Smart electronic materials ‘nanographene’ stated, its significant authentication has undergone massive improvements and has emerged as a ‘material of the century’ in materialize fields of ‘Chemical Biology’ and ‘Materials Chemistry’. ‘Graphene’ as a wonder material has been proposed to possess a high surface area (∼2600 m² g⁻¹), high portability of charge carriers and excellent mechanical qualities. Moreover, the long-extend π-conjugation of graphene is an essential photocatalytic property enabling wide ranging biosensor activities. Herein, critical review article reflects well known yet a brand-new novel material ‘nanographene’ and its versatile integrations, utilized for substantial enrichment of desired properties. Target cost-effectiveness, plasticity, and environment-friendliness of melt mixing/compounding fabrication strategy employed to utilize in-vivo, in-vitro, and in- situ, pharmaceutical, nano-imaging protocols. Owing to nanographene’s wide range expansion, summarized latest breakthroughs in Materials Science as well as Biomedical utilizations including cancer nanotechnology, drug delivery, tissue manufacturing, scaffold, photo-thermal therapy, antimicrobial activities, made up of exploring the significant opportunities and key challenges in this novel emerging field.

Macrocyclic lactones, particularly the avermectins, have completely revolutionized the approaches aimed at control of parasites. These avermectins are the most widely used anti-parasitic drugs in veterinary field with sales exceeding one billion US dollars annually. However, before clinical usage, their safety evaluation in the animals is a major critical factor that must be considered. Many studies have reported the negative effects of avermectins like ivermectin, abamectin, doramectin, and eprinomectin on the host animals. These harmful effects arise from avermectins targeting GABA and glutamate-gated chloride channels present both in the parasites and the host animals. In this review, various modes of avermectins action along with the negative effects on the host like nephrotoxicity, hepatotoxicity, neurotoxicity, reproductive toxicity, and endocrine disruption were discussed in detail. Furthermore, other important issues like ecotoxicity, drug resistance, and drug residues in milk associated with avermectins usage were also discussed, which need special attention.

Nanoscale size-dependent properties give nanomaterials unique specifications that are robust in many applications of human medicine. Gold nanoparticles (AuNPs) have recently gained attention becaus... Graphical abstract

Livestock is an integral part of agriculture countries where ticks play significant role as potent pests causing considerable losses to economy and health. Drug resistance has made these pests supersede conventional therapies and control programs Nanotechnology here comes as an advancing and significant candidate alternatively able to reverse drug resistance. Nanoparticles, hence, against ticks may better be considered as nanopesticides that act in ways other than conventional drug efficacies. The methods of nanoparticles production include green synthesis, chemical synthesis, and arthropod‐based synthesis. Pros and cons of these nanopesticides are by no means neglectable. Studies are fewer than needed to comprehensively discuss nanopesticides. Current review thus systematically covers aspects of ticks as livestock pests, their drug resistance, advent of nanotechnology against pests, their production methodologies, mechanisms of actions of ticks, and current limitations. This review opens several avenues for further research on nanoparticles as nanopesticides against ticks.