Eduard Radu Cernei

Dr. Eduard Radu Cernei

Orthodontics, Grigore T. Popa University of Medicine and Pharmacy, Iaşi, Romania
orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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22 February 2023 in Applied Sciences
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RFRamona Diana Feier
Ramona Diana Feier
RCRadu Mircea Sireteanu Cucui
Radu Mircea Sireteanu Cucui
RRRamona Flavia Ratiu
Ramona Flavia Ratiu
DBDana Baciu
Dana Baciu
CGCarmen Galea
Carmen Galea
Eduard Radu CerneiEduard Radu Cernei
Eduard Radu Cernei
(1) Background: Currently, more and more studies reveal the fact that the use of ozonated oil in dentistry brings visible benefits. The aim of this study was to evaluate the efficacy of ozonated olive oil by evaluating daily index changes (2) Methods: The available products were used in this study: ozonized olive oil (Ozon Relive) and organic cold-pressed extra virgin olive oil. At the start of the study, all mouthwashes are placed in the same type of containers and labeled with numbers from 1 to 20. The recommended dose is one teaspoon of oil, about 6 mL per day. (3) Results: Ozonated oil (Group 1) and olive oil (Group 2) groups showed statistically significant differences to oral indices (p < 0.001 in both). (4) Conclusions: The results suggested that ozonized olive oil can be fully included among the products able to assist in controlling the causative factors of gingivitis while reducing its clinical manifestations.

12 January 2022 in Materials
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ARAna-Maria Roman
Ana-Maria Roman
VGVictor Geantă
Victor Geantă
Ramona CimpoesuRamona Cimpoesu
Ramona Cimpoesu
Corneliu MunteanuCorneliu Munteanu
Corneliu Munteanu
Lohan Nicoleta-MonicaLohan Nicoleta-Monica
Lohan Nicoleta-Monica
NINicoleta Ioanid
Nicoleta Ioanid
Special materials are required in many applications to fulfill specific medical or industrial necessities. Biodegradable metallic materials present many attractive properties, especially mechanical ones correlated with good biocompatibility with vivant bodies. A biodegradable iron-based material was realized through electric arc-melting and induction furnace homogenization. The new chemical composition obtained presented a special property named SME (shape memory effect) based on the martensite transformation. Preliminary results about this special biodegradable material with a new chemical composition were realized for the chemical composition and structural and thermal characterization. Corrosion resistance was evaluated in Ringer’s solution through immersion tests for 1, 3, and 7 days, the solution pH was measured in time for 3 days with values for each minute, and electro-corrosion was measured using a potentiostat and a three electrode cell. The mass loss of the samples during immersion and electro-corrosion was evaluated and the surface condition was studied by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). SME was highlighted with differential scanning calorimetry (DSC). The results confirm the possibility of a memory effect of the materials in the wrought case and a generalized corrosion (Tafel and cyclic potentiometry and EIS) with the formation of iron oxides and a corrosion rate favorable for applications that require a longer implantation period.

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GCgrierosu carmen
grierosu carmen
GABRIELA CALIN (MIHALACHE)GABRIELA CALIN (MIHALACHE)
GABRIELA CALIN (MIHALACHE)
DDDaniela Damir
Daniela Damir
CMConstantin Marcu
Constantin Marcu
Eduard Radu CerneiEduard Radu Cernei
Eduard Radu Cernei
LELucian Eva
Lucian Eva
Nowadays, infection diseases are one of the most significant threats to humans all around the world. An encouraging strategy for solving this issue and fighting resistant microorganisms is to develop drug carriers for a prolonged release of the antibiotic to the target site. The purpose of this work was to obtain metronidazole-encapsulated chitosan nanoparticles using an ion gelation route and to evaluate their properties. Due to the advantages of the ionic gelation method, the synthesized polymeric nanoparticles can be applied in various fields, especially pharmaceutical and medical. Loading capacity and encapsulation efficiency varFied depending on the amount of antibiotic in each formulation. Physicochemical characterization using scanning electron microscopy revealed a narrow particle size distribution where 90% of chitosan particles were 163.7 nm in size and chitosan-loaded metronidazole nanoparticles were 201.3 nm in size, with a zeta potential value of 36.5 mV. IR spectra revealed characteristic peaks of the drug and polymer nanoparticles. Cell viability assessment revealed that samples have no significant impact on tested cells. Release analysis showed that metronidazole was released from the chitosan matrix for 24 h in a prolonged course, implying that antibiotic-encapsulated polymer nanostructures are a promising drug delivery system to prevent or to treat various diseases. It is desirable to obtain new formulations based on drugs encapsulated in nanoparticles through different preparation methods, with reduced cytotoxic potential, in order to improve the therapeutic effect through sustained and prolonged release mechanisms of the drug correlated with the reduction of adverse effects.

