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Papaya fruits (Carica papaya L.) are valuable both as food, including concentrates and mixed beverages and in traditional medicine. The goal of the study was to evaluate the antioxidant activity of various parts of unripe and ripe papaya fruit from the DPPH· kinetics point of view. Peel, pulp, seed, and seed-pulp of unripe and ripe papaya fruits (¼ and >¾ level of ripening) were extracted with ethanol and monitored at 517 nm in the presence of DPPH·. The radical scavenging capacity (RSC) at various time ranges and DPPH· reaction rates for specific time intervals were determined. The highest RSC values were obtained for papaya pulp extracts, consistently higher for the ripe samples in comparison with the unripe ones (86.4% and 41.3%). The DPPH· rates significantly differ for the unripe and ripe papaya extracts, especially for the first time range. They are more than double for the ripe papaya. These values were 2.70, 4.00, 3.25, 2.75 μM/s for the peel, pulp, seed, seed-pulp extracts from the ripe papaya and only 1.00, 1.65, 1.40, 1.80 μM/s for the unripe samples. DPPH· kinetic approach can be useful for a fast and simple evaluation of the overall antioxidant properties of fruit extracts.
Olimpia Alina Iordănescu; Maria Băla; Dina Gligor (Pane); Simelda Elena Zippenfening; Marius Ioan Cugerean; Mircea Ionuţ Petroman; Daniel Ioan Hădărugă; Nicoleta Gabriela Hădărugă; Mircea Riviş. A DPPH· Kinetic Approach on the Antioxidant Activity of Various Parts and Ripening Levels of Papaya (Carica papaya L.) Ethanolic Extracts. Plants 2021, 10, 1679 .
AMA StyleOlimpia Alina Iordănescu, Maria Băla, Dina Gligor (Pane), Simelda Elena Zippenfening, Marius Ioan Cugerean, Mircea Ionuţ Petroman, Daniel Ioan Hădărugă, Nicoleta Gabriela Hădărugă, Mircea Riviş. A DPPH· Kinetic Approach on the Antioxidant Activity of Various Parts and Ripening Levels of Papaya (Carica papaya L.) Ethanolic Extracts. Plants. 2021; 10 (8):1679.
Chicago/Turabian StyleOlimpia Alina Iordănescu; Maria Băla; Dina Gligor (Pane); Simelda Elena Zippenfening; Marius Ioan Cugerean; Mircea Ionuţ Petroman; Daniel Ioan Hădărugă; Nicoleta Gabriela Hădărugă; Mircea Riviş. 2021. "A DPPH· Kinetic Approach on the Antioxidant Activity of Various Parts and Ripening Levels of Papaya (Carica papaya L.) Ethanolic Extracts." Plants 10, no. 8: 1679.
Background: Oral cancer is a worldwide public health problem, being the sixth most common neoplasm. The high mortality rate of this type of cancer is due to a delayed diagnosis, a fast evolution and metastasis, no primary symptomatology, the multitude of risk factors and the lack of awareness among the population concerning oral malignancy. Aim: The aim of this 5-year retrospective study was to evaluate the incidence of oral cancer patients in the Clinic of Maxillo-Facial Surgery, Emergency County Hospital, Timişoara, Romania and quantify the histopathological (HP) subtypes, localization, age, gender, tumor staging and differentiation, positive loco-regional lymph nodes and risk factors. Patients, Materials and Methods: A number of 129 patients diagnosed with oral cancer were included in the study and their medical records were analyzed. A statistical analysis was performed that included the variables gender, age, tumor staging, differentiation grade, HP subtype, lymph nodes, localization, and risk factors. Results: Our results outlined a high prevalence of oral cancer among males (65.9%), squamous cell carcinoma (SCC) being the most common HP subtype. Tumor staging revealed the fact that the majority of were T3 and T4 tumors with dissemination in the loco-regional lymph nodes. In 52% of the cases, tobacco was identified as a risk factor, and the association of tobacco and alcohol was present in 28.3% of the cases. Conclusions: The early diagnosis is crucial for the improvement of oral cancer survival rate. The oral cavity is permanently exposed to carcinogenic substances that associated with other risk factors have an influence upon the incidence of oral malignancies.
