is one of the most extensive epigenetic modifications. DNA 4mC modification plays a key role in regulating chromatin structure and gene expression. In this study, we proposed a generic 4mC computational predictor, namely, 4mCPred-MTL using multi-task learning coupled with Transformer to predict 4mC sites in multiple species. In this predictor, we utilize a multi-task learning framework, in which each task is to train species-specific data based on Transformer. Extensive experimental results show that our multi-task predictive model can significantly improve the performance of the model based on single task and outperform existing methods on benchmarking comparison. Moreover, we found that our model can sufficiently capture better characteristics of 4mC sites as compared to existing commonly used feature descriptors, demonstrating the strong feature learning ability of our model. Therefore, based on the above results, it can be expected that our 4mCPred-MTL can be a useful tool for research communities of interest.

The multi-objective evolutionary algorithm optimization (MOEA) is a challenging but critical approach for tackling complex data analysis problems. However, prevailing MOEAs often rely on single strategies to obtain optimal solutions, leading to concerns such as premature convergence and insufficient population diversity, particularly in high-dimensional data scenarios. In this paper, we propose a novel adversarial population generation algorithm, APG-SMOEA, which synergistically combines the benefits of MOEAs and Generative Adversarial Networks (GANs) to address these limitations. In order to balance the efficiency and quality of offspring selection, we introduce an adaptive population entropy strategy, which includes control parameters based on population entropy and a learning pool for storing and retrieving optimal solutions. Additionally, we attempt to alleviate the training complexity and model collapse problems common in GANs with APG-SMOEA. Experimental results on benchmarks demonstrate that the proposed algorithm is superior to the existing algorithms in terms of solution quality and diversity of low-dimensional or high-dimensional complex data.