Joanna Wezgowiec

Dr. Joanna Wezgowiec

Wroclaw Medical University, Faculty of Dentistry, Department of Experimental Dentistry
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Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 June 2017
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Julita KulbackaJulita Kulbacka
Julita Kulbacka
ACAnna Choromańska
Anna Choromańska
JRJoanna Rossowska
Joanna Rossowska
JWJoanna Wezgowiec
Joanna Wezgowiec
JSJolanta Saczko
Jolanta Saczko
Marie-Pierre RolsMarie-Pierre Rols
Marie-Pierre Rols

Verified
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Anna Paradowska-StolarzAnna Paradowska-Stolarz
Anna Paradowska-Stolarz
Mieszko WieckiewiczMieszko Wieckiewicz
Mieszko Wieckiewicz
AOArtur Owczarek
Artur Owczarek
JWJoanna Wezgowiec
Joanna Wezgowiec
The success of modern dental treatment is strongly dependent on the materials used both temporarily and permanently. Among all dental materials, polymers are a very important class with a wide spectrum of applications. This review aims to provide a state-of-the-art overview of the recent advances in the field of natural polymers used to maintain or restore oral health. It focuses on the properties of the most common proteins and polysaccharides of natural origin in terms of meeting the specific biological requirements in the increasingly demanding field of modern dentistry. The use of naturally derived polymers in different dental specialties for preventive and therapeutic purposes has been discussed. The major fields of application cover caries and the management of periodontal diseases, the fabrication of membranes and scaffolds for the regeneration of dental structures, the manufacturing of oral appliances and dentures as well as providing systems for oral drug delivery. This paper also includes a comparative characteristic of natural and synthetic dental polymers. Finally, the current review highlights new perspectives, possible future advancements, as well as challenges that may be encountered by researchers in the field of dental applications of polymers of natural origin.

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AMAndrzej Malysa
Andrzej Malysa
JWJoanna Wezgowiec
Joanna Wezgowiec
WGWojciech Grzebieluch
Wojciech Grzebieluch
DDDariusz Danel
Dariusz Danel
Mieszko WieckiewiczMieszko Wieckiewicz
Mieszko Wieckiewicz
The aim of the study was to evaluate the influence of thermocycling on the shear bond strength of self-adhesive, self-etching resin cements luted to human dentin and computer-aided design/computer-aided manufacturing (CAD/CAM) ceramics. Three modern self-adhesive dental cements (Maxcem Elite, RelyX U200, Panavia SA) were used to lute three CAD/CAM ceramics (IPS Empress CAD, IPS e.max CAD, IPS e.max ZirCAD) onto the dentin. One conventional cement (Panavia V5) served as a control. After preparation, the samples were subjected to thermocycling as a method of artificial aging of dental materials applied to simulate long-term use in oral conditions. Shear bond strength was evaluated according to PN-EN ISO 29022:2013-10 and failure modes were observed under a light microscope. Statistical analysis was performed. The study demonstrated that a combination of ceramics and cements directly impacts the bond strength. The highest bond strength was observed in Panavia V5, lower in Panavia SA and Maxcem Elite and the lowest–in RelyX U200. Adhesive failure between human dentin and cements was the most common failure mode. Moreover, thermocycling highly decreased bond strength of self-adhesive, self-etching cements.