Alexandra Roi; Ciprian Ioan Roi; Nicoleta Ioana Andreescu; Mircea Riviş; Ioana Daniela Badea; Noemi Meszaros; Laura Cristina Rusu; Stela Iurciuc. Oral cancer histopathological subtypes in association with risk factors: a 5-year retrospective study. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2021, 61, 1213 -1220.
AMA StyleAlexandra Roi, Ciprian Ioan Roi, Nicoleta Ioana Andreescu, Mircea Riviş, Ioana Daniela Badea, Noemi Meszaros, Laura Cristina Rusu, Stela Iurciuc. Oral cancer histopathological subtypes in association with risk factors: a 5-year retrospective study. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. 2021; 61 (4):1213-1220.
Chicago/Turabian StyleAlexandra Roi; Ciprian Ioan Roi; Nicoleta Ioana Andreescu; Mircea Riviş; Ioana Daniela Badea; Noemi Meszaros; Laura Cristina Rusu; Stela Iurciuc. 2021. "Oral cancer histopathological subtypes in association with risk factors: a 5-year retrospective study." Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 61, no. 4: 1213-1220.
The goal of the study was to evaluate the influence of the solvent properties on the crystal characteristics of β-cyclodextrin (β-CD) recrystallized from alcohol-water solvent mixtures, with possible applications for the preparation, purifying and complexation of β-CD. For the first time, structure-property relationships (QSPRs) between the hydrophobicity of alcohols or dielectric constant of solvents used for recrystallization of β-CD and its properties (such as crystallinity index, CI) have been obtained. Recrystallized β-CD from water and C1-C4 alcohol-water solutions provide β-CD with higher CI values of 99.4(±5.9)% for ethanol-water (1:4, v/v) as recrystallizing system. This property has a parabolic variation with the logP (octanol/water partition coefficient) of the alcohol (r2 = 0.998). Solvent parameters also influence the β-CD crystal characteristics, as was demonstrated by X-ray diffractometry refinement, infrared spectroscopy and thermal analyses.
Mihai A. Medeleanu; Daniel I. Hădărugă; Cornelia V. Muntean; Gabriela Popescu; Maria Rada; Alina Hegheş; Simelda E. Zippenfening; Christine A. Lucan (Banciu); Ariana B. Velciov; Geza N. Bandur; Nicoleta G. Hădărugă; Mircea Riviş. Structure-property relationships on recrystallized β-cyclodextrin solvates: A focus on X-ray diffractometry, FTIR and thermal analyses. Carbohydrate Polymers 2021, 265, 118079 .
AMA StyleMihai A. Medeleanu, Daniel I. Hădărugă, Cornelia V. Muntean, Gabriela Popescu, Maria Rada, Alina Hegheş, Simelda E. Zippenfening, Christine A. Lucan (Banciu), Ariana B. Velciov, Geza N. Bandur, Nicoleta G. Hădărugă, Mircea Riviş. Structure-property relationships on recrystallized β-cyclodextrin solvates: A focus on X-ray diffractometry, FTIR and thermal analyses. Carbohydrate Polymers. 2021; 265 ():118079.
Chicago/Turabian StyleMihai A. Medeleanu; Daniel I. Hădărugă; Cornelia V. Muntean; Gabriela Popescu; Maria Rada; Alina Hegheş; Simelda E. Zippenfening; Christine A. Lucan (Banciu); Ariana B. Velciov; Geza N. Bandur; Nicoleta G. Hădărugă; Mircea Riviş. 2021. "Structure-property relationships on recrystallized β-cyclodextrin solvates: A focus on X-ray diffractometry, FTIR and thermal analyses." Carbohydrate Polymers 265, no. : 118079.
