The knowledge of the plants that are used may provide insight on their properties for further exploration. This study aimed to identify and collect data about medicinal plants used in traditional medicine by the population of the provincial region of Taza, Morocco. An ethnobotanical survey was carried out among 200 informants, competent villagers, herbalists, and traditional healers from the provincial region of Taza city through direct interviews using a structured questionnaire. The survey reported 55 plant species belonging to 28 families used in the folk medicine. Informants results showed that the most frequently used plants were Origanum compactum, Mentha pulegium, Rosmarinus officinalis L., Aloysia citrodora, Calamintha officinalis Moench, and Artemisia herba-alba Asso., with a relative frequency of citation of 76, 72, 60, 42, 40, and 30, respectively. Moreover, in this study, the Lamiaceae family was the most commonly reported plant family, and the leaves were the most frequently used parts of the plants; otherwise, decoction and infusion were the most used modes in the preparation of remedies from medicinal plants in the traditional medicine. The sociodemographic characteristics showed that women use medicinal plants slightly more than men, the illiterate people use the medicinal plant the most, and old people have more information about the medicinal plants than the new generations. The region of Taza of Morocco has an important floristic biodiversity of medicinal plants which are used in traditional medicine practice. This result provides a good database for pharmacological screening in the search for new plants that can contain new bioactive molecules that can be used as a bioactive ingredient of medicament or as a biological alternative in pharmacology.

Latifa Doudach, Hanae Naceiri Mrabti, Samiah Hamad Al-Mijalli, Mohamed Reda Kachmar, Kaoutar Benrahou, Hamza Assaggaf, Ahmed Qasem, Emad Mohamed Abdallah, Bodour Saeed Rajab, Khouloud Harraqui, Mouna Mekkaoui, Abdelhakim Bouyahya, Moulay El Abbes Faouzi. J Pharmacopuncture 2023;26:27-37. https://doi.org/10.3831/KPI.2023.26.1.27

Erodium guttatum is widely used in folk medicine in many countries to treat various ailments such as urinary inflammation, diabetes, constipation, and eczema. The aim of this study is the determination of mineral and phenolic compounds of E. guttatum extracts as well as the investigation of their antidiabetic and antioxidant properties. The mineral composition was determined by the methods of inductively coupled plasma atomic emission spectroscopy analysis. Phytochemical contents of total polyphenols, total flavonoids, and catechic tannins were estimated by colorimetric dosages. The phenolic composition was identified by high‐resolution mass spectrometry (HRMS) analysis. The antioxidant activity of E. guttatum extracts was measured in vitro by five methods (DPPH, ABTS, FRAP, H₂O₂, and xanthine oxidase) and in vivo by assaying the malondialdehyde marker (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH). The obtained results showed that the root plant material is rich in minerals such as k, Ca, and Mg. The methanolic extract of E. guttatum is the richest in polyphenols (389.20 ± 1.55 mg EAG/gE), tannins (289.70 ± 3.57 mg EC/gE), and flavonoids (432.5 ± 3.21 mg ER/gE). Concerning the ESI‐HRMS analysis, it showed the presence of numerous bioactive compounds, including shikimic acid, rottlerine, gallic acid, and vanillic acid. Moreover, the aqueous and alcoholic extracts of E. guttatum exhibited antiradical and antioxidant activity in five tests used, with the best effect of the methanolic extract. Moreover, findings showed that in vivo investigations confirmed those obtained in vitro. On the other hand, E. guttatum showed important antidiabetic effects in vivo. Indeed, diabetic mice treated with extracts of E. guttatum were able to significantly reduce MDA levels and increase the secretion of enzymatic and nonenzymatic antioxidants (SOD, CAT, and GSH, respectively). However, the antioxidant activity of the extracts might be attributed to the abundance of bioactive molecules; as results, this work serves as a foundation for additional pharmacological research.

Background/Objectives: The use of dietary supplements (DSs) has become common among fitness enthusiasts, aiming to enhance performance, recovery, and overall well-being. Methods: A cross-sectional study was conducted in the city of Beni Mellal from April to July 2024, assessed dietary practices, motivations for supplement use, and associated adverse effects among 420 survey participants. Results: The majority of dietary supplement users were aged 25–64 and had higher education levels. Colopathy (67.38%) was the most common eating disorder, followed by digestive (59.46%), inflammatory, and rheumatic diseases (53.50%). Dietary supplementation prevalence was 88.1%, with proteins (60.81%), medicinal plants (45.13%), and vitamins (42.70%) being the most consumed. Key motivations included supporting muscle, bone, and joint strength (musculoskeletal) (83.78%) and enhancing heart and lung function for cardiorespiratory health (82.43%). However, 28% of protein users experienced adverse effects, such as myalgia, gastralgia, palpitations, and insomnia. Multivariate linear regression indicated a significant negative association of creatine with effectiveness (β = −0.485, p = 0.001). Conclusions: Overall, while the benefits of dietary and sports practices are evident, the adverse effects associated with protein supplements highlight the necessity for enhanced nutrivigilance and nutritional education to ensure safe supplements.