Claudia Zadra

Prof. Claudia Zadra


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
19 May 2023 in Molecules
Verified
Journal Article
Open access
PDF file
Samir ScandarSamir Scandar
Samir Scandar
CZClaudia Zadra
Claudia Zadra
Maria Carla MarcotullioMaria Carla Marcotullio
Maria Carla Marcotullio
Coriander is a widely used plant for its medicinal and biological properties. Both coriander essential oil and extracts are interesting sources of bioactive compounds and are widely used as spices in culinary practice due to their exclusive aroma and flavour. We focus our attention on coriander extracts that are rich in polyphenols. It is well known that plant polyphenols possess different biological activities and several functional foods contain this class of compounds. The polyphenol profile in an extract can be influenced by the plant part studied, the method of extraction and other parameters. This study performs a literature review using the words “coriander”, “polyphenols” and “extraction” or “biological activity” in different databases such as PubMed, Google Scholar and Scopus. After that, we focus on the evidence of coriander polyphenols as protective agents against some inflammation-related diseases. Due to the bioactivities of coriander extract, this herb can be considered a valuable functional food against obesity, metabolic syndrome and diabetes.

6 August 2024 in Biomass
Verified
Journal Article
Open access
PDF file
JMJessica Di mario
Jessica Di mario
Nicolò MontegioveNicolò Montegiove
Nicolò Montegiove
AGAlberto Maria Gambelli
Alberto Maria Gambelli
Monica BrienzaMonica Brienza
Monica Brienza
CZClaudia Zadra
Claudia Zadra
Giovanni GigliottiGiovanni Gigliotti
Giovanni Gigliotti
Second- and third-generation biorefineries enable the sustainable management of biomasses within the framework of circular economy principles. This approach aims to minimize waste biomass while generating high-value molecules and bio-energy, such as biogas. Biogas production is achieved via anaerobic digestion, a process where microorganisms metabolize organic compounds in the absence of oxygen to primarily produce CO2 and CH4. The efficiency of this process is closely linked to the composition of the biomass and, sometimes, characteristics of the initial matrix can impede the process. To address these challenges, various pretreatments are employed to enhance digestion efficiency and mitigate issues associated with biomass complexity. However, the implementation of pretreatments can be energy-intensive and costly. The extraction of valuable molecules from biomass for various applications can represent a form of pretreatment. This extraction process selectively removes recalcitrant molecules such as lignin and cellulose, which can hinder biodegradation, thereby adding new value to the biomass. These extracted molecules not only contribute to improved anaerobic digestion efficiency but also offer potential economic benefits by serving as valuable inputs across diverse industrial sectors. This article presents a detailed state of the art of the most widespread biomass pretreatments and specifies when biomass is pretreated to improve the biogas yield and, in contrast, when it is treated to extract high-added-value products. Finally, in order to define if the same treatment can be simultaneously applied for both goals, an experimental section was dedicated to the production of biogas from untreated olive mill wastewater and the same biomass after being freeze-dried and after the extraction of polyphenols and flavonoids. The use of pretreated biomass effectively improved the biogas production yield: the untreated olive mill wastewater led to the production of 147 mL of biogas, while after freeze-drying and after polyphenols/flavonoids extraction, the production was, respectively, equal to 169 mL and 268 mL of biogas.

