Nano aluminum oxide was prepared by the combustion method using aluminum nitrate as the oxidizer and urea as a fuel. Characterization of synthesized materials was performed using SEM (scanning electron microscope), powder XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy), and TEM (transmission electron microscope). Al-Mg/Al₂O₃ (2, 4, 6, and 8 wt%) metal matrix nanocomposites were prepared by liquid metallurgy route-vertex technique. The homogeneous dispersion of nano Al₂O₃ particles in Al-Mg/Al₂O₃ metal matrix nanocomposites (MMNCs) was revealed from the field emission SEM analysis. The reinforcement particles present in the matrix were analyzed through energy-dispersive X-ray spectroscopy method. The properties (corrosion and mechanical) of the fabricated composites were evaluated. The mechanical and corrosion properties of the prepared nanocomposites initially increased and then decreased with the addition of nano Al₂O₃ particles in Al-Mg Matrix. The studies show that, the presence of 6 wt% of nano Al₂O₃ particles in the matrix improved the properties of other combinations of nano Al₂O₃ in the Al-Mg matrix material. Further, the Al-Mg/Al₂O₃ (6 wt%) MMNCs are joined by friction stir welding and evaluated for microstructural, mechanical, and corrosion properties. Al-Mg/Al₂O₃ MMNCs may find applications in the marine field. The response surface method (RSM) was used for the optimization of tensile strength, Young’s modulus, and microhardness of the synthesized material which resulted in a 95% of statistical confidence level. Artificial neural network (ANN) analysis was also carried out which perfectly predicted these two properties. The ANN model is optimized to obtain 99.9% accurate predictions by changing the number of neurons in the hidden layer.