Aim: To synthesize current evidence on oral health conditions in individuals with AD and to discuss stage‐specific dental management strategies, including caregiver involvement, from a life‐course perspective. Methods: A comprehensive literature search was conducted in PubMed/MEDLINE, Scopus, Scielo, and Web of Science using MeSH and free‐text terms related to Alzheimer's disease, oral health, and caregivers, with no language or time restrictions. Results: Individuals with AD commonly present with periodontal disease, root caries, xerostomia, traumatic mucosal lesions, and prosthesis‐related complications. The available evidence does not strongly support a bidirectional causal relationship; instead, poor oral health and AD appear to be cumulative conditions influenced by shared antecedent factors, such as biological aging and chronic inflammation. Functional dependence and behavioral symptoms further contribute to oral deterioration over time. Effective dental care therefore requires stage‐adapted approaches, ranging from preventive and restorative interventions in early stages to palliative strategies focused on infection control and comfort in advanced disease. Conclusion: Oral health care for individuals with AD should be grounded in a life‐course and biopsychosocial framework, prioritizing realistic, stage‐specific clinical management and structured caregiver support within interdisciplinary geriatric care.

This in vitro study evaluated the effects of brushing with activated charcoal powder or toothpaste on enamel surface properties, including color change (ΔE), Knoop microhardness (HK), roughness (Ra), and the characteristics of the resulting brushing slurry [pH, fluoride (F⁻), and calcium (Ca²⁺) concentration]. A total of 48 enamel samples were stained and divided into 4 groups (n = 12): activated charcoal toothpaste (AC-T), activated charcoal powder (AC-P), hydrogen peroxide-based whitening toothpaste (HP-T), and conventional toothpaste (C-T, positive control). The samples were subjected to a brushing cycling model, and ΔE, HK, Ra and enamel morphology were analyzed at baseline (T0) and after brushing cycle (T1). Additionally, the pH, soluble F⁻, and Ca²⁺ concentrations of the slurry were analyzed. Data were analyzed using ANOVA/Tukey and paired t-tests (α = 0.05). After brushing, AC-T and AC-P (p < 0.05) showed a decrease in HK, an increase in Ra, and no ΔE variation was observed between groups (p = 0.163). All products had alkaline slurries (>7), and AC-P had no detectable F⁻ (p = 0.00) with significantly higher calcium loss (p = 0.015). Fewer enamel topographical changes were observed in C-T. In conclusion, brushing with CA toothpowder and toothpaste does not promote color change, but toothpowder increases surface Ra, decreases enamel HK, lacks F⁻, and causes greater Ca²⁺ loss.

Antirreabsortivos ósseos em pacientes odontológicos: noções de conduta para o cirurgião-dentista: uma revisão integrativa/ Bone antiresorptive drugs in dental patients: notions of conduct for dentists: an integrative review

Resin materials enriched with bioglass (45S5) could potentially improve the physicochemical properties of dental materials. Specimens were categorized into five groups: (GIC)- conventional glass ionomer cement; (RMGIC.1)- resin-modified GIC with non-lyophilised polyacrylic acid, (RMGIC.1_45S5)- RMGIC.1 with 45S5 (10 w/w%); (RMGIC.2)- resin-modified GIC with freeze-dried polyacrylic acid; and (RMGIC.2_45S5)- RMGIC.2 with 45S5 (10 w/w%). The specimens were tested at acid/neutral pH, and the antibacterial activity colony-forming units (CFU/mg), sorption, solubility, calcium ion release, and bioactivity were measured in a Streptococcus mutans biofilm model. Analysis of variance and Scheffe/Tukey statistical tests were used. The 45S5 in the RMGICs resulted in higher alkalinization and the formation of calcium/phosphorus precipitates. RMGIC.1_45S5 improved pH stability and increased the sorption and solubility. In the S.mutans biofilm, none of the materials significantly increased the pH. The enrichment of RMGIC.1 (45S5) increased the sorption, solubility, calcium release, and showed bioactivity, but had no antimicrobial effect on the S.mutans biofilm model.

A doença de Alzheimer é um tipo de demência neurodegenerativa, que afeta principalmente pacientes idosos, caracterizada pelo declínio da memória e deterioração cognitiva. Com o avanço da doença, os pacientes afetados deixam de realizar o autocuidado, incluindo os cuidados com a higiene bucal, o que favorece o surgimento de problemas de saúde bucal. Deste modo, objetivou-se analisar a produção científica acerca do assunto e descrever, através de uma revisão integrativa da literatura, a relação da doença de Alzheimer com os problemas de saúde bucal, assim como os cuidados odontológicos que o cirurgião dentista deve ter no atendimento ao paciente com a doença de Alzheimer. Foi realizada uma busca através das bases de dados PubMed®, MEDLINE® e LILACS® utilizando para a pesquisa os descritores “doença de Alzheimer”, “Saúde Oral” e “Cuidado dental”, assim como a combinação destes, sendo incluídos os artigos que tratavam da temática, publicados no período de 2016 a 2021, em português, inglês e espanhol e disponibilizados na íntegra. Nota-se uma relação entre os problemas de saúde bucal e a doença de Alzheimer, além da importância do cirurgião dentista na promoção de saúde desses pacientes, realizando um atendimento adequado de acordo com a evolução da doença e realizando a orientação de higiene bucal aos pacientes e aos seus cuidadores.