10 August 2024 in Medicina
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BNBotezatu Stan Alexandra Nina
Botezatu Stan Alexandra Nina
Eduard Radu CerneiEduard Radu Cernei
Eduard Radu Cernei
GZGeorgeta Zegan
Georgeta Zegan
Background and Objectives: Facial symmetry is a key component of facial beauty and attractiveness. However, perfect symmetry is rare, and slight asymmetries, also known as natural asymmetries, are common and contribute to the uniqueness of each face. The perception of facial asymmetry varies among individuals and can be influenced by several factors. This study aimed to investigate the self-perception of dento-facial asymmetry among a sample of Romanian individuals, focusing on their awareness, the extent to which it bothers them, and their desire for correction. Materials and Methods: A cross-sectional analytical study was conducted with 283 participants from Romania between January and February 2024. Participants completed a questionnaire designed to assess their self-perception of facial asymmetry and socio-demographic characteristics. The questionnaire included 10 questions on self-perception of facial asymmetry and 8 questions on socio-demographic data. Statistical analysis was performed using SPSS 26.0, and the Pearson Chi-square test was used for comparative analysis. Results: The sample was predominantly female (75.3%) with an average age of 32.24 years. Most participants were from urban areas (80.6%) and had university degrees (58.7%). About 28.7% of participants observed facial asymmetry, with dental asymmetry being the most frequently reported, followed by asymmetries in the eyebrows and eyelids. The right side of the face was more commonly perceived as asymmetric. Although 24.4% of participants were bothered by their asymmetry, 39.2% expressed a desire to correct it. Conclusions: One-third of participants identified dento-facial asymmetry, with the dental level being the most reported. A significant portion of participants expressed a desire to correct their asymmetries, highlighting the importance of understanding self-perception in the context of facial aesthetics. This study underscores the subjective nature of facial asymmetry perception and the varying thresholds for what is considered bothersome or in need of correction.

19 June 2025 in Medicina
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NONicolae Daniel Olteanu
Nicolae Daniel Olteanu
CRCristian Romanec
Cristian Romanec
Eduard Radu CerneiEduard Radu Cernei
Eduard Radu Cernei
NKNikolaos Karvelas
Nikolaos Karvelas
LNlivia nastri
livia nastri
Irina nicoleta ZetuIrina nicoleta Zetu
Irina nicoleta Zetu
Background and Objectives: Anterior open-bite malocclusion remains a challenging orthodontic condition where achieving a positive overbite necessitates precise control of incisor extrusion and molar intrusion. With recent advances in clear aligner therapy—improved materials, attachment techniques and digital treatment planning—the potential for non-invasive treatment has increased. This scoping review systematically maps the evidence on the efficacy of clear aligners in treating anterior open bite among adult patients, outlines treatment protocols and highlights gaps in the literature. Materials and Methods: A systematic search was conducted in PubMed/Medline, Embase/ScienceDirect and Clarivate/Web of Science for literature published in English between January 2000 and December 2024. Studies involving adult patients treated with clear aligners (predominantly Invisalign®) were included. A two-step screening process was applied, and data were charted according to pre-specified criteria. The review adheres to the PRISMA-ScR checklist guidelines. Results: From an initial pool of 802 articles, 30 met the inclusion criteria following duplicate removal and full-text screening. The evidence suggests that clear aligners can achieve measurable incisor extrusion and posterior intrusion when appropriate auxiliary techniques (e.g., attachments and mini screws) are used. However, digital treatment planning software may overestimate movement predictions, necessitating iterative refinement phases. Patient compliance, clinician expertise and technological limitations are key factors influencing outcomes. Conclusions: Clear aligner therapy represents a promising alternative to fixed appliances for anterior open-bite correction in adults, although challenges remain in achieving precise vertical control. Further high-quality randomized controlled trials and standardized outcome measures are needed to confirm long-term stability and efficacy.

22 May 2023 in Applied Sciences
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Eduard Radu CerneiEduard Radu Cernei
Eduard Radu Cernei
ACAlice Chehab
Alice Chehab
NONicolae Daniel Olteanu
Nicolae Daniel Olteanu
CRCristian Romanec
Cristian Romanec
Tinela PanaiteTinela Panaite
Tinela Panaite
Irina nicoleta ZetuIrina nicoleta Zetu
Irina nicoleta Zetu
Passive self-ligating bracket systems (PSLBs), such as the Damon® system (Ormco, US) and SmartClip (3M Unitek®, US) claim advantages over other types of brackets regarding efficiency and effectiveness. However, some studies have questioned their qualities, particularly during the alignment stage, in arch development, and regarding stability of results. This article aims to conduct a scoping review from the past decade’s literature (2013–2023) regarding these assertions about PSLBs. A comprehensive search was performed on several databases. With at least one comparison between PSLBs and the other two bracket types, the inclusion criteria were restricted to English-written randomized controlled trials and split-mouth design studies involving patients receiving orthodontic treatment using PSLB, active self-ligating bracket systems (ASLBs), or conventional/traditional bracket systems (CBs). After screening and manual analysis of the selected studies, only 39 were chosen for the review. Most of the efficiency and effectiveness results from research conducted in the past ten years did not indicate any appreciable differences between the three different types of brackets; therefore, the evidence on whether PSLB is better than CBs and ASLBs is equivocal. Further research is necessary to understand the distinctions between passive self-ligating and other bracket systems and establish the optimal utilization of each system in clinical settings.