Medical image quality assessment (MIQA) is vital in medical imaging and directly affects diagnosis, patient treatment, and general clinical results. Accurate and high-quality imaging is necessary to make accurate diagnoses, efficiently design treatments, and consistently monitor diseases. This review summarizes forty-two research studies on diverse MIQA approaches and their effects on performance in diagnostics, patient results, and efficiency in the process. It contrasts subjective (manual assessment) and objective (rule-driven) evaluation methods, underscores the growing promise of machine intelligence and machine learning (ML) in MIQA automation, and describes the existing MIQA challenges. AI-powered tools are revolutionizing MIQA with automated quality checks, noise reduction, and artifact removal, producing consistent and reliable imaging evaluation. Enhanced image quality is demonstrated in every examination to improve diagnostic precision and support decision making in the clinic. However, challenges still exist, such as variability in quality and variability in human ratings and small datasets hindering standardization. These must be addressed with better-quality data, low-cost labeling, and standardization. Ultimately, this paper reinforces the need for high-quality medical imaging and the potential of MIQA with the power of AI. It is crucial to advance research in this area to advance healthcare.

This study presents a comprehensive comparison of U-Net variants with different backbone architectures for Macular Hole (MH) segmentation in optical coherence tomography (OCT) images. We evaluated eleven architectures, including U-Net combined with InceptionNetV4, VGG16, VGG19, ResNet152, DenseNet121, EfficientNet-B7, MobileNetV2, Xception, and Transformer. Models were assessed using the Dice coefficient and HD95 metrics on the OIMHS dataset. While HD95 proved unreliable for small regions like MH, often returning ‘nan’ values, the Dice coefficient provided consistent performance evaluation. InceptionNetV4 + U-Net achieved the highest Dice coefficient (0.9672), demonstrating superior segmentation accuracy. Although considered state-of-the-art, Transformer + U-Net showed poor performance in MH and intraretinal cyst (IRC) segmentation. Analysis of computational resources revealed that MobileNetV2 + U-Net offered the most efficient performance with minimal parameters, while InceptionNetV4 + U-Net balanced accuracy with moderate computational demands. Our findings suggest that CNN-based backbones, particularly InceptionNetV4, are more effective than Transformer architectures for OCT image segmentation, with InceptionNetV4 + U-Net emerging as the most promising model for clinical applications.

This study introduces a framework for estimating the optical scattering properties of thin-film phantoms using a custom-built Spectral-Domain Dental Optical Coherence Tomography (DEN-OCT) system operating within the 780–900 nm spectral range. The purpose of this work was to assess the performance of this system. The system exhibited high depth-resolved imaging performance with an axial resolution of approximately 16.30 µm, a signal-to-noise ratio of about 32.4 dB, and a 6 dB sensitivity roll-off depth near 2 mm, yielding an effective imaging range of 2.5 mm. Thin-film phantoms with controlled optical characteristics were fabricated and analyzed using Beer–Lambert and diffusion approximation models to evaluate attenuation behavior. Samples representing different tissue analogs demonstrated distinct scattering responses: one sample showed strong scattering similar to hard tissues, while the others exhibited lower scattering and higher transmission, resembling soft-tissue properties. Spectrophotometric measurements at 840 nm supported these trends through characteristic transmittance and reflectance profiles. While homogeneous samples conformed to analytical models, the highly scattering sample deviated due to structural non-uniformity, requiring Monte Carlo simulation to accurately describe photon transport. OCT A-scan analyses fitted with exponential decay models produced attenuation coefficients consistent with spectrophotometric data, confirming the dominance of scattering over absorption. The integration of OCT imaging, optical modeling, and Monte Carlo simulation establishes a reliable methodology for quantitative scattering estimation and demonstrates the potential of the developed DEN-OCT system for advanced dental and biomedical imaging applications. The innovation of this work lies in the integration of phantom-based optical calibration, multi-model scattering analysis, and depth-resolved OCT signal modeling, providing a validated pathway for quantitative parameter extraction in dental OCT applications.