Background and Objectives: Antiresorptive or anti-angiogenic agents may induce medication-related osteonecrosis of the jaws (MRONJ), which represents a challenge for clinicians. The aim of this study is to design and apply a composed and stage-approach therapy combining antibiotherapy, surgical treatment, and photo-biomodulation (PBM) for the prevention or treatment of MRONJ lesions. Materials and Methods: The proposed treatment protocol was carried out in the Department of Oral & Maxillofacial Surgery of the “Victor Babes” University of Medicine and Farmacy of Timisoara, in 2018–2020. A total of 241 patients who were previously exposed to antiresorptive or anti-angiogenic therapy, as well as patients already diagnosed with MRONJ at different stages of the disease were treated. A preventive protocol was applied for patients in an “at risk” stage. Patients in more advanced stages received a complex treatment. Results: The healing proved to be complete, with spontaneous bone coverage in all the n = 84 cases placed in an “at risk” stage. For the n = 49 patients belonging to stage 0, pain reductions and decreases of mucosal inflammations were also obtained in all cases. For the n = 108 patients proposed for surgery (i.e., in stages 1, 2, or 3 of MRONJ), a total healing rate of 91.66% was obtained after the first surgery, while considering the downscaling to stage 1 as a treatment “success”, only one “failure” was reported. This brings the overall “success” rate to 96.68% for a complete healing, and to 99.59% when downscaling to stage 1 is included in the healing rate. Conclusions: Therefore, the clinical outcome of the present study indicates that patients with MRONJ in almost all stages of the disease can benefit from such a proposed association of methods, with superior clinical results compared to classical therapies.
Diana Nica; Mircea Riviș; Ciprian Roi; Carmen Todea; Virgil-Florin Duma; Cosmin Sinescu. Complementarity of Photo-Biomodulation, Surgical Treatment, and Antibiotherapy for Medication-Related Osteonecrosis of the Jaws (MRONJ). Medicina 2021, 57, 145 .
AMA StyleDiana Nica, Mircea Riviș, Ciprian Roi, Carmen Todea, Virgil-Florin Duma, Cosmin Sinescu. Complementarity of Photo-Biomodulation, Surgical Treatment, and Antibiotherapy for Medication-Related Osteonecrosis of the Jaws (MRONJ). Medicina. 2021; 57 (2):145.
Chicago/Turabian StyleDiana Nica; Mircea Riviș; Ciprian Roi; Carmen Todea; Virgil-Florin Duma; Cosmin Sinescu. 2021. "Complementarity of Photo-Biomodulation, Surgical Treatment, and Antibiotherapy for Medication-Related Osteonecrosis of the Jaws (MRONJ)." Medicina 57, no. 2: 145.
(1) Background: Oronasal communication is described in the scientific literature as a common complication that occurs after a cleft palate surgery. In some cases, it can also be a consequence of oral surgery procedures; the main problem of this type of rare accident is related to the correct healing process and treatment option. (2) Case report: A patient with oronasal communication caused by an unsuccessful attempt of a superior canine odontectomy presented at the Emergency Department of the Oral and Maxillofacial Surgery Hospital, Timișoara. The case management is described from the first consult to one-year follow-up. We consider that this pathology was optimally treated surgically, and the results are more than satisfactory, taking into consideration the high rates of recurrence. (3) Conclusion: This case report can be a useful to a general dentist who is trying to decide whether to perform the canine odontectomy or refer to a specialist surgeon due to the accidents and complications of this procedure.
Ciprian Roi; Emilia Ianeș; Diana Nica; Alexandra Roi; Laura Cristina Rusu; Ioana Badea; Mircea Riviș. Rare Iatrogenic Oronasal Communication after Superior Canine Odontectomy Attempt. Timisoara Medical Journal 2021, 2020, 1 .
