Background: Emerging evidence highlights the role of physical exercise as a non-pharmacological intervention for reducing symptoms of anxiety and depression. While most research has focused on aerobic modalities and chronic training programs, the acute psychological impact of resistance training (RT)—particularly in healthy, active individuals—remains underexplored. This study addresses this gap by evaluating the immediate effects of a single RT session on anxiety and depression in healthy, active individuals. Methods: Fifty-six healthy, physically active participants (43 males, 13 females; M age = 24.41 ± 4.41 years) were randomly assigned to an experimental group (RT, n = 30) or a control group (stretching/mobility, n = 26). The RT session included multi-joint exercises performed at 70–75% 1RM, while the control session consisted of non-load-based mobility and flexibility exercises. Psychological responses were measured immediately before and five minutes after the session using the Hospital Anxiety and Depression Scale (HADS), which includes subscales for anxiety (HADS-A) and depression (HADS-D). Results: Non-parametric within-group analysis (Wilcoxon Signed-Rank Test) revealed a significant reduction in anxiety scores in the RT group (Z = −3.3, p < 0.001, r = −0.7), and a moderate but significant decrease in depression (Z = −2.8, p = 0.005, r = −0.6). No significant changes were observed in the control group for either variable. Between-group comparisons (Mann–Whitney U) showed significantly greater reductions in anxiety in the RT group (p = 0.021), while differences in depression deltas were not significant. A Quade ANCOVA confirmed that group assignment is significantly predictive for post-intervention anxiety levels (F(1, 54) = 8.46, p = 0.005), controlling for baseline values. Conclusions: A single session of moderate-to-high-intensity resistance training can acutely reduce anxiety symptoms in healthy physically active individuals. The effect on depressive symptoms appears more modest and variable, suggesting differential sensitivity to acute exercise stimuli. These findings support the use of RT not only for long-term psychological health but also as a feasible short-term intervention for emotional regulation in healthy active populations.

Background: Chronic musculoskeletal pain (CMP) is a multidimensional condition involving both peripheral and central mechanisms, with increasing evidence supporting an interplay between subjective pain perception and autonomic nervous system (ANS) function. However, few studies have explored whether a single non-invasive intervention can concurrently modulate both domains. Objectives: To evaluate the short-term effects of a single session of Pulsed Electromagnetic Field (PEMF) therapy—administered via the PAP Ion Magnetic Induction (PAPIMI™) device—on subjective pain intensity and heart rate variability (HRV) parameters in individuals with CMP. The relationship between perceived pain relief and physiological autonomic adaptations was also explored. Methods: Thirty adults with CMP underwent a single PAPIMI™ session. Subjective pain intensity was measured using the Numeric Pain Rating Scale (NPRS), while autonomic function was assessed via HRV. Pre- to post-intervention changes were analyzed using the Wilcoxon Signed-Rank test, while Spearman’s correlation was computed to assess associations between post-intervention changes in subjective perceived pain and HRV parameters. Results: A significant reduction in NPRS scores (p < 0.001) was found after PAPIMI intervention. Also, a significant increase in specific parasympathetic-related HRV indices, namely, RMSSD (p = 0.015) and HF power (p = 0.029), was observed. No significant correlations were found between post-intervention changes in pain perception and HRV metrics. Conclusions: A single PAPIMI session induced both analgesic effects and improvements in autonomic balance in individuals with CMP. These findings underscore the potential of PAPIMI as a non-pharmacological approach for rapid pain modulation and systemic rebalancing.

Background: Biological maturation is a major determinant of physical performance in youth football, although the previous evidence suggests that training context may influence maturation–performance associations. This study investigated the association between biological maturation and physical performance in youth football players from professional and non-professional settings. Methods: A total of 302 male football players (Under-10 to Under-14) from a professional academy (n = 122) and non-professional clubs (n = 180) participated. Biological maturation was estimated using maturity offset and age at peak height velocity (aPHV). Physical performance was assessed through standing broad jump, T-test agility, and sit-and-reach tests. General Linear Models and stratified correlation analyses were used to examine the interaction between maturation, age category, and training environment. Relative age distribution was also described. Results: Professional academy players demonstrated superior explosive power, agility, and flexibility across most age categories compared with non-professional players. Significant associations between biological maturation and physical performance were observed mainly in the non-professional environment, particularly for agility and explosive power, whereas few significant relationships emerged in the professional academy. Significant interactions between training environment, age category, and maturation status were found for all performance measures, with the strongest effect observed for agility. A relative age effect emerged only in the older professional categories. Conclusions: Associations between biological maturation and physical performance differed according to training environment in youth football players. Stronger maturation–performance relationships were generally observed in non-professional settings, whereas weaker associations emerged in the professional academy. However, due to the cross-sectional design and the likely interdependence between maturation, selection, and training exposure, causal interpretations cannot be inferred.