Presence of antimicrobial cocktails in the hydrological cycles is of interest because of their potential to mediate antimicrobial resistance within the natural environment. In this study, we determined the concentrations of selected antibiotics and antiretroviral drugs (ARVDs) in wastewater treatment plant (WWTP) effluent, effluent suspended particulate matter (SPM), surface waters and river sediments in Kenya in order to determine the extent of pollution within the sampled environment. Target analysis for the most common antibiotics and ARVDs was done. Sulfamethoxazole (SMX), ciprofloxacin (CIP), trimethoprim (TMP), norfloxacin (NOR), zidovidine (ZDV), lamivudine (3TC) and nevirapine (NVP) were analyzed using LC-ESI-MS/MS. Effluent aqueous phase had concentrations ranging between 1.2 µg L⁻¹ to 956.4 µg L⁻¹ while the effluent SPM showed higher concentrations, ranging between 2.19 mg Kg⁻¹ and 82.26 mg Kg⁻¹. This study shows emission of active pharmaceutical ingredients (APIs) from WWTP to the environment mainly occurs via the SPM phase, which is usually overlooked in environmental analyses. Concentrations in surface waters and river sediments ranged between 1.1 µg L⁻¹ to 228 µg L⁻¹ and 11 µg Kg⁻¹ to 4125 µg Kg⁻¹ respectively. ARVDs occurred at consistently higher concentrations than antibiotics in both the aqueous and solid samples. The wastewater treatment plants and lagoons where sludge degradation should occur, are sources of active pharmaceutical ingredients (APIs) including transformational products, nutrients and organic matter that are released back to the aqueous phase.

Antibiotic residues are of significant concern in the ecosystem because of their capacity to mediate antibiotic resistance development among environmental microbes. This paper reviews recent technologies for the abatement of antibiotics from human urine and wastewaters. Antibiotics are widely distributed in the aquatic environment as a result of the discharge of municipal sewage. Their existence is a cause for worry due to the potential ecological impact (for instance, antibiotic resistance) on bacteria in the background. Numerous contaminants that enter wastewater treatment facilities and the aquatic environment, as a result, go undetected. Sludge can act as a medium for some chemicals to concentrate while being treated as wastewater. The most sewage sludge that has undergone treatment is spread on agricultural land without being properly checked for pollutants. The fate of antibiotic residues in soils is hence poorly understood. The idea of the Separation of urine at the source has recently been propagated as a measure to control the flow of pharmaceutical residues into centralized wastewater treatment plants (WWTPs). With the ever increasing acceptance of urine source separation practices, visibility and awareness on dedicated treatement technologies is needed. Human urine, as well as conventional WWTPs, are point sources of pharmaceutical micropollutants contributing to the ubiquitous detection of pharmaceutical residues in the receiving water bodies. Focused post-treatment of source-separated urine includes distillation and nitrification, ammonia stripping, and adsorption processes. Other reviewed methods include physical and biological treatment methods, advanced oxidation processes, and a host of combination treatment methods. All these are aimed at ensuring minimized risk products are returned to the environment.

Cellulose is an inexpensive, renewable, bio-based and an abundant raw material suitable for the development of filter membranes for water purification. This is because it has numerous functional groups that afford ease of modification to create active surfaces upon chemical modification. In this study, cellulose was isolated from two abundant biomasses, namely, Eichhornia crassipes and Cyperus papyrus using the soda process followed by bleaching with peracetic acid. The percent yield of cellulose nanofibrils (CNF) obtained from E. crassipes and C. papyrus was found to be 31.64 ± 1.46% and 29.55 ± 0.64% respectively. The degree of crystallinity and crystal sizes were calculated to be 71.42% and 0.059 nm for E. crassipes and 46.15% and 0.068 nm for C. papyrus respectively. The FT-IR absorption of the carbonyl functional group of an ester indicated that effective esterification of cellulose using citric acid was obtained when cellulose nanofibrils to citric acid ratio was 1:1. From batch adsorption studies, the capacity for citric acid modified cellulose to remove heavy metals was determined to be 8.36 mg/g Zn²⁺, 18.06 mg/g Cu²⁺, 42.69 mg/g Cd²⁺ and 21.64 mg/g Pb²⁺. In comparison to the % adsorption using unmodified cellulose of less than 5%, the heavy metals adsorption using modified nanocellulose materials were 86.47% Pb²⁺, 85.20% Cd²⁺, 77.40% Cu²⁺, and 70.04% Zn²⁺. From these results, it was concluded that modified cellulose could be used as a low cost adsorbent for removal of heavy metals and that development of household water filtration units using modified cellulose could be exploited.