AMA StyleCiprian Roi, Emilia Ianeș, Diana Nica, Alexandra Roi, Laura Cristina Rusu, Ioana Badea, Mircea Riviș. Rare Iatrogenic Oronasal Communication after Superior Canine Odontectomy Attempt. Timisoara Medical Journal. 2021; 2020 (2):1.
Chicago/Turabian StyleCiprian Roi; Emilia Ianeș; Diana Nica; Alexandra Roi; Laura Cristina Rusu; Ioana Badea; Mircea Riviș. 2021. "Rare Iatrogenic Oronasal Communication after Superior Canine Odontectomy Attempt." Timisoara Medical Journal 2020, no. 2: 1.
(1) Background: The water content and the way of bonding in the food matrices, including bread, can be easily and simply evaluated by Karl Fischer titration (KFT). The goal was to identify the main KFT parameters that influence the similarity/dissimilarity of commercial bread products, using multivariate statistical analysis. (2) Methods: Various commercial bread samples were analyzed by volumetric KFT and the water content, parameters from titration process and KFT kinetics were used as input for principal component analysis (PCA). (3) Results: The KFT water content was in the range of 35.1–44.2% for core samples and 19.4–22.9% for shell samples. The storage and transportation conditions consistently influence the water content of bread. The type of water molecules can be evaluated by means of KFT water reaction rates. The mean water reaction rates up to 2 min are consistently higher for bread core samples, which indicates a high fraction of “surface” water. PCA reveals the similarity of core samples and various bread types, as well as dissimilarity between bread parts, mainly based on KFT kinetic parameters. (4) Conclusions: KFT kinetics can be a useful tool for a rapid and simple differentiations between various types of bread products.
Gabriela Popescu; Isidora Radulov; Olimpia A. Iordănescu; Manuela D. Orboi; Laura Rădulescu; Mărioara Drugă; Gabriel S. Bujancă; Ioan David; Daniel I. Hădărugă; Christine A. Lucan (Banciu); Nicoleta G. Hădărugă; Mircea Riviş. Karl Fischer Water Titration—Principal Component Analysis Approach on Bread Products. Applied Sciences 2020, 10, 6518 .
AMA StyleGabriela Popescu, Isidora Radulov, Olimpia A. Iordănescu, Manuela D. Orboi, Laura Rădulescu, Mărioara Drugă, Gabriel S. Bujancă, Ioan David, Daniel I. Hădărugă, Christine A. Lucan (Banciu), Nicoleta G. Hădărugă, Mircea Riviş. Karl Fischer Water Titration—Principal Component Analysis Approach on Bread Products. Applied Sciences. 2020; 10 (18):6518.
Chicago/Turabian StyleGabriela Popescu; Isidora Radulov; Olimpia A. Iordănescu; Manuela D. Orboi; Laura Rădulescu; Mărioara Drugă; Gabriel S. Bujancă; Ioan David; Daniel I. Hădărugă; Christine A. Lucan (Banciu); Nicoleta G. Hădărugă; Mircea Riviş. 2020. "Karl Fischer Water Titration—Principal Component Analysis Approach on Bread Products." Applied Sciences 10, no. 18: 6518.
Fast, economic, and noninvasive, molecular analysis of saliva has the potential to become a diagnostic tool of reference for several local and systemic diseases, oral cancer included. The diagnosis of Oral Squamous Cell Carcinoma (OSCC) can be performed using high specificity and sensibility biomarkers that can be encountered in the biological fluids. Recent advances in salivary proteomics have underlined the potential use of salivary biomarkers as early diagnosis screening tools for oral neoplasia. In this respect, over 100 salivary molecules have been described and proposed as oral cancer biomarkers, out of which cytokines are among the most promising. Besides being directly involved in inflammation and immune response, the role of salivary cytokines in tumor growth and progression linked them to the incidence of oral malignant lesions. This review summarizes the existing studies based on the use of salivary cytokines as potential oral cancer biomarkers, their involvement in the malignant process based on their type, and ther influence upon prognostic and metastatic rates.