4 March 2024 in Agronomy
Verified
Journal Article
Open access
PDF file
Nicolò MontegioveNicolò Montegiove
Nicolò Montegiove
AGAlberto Maria Gambelli
Alberto Maria Gambelli
ECEleonora Calzoni
Eleonora Calzoni
ABAgnese Bertoldi
Agnese Bertoldi
Debora PugliaDebora Puglia
Debora Puglia
Giovanni GigliottiGiovanni Gigliotti
Giovanni Gigliotti
At present, taking into account the sustainability of the starting matrices, the biogas production industry is continuously growing, especially in consideration of ecological transition and circularity. The present study deals with the development of anaerobic bioreactors aimed at valorizing two specific wastes of the olive oil supply chain, i.e., the residual of protein hydrolysis process of three-phases olive pomace (OP-PH) and that recovered after the extraction of bioactive molecules from olive mill wastewater (OMWW waste). The energy consumed for biogas production varied from 0.52 kJ (OP and OMWW waste) to 0.97 kJ (OP-PH), while the energy produced for OP, OP-PH and OMMW waste was equal to 1.73, 2.94 and 1.60 kJ, respectively. The optimal production period was defined by considering only the range showing energy production higher than its consumption. According to this, OMWW showed the best performances, since it required 9 days (instead of 12 of untreated and treated OP) to reach the completion. The biogas production efficiency of the three-phase OP-PH waste calculated in the optimal production period, i.e., 12 days, was higher than the other samples, with a yield of 76.7% and a quantity of energy potentially producible corresponding to 1727.8 kJ/kg of volatile solids. These results pave the way for possible applications of this procedure for the planning of a multi-purpose biorefinery fed with by-products from the olive supply chain waste, thus promoting the use of sustainable waste materials from a circular economy perspective.

Verified
Journal Article
Open access
PDF file
EVElodie Vandelle
Elodie Vandelle
PAPietro Ariani
Pietro Ariani
ARAlice Regaiolo
Alice Regaiolo
DDDavide Danzi
Davide Danzi
ALArianna Lovato
Arianna Lovato
APAnnalisa Polverari
Annalisa Polverari
Downy mildew, caused by Plasmopara viticola, is one of the most severe diseases of grapevine (Vitis vinifera L.). Genetic resistance is an effective and sustainable control strategy, but major resistance genes (encoding receptors for specific pathogen effectors) introgressed from wild Vitis species, although effective, may be non-durable because the pathogen can evolve to avoid specific recognition. Previous transcriptomic studies in the resistant species Vitis riparia highlighted the activation of signal transduction components during infection. The transfer of such components to V. vinifera might confer less specific and therefore more durable resistance. Here, we describe the generation of transgenic V. vinifera lines constitutively expressing the V. riparia E3 ubiquitin ligase gene VriATL156. Phenotypic and molecular analysis revealed that the transgenic plants were less susceptible to P. viticola than vector-only controls, confirming the role of this E3 ubiquitin ligase in the innate immune response. Two independent transgenic lines were selected for detailed analysis of the resistance phenotype by RNA-Seq and microscopy, revealing the profound reprogramming of transcription to achieve resistance that operates from the earliest stages of pathogen infection. The introduction of VriATL156 into elite grapevine cultivars could therefore provide an effective and sustainable control measure against downy mildew.

18 October 2024 in Foods
Verified
Journal Article
Open access
PDF file
SPSilvia Portarena
Silvia Portarena
SPSimona Proietti
Simona Proietti
SMStefano Moscatello
Stefano Moscatello
CZClaudia Zadra
Claudia Zadra
NCNicola Cinosi
Nicola Cinosi
Daniela FarinelliDaniela Farinelli
Daniela Farinelli
Optimizing planting density is crucial for balancing resource competition, light penetration, and tree productivity in orchard systems. This study investigateed the impact of planting density on the yield and fruit quality of the hazelnut cultivar ‘Tonda Francescana®’ grafted onto Corylus colurna L. rootstocks. The research aimed to assess how different planting densities influenced light penetration, canopy volume, yield, and the nutritional profile of hazelnuts during their sixth growing season. Three planting densities were tested: 625, 1250, and 2500 trees per hectare (low, medium, and high density, respectively). The results show that medium-density planting provided the best balance between light availability, canopy development, and yield efficiency. The synthesis of monounsaturated fatty acids (MUFA) and α-tocopherol (vitamin E) was more prominent in the medium-density system (80.2% and 10.3%, respectively), suggesting a favorable metabolic response to moderate competition for resources. In contrast, high-density planting yielded the most per hectare (2898 kg/ha) but exhibited lower individual tree productivity (1.16 kg). Low-density planting had the highest light penetration (53%) but lower overall yield (822 kg/ha) and quality, with greater starch accumulation in the fruit. In general, medium-density planting optimized both yield and kernel quality, with potential implications for orchard management and breeding strategies to enhance hazelnut production and nutritional value.