Pierangela Rovellini

Dr. Pierangela Rovellini

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Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 January 2023 in Foods
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SPStefania Pagliari
Stefania Pagliari
MFMatilde Forcella
Matilde Forcella
ELElena Lonati
Elena Lonati
GSGrazia Sacco
Grazia Sacco
FRFrancesco Romaniello
Francesco Romaniello
IBIlaria Bruni
Ilaria Bruni
Cinnamon bark is widely used for its organoleptic features in the food context and growing evidence supports its beneficial effect on human health. The market offers an increasingly wide range of food products and supplements enriched with cinnamon extracts which are eliciting beneficial and health-promoting properties. Specifically, the extract of Cinnamomum spp. is rich in antioxidant, anti-inflammatory and anticancer biomolecules. These include widely reported cinnamic acid and some phenolic compounds, such asproanthocyanidins A and B, and kaempferol. These molecules are sensitive to physical-chemical properties (such as pH and temperature) and biological agents that act during gastric digestion, which could impair molecules’ bioactivity. Therefore, in this study, the cinnamon’s antioxidant and anti-inflammatory bioactivity after simulated digestion was evaluated by analyzing the chemical profile of the pure extract and digested one, as well as the cellular effect in vitro models, such as Caco2 and intestinal barrier. The results showed that the digestive process reduces the total content of polyphenols, especially tannins, while preserving other bioactive compounds such as cinnamic acid. At the functional level, the digested extract maintains an antioxidant and anti-inflammatory effect at the cellular level.

5 March 2020 in Foods
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LCLanfranco Conte
Lanfranco Conte
AMAndrea Milani
Andrea Milani
SCSonia Calligaris
Sonia Calligaris
PRPierangela Rovellini
Pierangela Rovellini
PLPaolo Lucci
Paolo Lucci
MNMaria Cristina Nicoli
Maria Cristina Nicoli
Producers have to guarantee the extra virgin olive oil (EVOO) quality characteristics reported in the Regulation (CEE) 2568/91 throughout the product shelf-life (SL). Unfortunately, due to the development of oxidative reactions, some quality indices change during storage leading to a progressive deterioration of EVOO quality. To avoid the risk of product downgrading in the virgin oil category, the development of effective shelf-life prediction models is extremely important for the olive oil industry. In this research, the accelerated shelf-life testing (ASLT) protocol was applied to evaluate the temperature dependence of selected oxidation indexes as well as to develop a shelf-life predictive model. The evolution of conventional (peroxide value, K232, K270, polyphenols, tocopherols and hexanal) and unconventional parameters (conjugated trienes and pyropheophytin a) was monitored in bottled EVOO stored in the dark at increasing temperature (25, 40, 50 and 60 °C). Accordingly, for well-packed products with reduced oxygen in headspace, the best shelf-life index allowing the ability to predict EVOO SL turned out to be K270. In addition, pyropheophytin a (%) has been shown to be more sensitive to temperature changes than the secondary oxidation indices, thus suggesting its use as a freshness indicator for storage temperatures higher than 25 °C.


11 December 2020 in OCL
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PBPaolo Bondioli
Paolo Bondioli
LFLiliana Folegatti
Liliana Folegatti
PRPierangela Rovellini
Pierangela Rovellini
In this paper, the main chemical properties of Perilla seed oil (PO) obtained by mechanical pressing of Perilla seeds are reported. The analysis of fatty acid composition has highlighted a very high amount of (n-3) α-linolenic acid (ALA), more than 60%, higher than other ALA rich oils such as linseed and sacha inchi oils and similar to chia oil. PO has an important sterol (higher than 3000 mg/kg) and vitamin E (approx. 870 mg/kg) content, while biophenols are in quite low concentration. The analyzed sample showed a very low acid and peroxide value and this is the demonstration that, following the proper technological procedures, it is possible to obtain high quality oils even in presence of high α-linolenic acid concentrations.

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ELElena Lonati
Elena Lonati
GSGessica Sala
Gessica Sala
PCPaolo Corbetta
Paolo Corbetta
SPStefania Pagliari
Stefania Pagliari
ECEmanuela Cazzaniga
Emanuela Cazzaniga
ABAlessandra Bulbarelli
Alessandra Bulbarelli
Epigenetic changes, host–gut microbiota interactions, and environmental factors contribute to inflammatory bowel disease (IBD) onset and progression. A healthy lifestyle may help to slow down the chronic or remitting/relapsing intestinal tract inflammation characteristic of IBD. In this scenario, the employment of a nutritional strategy to prevent the onset or supplement disease therapies included functional food consumption. Its formulation consists of the addition of a phytoextract enriched in bioactive molecules. A good candidate as an ingredient is the Cinnamon verum aqueous extract. Indeed, this extract, subjected to a process of gastrointestinal digestion simulation (INFOGEST), exhibits beneficial antioxidant and anti-inflammatory properties in an in vitro model of the inflamed intestinal barrier. Here, we deepen the study of the mechanisms related to the effect of digested cinnamon extract pre-treatment, showing a correlation between transepithelial electrical resistance (TEER) decrement and alterations in claudin-2 expression under Tumor necrosis factor-α/Interleukin-1β (TNF-α/IL-1) β cytokine administration. Our results show that pre-treatment with cinnamon extract prevents TEER loss by claudin-2 protein level regulation, influencing both gene transcription and autophagy-mediated degradation. Hence, cinnamon polyphenols and their metabolites probably work as mediators in gene regulation and receptor/pathway activation, leading to an adaptive response against renewed insults.

3 June 2020 in Comunicata Scientiae
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MDMounsif Charaf-Eddine Bendi Djelloul
Mounsif Charaf-Eddine Bendi Djelloul
SASidi Mohamed Amrani
Sidi Mohamed Amrani
PRPierangela Rovellini
Pierangela Rovellini
RCRoza Chenoune
Roza Chenoune
Olive represents the most widespread fruit cultivated in Algeria. Olive oil is the primary source of added fat in the Mediterranean diet with health benefits of which have been verified for millennia. Interest in phenolic compounds in olive oil has increased due to its antioxidant activity, which plays a very important role in human health. The present study is carried out to study the phenolic compounds and fatty acids profile of some olive oils from western Algeria. The quality parameters (acidity, peroxide value, K232, K270), tocopherol analysis, fatty acid composition and phenolic profile were determined by High performance chromatography (HPLC). The results showed that chemlal oil (SBA) recorded the highest level of tocopherol-α with 228.12 mg/Kg. Regarding the fatty acid composition, oleic acid was the most dominant, oil Oleaster (Bensekrane) records the highest percentage (72.80%) of oleic acid. The quantitative data on the phenolic content of the seven samples revealed that chemlal oil (SBA) had the highest level of polyphenols (328.99 mg/Kg). However, Sigoise oil (Sebra1) was characterized by the highest levels of tyrosol and hydroxytyrosol (15.89 mg/kg and 22.42 mg/kg, respectively). The highest concentrations of oleuropein derivatives and ligstroside derivatives were observed in chemlal oil (SBA) and the recoreded values were 105.97 mg/Kg and 83.49 mg/Kg, respectively. Chemlal oil (SBA) was characterized by the highest amount of lignans (35.93 mg/Kg), luteolin (10.16 mg/Kg) and apigenin (5.44 mg/Kg). Oleocanthal was found in all the tested samples and it was higher in Chemlal oil (102.43 mg/kg).