Staphylococcus aureusis recognized as commensal as well as opportunistic pathogen of humans and animals. Methicillin resistant strain ofS. aureus(MRSA) has emerged as a major pathogen in hospitals, community and veterinary settings that compromises the public health and livestock production. MRSA basically emerged from MSSA after acquiring SCCmecelement through gene transfer containingmecA generesponsible for encoding PBP-2α. This protein renders the MRSA resistant to most of the β-lactam antibiotics. Due to the continuous increasing prevalence and transmission of MRSA in hospitals, community and veterinary settings posing a major threat to public health. Furthermore, high pathogenicity of MRSA due to a number of virulence factors produced byS. aureusalong with antibiotic resistance help to breach the immunity of host and responsible for causing severe infections in humans and animals. The clinical manifestations of MRSA consist of skin and soft tissues infection to bacteremia, septicemia, toxic shock, and scalded skin syndrome. Moreover, due to the increasing resistance of MRSA to number of antibiotics, there is need to approach alternatives ways to overcome economic as well as human losses. This review is going to discuss various aspects of MRSA starting from emergence, transmission, epidemiology, pathophysiology, disease patterns in hosts, novel treatment, and control strategies.

Livestock is an integral part of agriculture countries where ticks play significant role as potent pests causing considerable losses to economy and health. Drug resistance has made these pests supersede conventional therapies and control programs Nanotechnology here comes as an advancing and significant candidate alternatively able to reverse drug resistance. Nanoparticles, hence, against ticks may better be considered as nanopesticides that act in ways other than conventional drug efficacies. The methods of nanoparticles production include green synthesis, chemical synthesis, and arthropod‐based synthesis. Pros and cons of these nanopesticides are by no means neglectable. Studies are fewer than needed to comprehensively discuss nanopesticides. Current review thus systematically covers aspects of ticks as livestock pests, their drug resistance, advent of nanotechnology against pests, their production methodologies, mechanisms of actions of ticks, and current limitations. This review opens several avenues for further research on nanoparticles as nanopesticides against ticks.