Medical Cyber-Physical Systems support the mobility of electronic health records data for clinical research to accelerate new scientific discoveries. Artificial Intelligence improves medical informatics, but current centralized data training and insecure data storage management techniques expose private medical data to unauthorized foreign entities. In this paper, a Federated Learning-based Electronic Health Record sharing scheme is proposed for Medical Informatics to preserve patient data privacy. A decentralized Federated Learning-based Convolutional Neural Network model trains data locally in the hospital and stores results in a private InterPlanetary File System. A secondary global model is trained at the research center using the local models. Private IPFS secures all medical data stored locally in the hospital. The novelty of this study resides in securing valuable hospital biomedical data useful for clinical research organizations. Blockchain and smart contracts enable patients to negotiate with external entities for rewards in exchange for their data. Evaluation results demonstrate that the decentralized CNN model performs better in accuracy, sensitivity, and specificity, similar to the traditional centralized model. The performance of the Private IPFS exceeds the Blockchain-based IPFS based on file upload and download time. The scheme is suitable for promoting a secure and privacy-friendly environment for sharing data with clinical research centers for biomedical research.

Nowadays, 5G network infrastructures are being developed for various industrial IoT (Internet of Things) applications worldwide, emerging with the IoT. As such, it is possible to deploy power-optimized technology in a way that promotes the long-term sustainability of networks. Network slicing is a fundamental technology that is implemented to handle load balancing issues within a multi-tenant network system. Separate network slices are formed to process applications having different requirements, such as low latency, high reliability, and high spectral efficiency. Modern IoT applications have dynamic needs, and various systems prioritize assorted types of network resources accordingly. In this paper, we present a new framework for the optimum performance of device applications with optimized network slice resources. Specifically, we propose a Machine Learning-based Network Sub-slicing Framework in a Sustainable 5G Environment in order to optimize network load balancing problems, where each logical slice is divided into a virtualized sub-slice of resources. Each sub-slice provides the application system with different prioritized resources as necessary. One sub-slice focuses on spectral efficiency, whereas the other focuses on providing low latency with reduced power consumption. We identify different connected device application requirements through feature selection using the Support Vector Machine (SVM) algorithm. The K-means algorithm is used to create clusters of sub-slices for the similar grouping of types of application services such as application-based, platform-based, and infrastructure-based services. Latency, load balancing, heterogeneity, and power efficiency are the four primary key considerations for the proposed framework. We evaluate and present a comparative analysis of the proposed framework, which outperforms existing studies based on experimental evaluation.

Healthcare applications store private user data on cloud servers and perform computation operations that support several patient diagnoses. Growing cyber-attacks on hospital systems result in user data being held at ransom. Furthermore, mathematical operations on data stored in the Cloud are exposed to untrusted external entities that sell private data for financial gain. In this paper, we propose a privacy-preserving scheme using homomorphic encryption to secure medical plaintext data from being accessed by attackers. Secret sharing distributes computations to several virtual nodes on the edge and masks all arithmetic operations, preventing untrusted cloud servers from learning the tasks performed on the encrypted patient data. Virtual edge nodes benefit from cloud computing resources to accomplish computing-intensive mathematical functions and reduce latency in device–edge node data transmission. A comparative analysis with existing studies demonstrates that homomorphically encrypted data stored at the edge preserves data privacy and integrity. Furthermore, secret sharing-based multi-node computation using virtual nodes ensures data confidentiality from untrusted cloud networks.

Resource constraints in the Industrial Internet of Things (IIoT) result in brute-force attacks, transforming them into a botnet to launch Distributed Denial of Service Attacks. The delayed detection of botnet formation presents challenges in controlling the spread of malicious scripts in other devices and increases the probability of a high-volume cyberattack. In this paper, we propose a secure Blockchain-enabled Digital Framework for the early detection of Bot formation in a Smart Factory environment. A Digital Twin (DT) is designed for a group of devices on the edge layer to collect device data and inspect packet headers using Deep Learning for connections with external unique IP addresses with open connections. Data are synchronized between the DT and a Packet Auditor (PA) for detecting corrupt device data transmission. Smart Contracts authenticate the DT and PA, ensuring malicious nodes do not participate in data synchronization. Botnet spread is prevented using DT certificate revocation. A comparative analysis of the proposed framework with existing studies demonstrates that the synchronization of data between the DT and PA ensures data integrity for the Botnet detection model training. Data privacy is maintained by inspecting only Packet headers, thereby not requiring the decryption of encrypted data.

Pool hopping attack is the result of miners leaving the pool when it offers fewer financial rewards and joining back when the rewards of mining yield higher rewards in blockchain networks. This act of leaving and rejoining the pool only during the good times results in the miner receiving more rewards than the computational power they contribute. Miners exiting the pool deprive it of its collective hash power, which leaves the pool unable to mine the block successfully. This results in its competitors mining the block before they can finish mining. Existing research shows pool hopping resistant measures and detection strategies; however, they do not offer any robust preventive solution to discourage miners from leaving the mining pool. To prevent pool hopping attacks, a smart contract-based pool hopping attack prevention model is proposed. The main objective of our research is maintaining the symmetrical relationship between the miners by requiring them all to continually contribute their computational power to successfully mine a block. We implement a ledger containing records of all miners, in the form of a miner certificate, which tracks the history of the miner’s earlier behavior. The certificate enables a pool manager to better initiate terms of the smart contract, which safeguards the interests of existing mining pool members. The model prevents frequent mine hoppers from pool hopping as they submit coins in the form of an escrow and risk losing them if they abandon the pool before completing mining of the block. The key critical factors that every pool hopping attack prevention solution must address and a study of comparative analysis with existing solutions are presented in the paper.