Alexandra Roi; Ciprian Ioan Roi; Meda Lavinia Negruțiu; Mircea Riviș; Cosmin Sinescu; Laura-Cristina Rusu. The Challenges of OSCC Diagnosis: Salivary Cytokines as Potential Biomarkers. Journal of Clinical Medicine 2020, 9, 2866 .
AMA StyleAlexandra Roi, Ciprian Ioan Roi, Meda Lavinia Negruțiu, Mircea Riviș, Cosmin Sinescu, Laura-Cristina Rusu. The Challenges of OSCC Diagnosis: Salivary Cytokines as Potential Biomarkers. Journal of Clinical Medicine. 2020; 9 (9):2866.
Chicago/Turabian StyleAlexandra Roi; Ciprian Ioan Roi; Meda Lavinia Negruțiu; Mircea Riviș; Cosmin Sinescu; Laura-Cristina Rusu. 2020. "The Challenges of OSCC Diagnosis: Salivary Cytokines as Potential Biomarkers." Journal of Clinical Medicine 9, no. 9: 2866.
Titanium alloys are known for their biological, mechanical and chemical properties, which have successfully expanded their use in the maxillofacial field. The internal fixation using titanium miniplates and screws offer a new perspective for the treatment of trauma and in orthognathic surgery and maxillofacial oncology. Although, titanium is highly recommended for its excellent biocompatibility, recent research has focused on identifying the potential local and general implications of the interactions between the human tissue and the metallic particles. This present review aims to outline the existing tissue changes, cellular alterations and future perspectives regarding the use of titanium-based alloys as osteosynthesis materials, taking into consideration the existing present debate whether the routinely removal of these materials should be an indication.
Mircea Riviș; Ciprian Roi; Alexandra Roi; Diana Nica; Adina Văleanu; Laura-Cristina Rusu. The Implications of Titanium Alloys Applied in Maxillofacial Osteosynthesis. Applied Sciences 2020, 10, 3203 .
AMA StyleMircea Riviș, Ciprian Roi, Alexandra Roi, Diana Nica, Adina Văleanu, Laura-Cristina Rusu. The Implications of Titanium Alloys Applied in Maxillofacial Osteosynthesis. Applied Sciences. 2020; 10 (9):3203.
Chicago/Turabian StyleMircea Riviș; Ciprian Roi; Alexandra Roi; Diana Nica; Adina Văleanu; Laura-Cristina Rusu. 2020. "The Implications of Titanium Alloys Applied in Maxillofacial Osteosynthesis." Applied Sciences 10, no. 9: 3203.
M Riviş; Adina Nora Văleanu. Giant maxillary cyst with intrasinusal evolution. Romanian Journal of Morphology and Embryology 2013, 54, 1 .
AMA StyleM Riviş, Adina Nora Văleanu. Giant maxillary cyst with intrasinusal evolution. Romanian Journal of Morphology and Embryology. 2013; 54 (3):1.
Chicago/Turabian StyleM Riviş; Adina Nora Văleanu. 2013. "Giant maxillary cyst with intrasinusal evolution." Romanian Journal of Morphology and Embryology 54, no. 3: 1.
A.N. Valeanu; L.E. Vasile; M. Riviş. P.273 The significance of the morphological indicators for the diagnosis of the cysts of the jaws. Journal of Cranio-Maxillofacial Surgery 2006, 34, 202 .
AMA StyleA.N. Valeanu, L.E. Vasile, M. Riviş. P.273 The significance of the morphological indicators for the diagnosis of the cysts of the jaws. Journal of Cranio-Maxillofacial Surgery. 2006; 34 ():202.
Chicago/Turabian StyleA.N. Valeanu; L.E. Vasile; M. Riviş. 2006. "P.273 The significance of the morphological indicators for the diagnosis of the cysts of the jaws." Journal of Cranio-Maxillofacial Surgery 34, no. : 202.