The use of nanotechnology has the potential to revolutionize the detection and treatment of cancer. Developments in protein engineering and materials science have led to the emergence of new nanoscale targeting techniques, which offer renewed hope for cancer patients. While several nanocarriers for medicinal purposes have been approved for human trials, only a few have been authorized for clinical use in targeting cancer cells. In this review, we analyze some of the authorized formulations and discuss the challenges of translating findings from the lab to the clinic. This study highlights the various nanocarriers and compounds that can be used for selective tumor targeting and the inherent difficulties in cancer therapy. Nanotechnology provides a promising platform for improving cancer detection and treatment in the future, but further research is needed to overcome the current limitations in clinical translation. Graphical Abstract

This study inspects the viability of engaging the discarded paper wastes in concrete by varying the volume proportions from 0%–20% with each 5% increment in replacement of the weight of cement. A physiomechanical study was conducted, and the results were presented. A glass fiber reinforced rectangular slab with a longer span (l_y) to shorter span (l_x) ratio of (l_y:l_x) 1.16 was cast with optimum replacement of waste‐paper mass and compared the force‐deformation characteristics with the conventional concrete slab without waste paper. The optimum percentage of discarded papers for the replacement of cement is 5%. Also, the results imply that the compressive strength at the age of 28 days is 30% improved for the optimum replacement. Based on the outcomes of the investigation, it can be inferred that the compressive strength gets progressively reduced if the volume of the discarded paper gets increases. The incorporation of glass fibers improves the split and flexural strength of the concrete specimens considerably. The ultimate load‐carrying capacity of the glass fiber reinforced waste paper incorporated concrete slab measured 42% lower than that of the conventional slab. However, development of the new type of concrete incorporating waste papers is the new trend in ensuring the sustainability of construction materials.

This study explores the durability of green cementitious material of geopolymer concrete. Geopolymer concrete is produced from the polycondensation reaction of aluminosilicate materials (fly ash, Ground Granulated Blast furnace Slag (GGBS)) with alkaline activator solutions. Geopolymer concrete has excellent mechanical properties and its production requires low energy and results in low levels of CO₂ emission. Due to the high demand for river sand, manufactured sand is used as a replacement material in geopolymer concrete under ambient curing conditions. In this study, the durability of G30 grade geopolymer concrete has been investigated using tests acid resistance, water absorption, sulphate resistance, Rapid Chloride Penetration Test (RCPT), and rate of absorption (Sorptivity) test. The sulphuric acid, sodium sulphate, and water absorption tests were carried out at 28 days, 56 days, and 90 days for both the geopolymer and the conventional concrete. The reduction percentage in water absorption and compressive strength loss was found to be better in geopolymer concrete than in conventional concrete. Geopolymer concrete’s chloride penetrability and rate of absorption were analogous to conventional concrete. Regression analysis for geopolymer and conventional concretes in the rate of absorption test showed a good relationship between absorption and the square root of time.

As a technique of producing fabric engineering scaffolds, three-dimensional (3D) printing has tremendous possibilities. 3D printing applications are restricted to a wide range of biomaterials in the field of regenerative medicine and tissue engineering. Due to their biocompatibility, bioactiveness, and biodegradability, biopolymers such as collagen, alginate, silk fibroin, chitosan, alginate, cellulose, and starch are used in a variety of fields, including the food, biomedical, regeneration, agriculture, packaging, and pharmaceutical industries. The benefits of producing 3D-printed scaffolds are many, including the capacity to produce complicated geometries, porosity, and multicell coculture and to take growth factors into account. In particular, the additional production of biopolymers offers new options to produce 3D structures and materials with specialised patterns and properties. In the realm of tissue engineering and regenerative medicine (TERM), important progress has been accomplished; now, several state-of-the-art techniques are used to produce porous scaffolds for organ or tissue regeneration to be suited for tissue technology. Natural biopolymeric materials are often better suited for designing and manufacturing healing equipment than temporary implants and tissue regeneration materials owing to its appropriate properties and biocompatibility. The review focuses on the additive manufacturing of biopolymers with significant changes, advancements, trends, and developments in regenerative medicine and tissue engineering with potential applications.