22 May 2020 in Molecules
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JWJoanna Wezgowiec
Joanna Wezgowiec
AWAnna Wieczynska
Anna Wieczynska
WWWlodzimierz Wieckiewicz
Wlodzimierz Wieckiewicz
Julita KulbackaJulita Kulbacka
Julita Kulbacka
JSJolanta Saczko
Jolanta Saczko
KWKazimiera A. Wilk
Kazimiera A. Wilk
The purpose of this study was to compare the chemical composition and biological properties of Polish propolis. Ethanol, ethanol-hexane, hexane and hexane-ethanol extracts of propolis from three different regions of Poland were prepared. On the basis of the evaluation of their chemical composition as well as the extraction yield and free radical scavenging activity, the ethanol and hexane-ethanol extractions were proposed as the most effective methods. Subsequently, the biological properties of the extracts were evaluated to investigate the selectivity of an anticancer effect on tongue cancer cells in comparison to normal gingival fibroblasts. The obtained products demonstrated anticancer activity against tongue cancer cells. Additionally, when the lowest extract concentration (100 µg/mL) was applied, they were not cytotoxic to gingival fibroblasts. Finally, a possible anti-inflammatory potential of the prepared products was revealed, as reduced mitochondrial activity and proliferation of macrophages exposed to the extracts were observed. The results obtained indicate a potential of Polish propolis as a natural product with cancer-selective toxicity and anti-inflammatory effect. However, further studies are still needed to thoroughly explain the molecular mechanisms of its action and to obtain the promising health benefits of this versatile natural product.

Verified
Journal Article
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JWJoanna Wezgowiec
Joanna Wezgowiec
Anna Paradowska-StolarzAnna Paradowska-Stolarz
Anna Paradowska-Stolarz
AMAndrzej Malysa
Andrzej Malysa
SOSylwia Orzeszek
Sylwia Orzeszek
PSPiotr Seweryn
Piotr Seweryn
Mieszko WieckiewiczMieszko Wieckiewicz
Mieszko Wieckiewicz
There is an ongoing search for novel disinfection techniques that are not only effective, cheap, and convenient, but that also do not have adverse effects on the properties of dental impressions. We compared the effects of various methods (UVC, gaseous ozone, commercial solution, and spray) on the dimensional change, tensile strength, and hardness of silicone impressions. Moreover, as a secondary aim, we performed a statistical comparison of the properties of nondisinfected addition (Panasil Putty Soft, Panasil monophase Medium, Panasil initial contact Light) and condensation silicones (Zetaplus Putty and Oranwash L), as well as a comparison of materials of various viscosities (putty, medium-bodied, and light-bodied). Our results revealed that addition silicones had higher dimensional stability, tensile strength, and Shore A hardness compared to condensation silicones. Both traditional (immersion and spraying) and alternative methods of disinfection (UVC and ozone) had no significant impact on the tensile properties and dimensional stability of the studied silicones; however, they significantly affected the hardness, particularly of Oranwash L. Our study demonstrated that, similarly to standard liquid disinfectants, both UVC and ozone do not strongly affect the material properties of most silicones. However, before recommendation, their usefulness for each individual material should be thoroughly evaluated.

25 February 2021 in Molecules
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Journal Article
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AMAndrzej Malysa
Andrzej Malysa
JWJoanna Wezgowiec
Joanna Wezgowiec
SOSylwia Orzeszek
Sylwia Orzeszek
WFWojciech Florjanski
Wojciech Florjanski
MZMarek Zietek
Marek Zietek
Mieszko WieckiewiczMieszko Wieckiewicz
Mieszko Wieckiewicz
For long-term successful use of ceramic materials in dental procedures, it is necessary to ensure reliable bonding of restorations to dental substrates. This can be achieved by the application of a proper luting cement and through additional surface conditioning. The present systematic review summarizes the most up-to-date evidence on the use of different surface modification methods to enhance the bond strength of dental ceramics to the hard tissues of the teeth. The authors of the review searched the Web of Science, Scopus, and MEDLINE databases to identify relevant articles published between 1 January 2010 and 1 January 2020. A total of 4892 records were identified, and after screening, the full text of 159 articles was evaluated, which finally resulted in the inclusion of 19 studies. The available reports were found to be heterogeneous in terms of materials and methodology, and therefore, only within-studies comparison was performed instead of comparison between studies. A statistically significant difference in the bond strength between the samples treated with different methods of surface conditioning, or between conditioned and nonconditioned samples, was revealed by most of the studies. Predominantly, the studies showed that a combination of mechanical and chemical methods was the most effective way of enhancing bond strength. Artificial aging and luting cement were also identified as the factors significantly influencing bond strength.